New high resolution radiation dose mapping of special type polymer-gel dosimeters using mini-MRI scanner of high (4.7 Tesla) magnetic field. Gel dosimeters main advantage is dose determination in 3-dimensions. Their main limitation is low spatial-resolution. We propose fabrication of special-type gels and for the first time use the 4.7 Tesla mini-scanner for dose mapping. Increased magnetic field combined with a small aperture for field dissipation will greatly improve spatial resolution down t ....New high resolution radiation dose mapping of special type polymer-gel dosimeters using mini-MRI scanner of high (4.7 Tesla) magnetic field. Gel dosimeters main advantage is dose determination in 3-dimensions. Their main limitation is low spatial-resolution. We propose fabrication of special-type gels and for the first time use the 4.7 Tesla mini-scanner for dose mapping. Increased magnetic field combined with a small aperture for field dissipation will greatly improve spatial resolution down to micrometers (micro-dosimetry). This new technique will render gel-dosimeters suitable for applications in radiotherapy, industrial and all other radiation fields. Moreover, we will employ new parameter for dose mapping, which is expected to be more sensitive to radiation than the currently used relaxation timesRead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454184
Funder
Australian Research Council
Funding Amount
$155,792.00
Summary
Silicon Imaging Device Construction Facility - Wirebonder. The development of state-of-the-art, high precision semiconductor imaging devices (for high energy particle physics, synchrotron science and medical imaging ) requires a significant capability in modern assembly facilities. In constructing test and 'production' modules consisting of fine-grained, multi-channel bare silicon or other semiconductor imaging devices and custom electronic chips, a high-reliability, highly flexible wire-bonding ....Silicon Imaging Device Construction Facility - Wirebonder. The development of state-of-the-art, high precision semiconductor imaging devices (for high energy particle physics, synchrotron science and medical imaging ) requires a significant capability in modern assembly facilities. In constructing test and 'production' modules consisting of fine-grained, multi-channel bare silicon or other semiconductor imaging devices and custom electronic chips, a high-reliability, highly flexible wire-bonding machine is an essential tool. The international reputation from success in several challenging projects under difficult conditions, gained by the Chief Investigators has resulted in several more projects being planned in addition to a foreseen program of device development. A modern wirebonder, to replace the existing 30 year-old machine, has become critical to maintain our leading position in this area.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560716
Funder
Australian Research Council
Funding Amount
$864,610.00
Summary
A National T-ray Facility. T-rays are between microwaves and infrared on the electromagnetic spectrum. Recently, advances in femtosecond lasers enabled access to T-ray frequencies, producing an important new imaging modality for non-invasive sensing of materials and structures. Internationally, T-rays represent a rich new science leading to advanced forms of biophotonics, biomedical imaging and spectroscopy. Non-invasive T-ray diagnostics of nano- and bio-materials are being hotly pursued. The o ....A National T-ray Facility. T-rays are between microwaves and infrared on the electromagnetic spectrum. Recently, advances in femtosecond lasers enabled access to T-ray frequencies, producing an important new imaging modality for non-invasive sensing of materials and structures. Internationally, T-rays represent a rich new science leading to advanced forms of biophotonics, biomedical imaging and spectroscopy. Non-invasive T-ray diagnostics of nano- and bio-materials are being hotly pursued. The outcome will be a strategically important Australian T-ray facility that will provide immediate and transparent nationwide access. Historically, industry is transformed every time a new part of the electromagnetic spectrum becomes accessible - T-rays are the next frontier.Read moreRead less
Comparison of Techniques for the Removal of Ocular Artefact from the Electroencephalogram: A Validation Study. Although employed extensively for both research and clinical purposes, the utility of the electroencephalograph (EEG) is hampered by the contaminating effects of eye movements on these 'brain waves'. If it can be validated, the recent Australian development of a solution to this problem will mean that the EEG can be measured more quickly and accurately. This purpose of this research is ....Comparison of Techniques for the Removal of Ocular Artefact from the Electroencephalogram: A Validation Study. Although employed extensively for both research and clinical purposes, the utility of the electroencephalograph (EEG) is hampered by the contaminating effects of eye movements on these 'brain waves'. If it can be validated, the recent Australian development of a solution to this problem will mean that the EEG can be measured more quickly and accurately. This purpose of this research is to perform this validation, and its success would mean both more efficient EEG recording for the country, as well as an enhanced scientific reputation.Read moreRead less
DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to und ....DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to understand and quantify factors influencing droplet deformation. Coupling non-Newtonian characteristics with microfluidic geometries will allow the continuous manufacture of micro-particles of specified size and shape for existing and new applications, and will provide guidance for further extending the process to nano-particle manufacture.Read moreRead less
Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface cha ....Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface charge, and the numerical predictions. This understanding will complement development in related projects on non-Newtonian drop and particle formation in microfluidic flows which envisage continuous particle manufacture for novel materials possessing programmable, enhanced functional properties.Read moreRead less
Advanced technologies for laser refractive surgery. People who wear glasses can now undergo laser eye-surgery to correct their focussing problems. While many can ?throw away their glasses?, the results are optimised for one viewing situation so that when people move their eyes or refocus, visual clarity is not perfect. We need precise measurements of the eye's shape under dynamic conditions to understand exactly how optical distortions (aberrations) affect clarity of sight. This project is to b ....Advanced technologies for laser refractive surgery. People who wear glasses can now undergo laser eye-surgery to correct their focussing problems. While many can ?throw away their glasses?, the results are optimised for one viewing situation so that when people move their eyes or refocus, visual clarity is not perfect. We need precise measurements of the eye's shape under dynamic conditions to understand exactly how optical distortions (aberrations) affect clarity of sight. This project is to build a laser device that incorporates a deformable mirror to investigate the interplay between aberrations and visual clarity. This new knowledge is a vital next step to improve laser eye-surgery success.Read moreRead less
New quantitative methods in X-ray imaging using crystal optics. This project will enhance Australian science's international leadership in the area of x-ray imaging. This powerful type of X-ray imaging, which makes use of optical elements made of perfect crystals, is specially tailored to image samples which are invisible to conventional x-ray techniques. Such "extended x-ray vision" is extremely important for imaging in medicine, biology and materials science. Furthermore, we will train x-ray s ....New quantitative methods in X-ray imaging using crystal optics. This project will enhance Australian science's international leadership in the area of x-ray imaging. This powerful type of X-ray imaging, which makes use of optical elements made of perfect crystals, is specially tailored to image samples which are invisible to conventional x-ray techniques. Such "extended x-ray vision" is extremely important for imaging in medicine, biology and materials science. Furthermore, we will train x-ray scientists of tomorrow, whose expertise will allow Australia to capitalize on its investment in the Australian Synchrotron.Read moreRead less
Understanding surface acoustic wave atomisation for pulmonary delivery of drug aerosols in personalised medicine. Delivering drugs via the lung is hampered by development costs and inadequate technology. This project will provide an understanding of atomisation in our unique respire system, enabling not only the delivery of new vaccines and drugs but also the rapid and cost effective development of new disease treatments personalised to the patient.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347024
Funder
Australian Research Council
Funding Amount
$140,000.00
Summary
Research facility in micromanipulation. The aim of the program is to establish a unique joint facility between Monash and Deakin for micromanipulation research. The proposed facility will consist of complex/intelligent micromanipulation systems capable of motion accuracy of 0.01-0.1 micrometer (10-100 nm). This will be the only facility of its kind in Australia and will provide a key enabling technology in the research and development of advanced micromanipulation systems, robotic-assisted mic ....Research facility in micromanipulation. The aim of the program is to establish a unique joint facility between Monash and Deakin for micromanipulation research. The proposed facility will consist of complex/intelligent micromanipulation systems capable of motion accuracy of 0.01-0.1 micrometer (10-100 nm). This will be the only facility of its kind in Australia and will provide a key enabling technology in the research and development of advanced micromanipulation systems, robotic-assisted microsurgery, sensory-based and intelligent control of complex systems, micro assembly/manufacturing, telerobotics/telesurgery, kinematics and dynamics of micromanipulators, laser-based control, and biotechnology. The facility will support and enhance a number of high-quality, current and future research projects with recognised potential.Read moreRead less