The development and testing of a device to enhance the application of repetitive transcranial magnetic stimulation. This project aims to develop and evaluate a new device designed to substantially enhance the use of transcranial magnetic stimulation, a technology, which is increasingly being applied in the treatment of disorders such as depression, as well as in the study of normal and abnormal brain function.
Genetic dissection of functional-structural connectivity using optogenetic fMRI and dMRI tractography. The project will map the connectivity pattern of genetically defined neurons in mouse brain by combining state of the art molecular and neuroscience imaging technology. The outcome will be a significant step toward building a complete functional and structural mapping resource, with application for examining dysfunction in neurological disease models.
Investigating the molecular mechanisms underlying non-visual photoreception and their implications in the treatment of human neurological disease. The ability of organisms to detect light is fundamental for survival and has been a major driver in evolution. The project will investigate the genetic origins of the various visual and non-visual systems and will explore its implications for the bioengineering of therapeutics for the treatment of neurological disease in humans.
Special Research Initiatives - Grant ID: SR0354726
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
NETVISION: AUSTRALIA'S NATIONAL VISION RESEARCH NETWORK. Vision is the most important human sense. Visual malfunctions pose major health challenges. Vision provides a window into the brain, for studying perception, cognition and consciousness. It is integral to human cultural and social development. It provides opportunities for technological advances in diagnostics, artificial vision, robotics, and surveillance. Vision is therefore crucial to three of the National Priority Areas. The National V ....NETVISION: AUSTRALIA'S NATIONAL VISION RESEARCH NETWORK. Vision is the most important human sense. Visual malfunctions pose major health challenges. Vision provides a window into the brain, for studying perception, cognition and consciousness. It is integral to human cultural and social development. It provides opportunities for technological advances in diagnostics, artificial vision, robotics, and surveillance. Vision is therefore crucial to three of the National Priority Areas. The National Vision Network will create a coherent, interactive and innovative research base in the vision sciences, linked to end-users in areas ranging from the art, entertainment and fashion industries, through health and education, to border protection and counter-terrorism.Read moreRead less
Effect of infant hand observation training on the early development of hand reaching and grasping in healthy infants and those with early brain damage. The best way to learn a new motor skill is to look at people who can already do it. But is this also true for infants? And, can we help infants with motor problems by teaching them how to do it? This project aims to answer these questions by studying training based on the observation of parent's actions by infants with and without brain damage.
Discovery Early Career Researcher Award - Grant ID: DE130101222
Funder
Australian Research Council
Funding Amount
$371,392.00
Summary
The development of novel magnetic resonance imaging methods to investigate brain structure and function. Magnetic resonance imaging (MRI) is a non-invasive method that has revolutionised neuroscience. The goal of this project is to develop state-of-the-art MRI analysis methods that reveal new information about brain structure and function. These novel neuroimaging tools will be instrumental in furthering our understanding of how the brain works.
Advanced magnetic resonance imaging methods for the characterisation of brain structure and function. Magnetic resonance imaging (MRI) is a non-invasive method that has revolutionised the development of neuroscience and neurology. The goal of this project is to develop advanced MRI methods for the study of brain structure and function which will be applied to the investigation of epilepsy and stroke.
The processing of sensory information within cortical circuits. This project aims to improve our knowledge of neuronal activity during sensory perception and therefore shed light on overall brain function during behaviour. Understanding how dendrites receive and process this information is crucial to understanding brain function during sensory processing and perception. This proposal aims to characterise dendritic activity during sensory input and discover how this activity contributes to behavi ....The processing of sensory information within cortical circuits. This project aims to improve our knowledge of neuronal activity during sensory perception and therefore shed light on overall brain function during behaviour. Understanding how dendrites receive and process this information is crucial to understanding brain function during sensory processing and perception. This proposal aims to characterise dendritic activity during sensory input and discover how this activity contributes to behavioural tasks. In particular, the project plans to investigate activity of different dendritic domains during sensory perception and sensory-based behaviour. The project seeks to improve our knowledge of the importance of dendrites in transforming information from the sensory environment and highlight the cellular and network mechanisms contributing to behaviour.Read moreRead less
Comparison of Techniques for the Removal of Ocular Artefact from the Electroencephalogram: A Validation Study. Although employed extensively for both research and clinical purposes, the utility of the electroencephalograph (EEG) is hampered by the contaminating effects of eye movements on these 'brain waves'. If it can be validated, the recent Australian development of a solution to this problem will mean that the EEG can be measured more quickly and accurately. This purpose of this research is ....Comparison of Techniques for the Removal of Ocular Artefact from the Electroencephalogram: A Validation Study. Although employed extensively for both research and clinical purposes, the utility of the electroencephalograph (EEG) is hampered by the contaminating effects of eye movements on these 'brain waves'. If it can be validated, the recent Australian development of a solution to this problem will mean that the EEG can be measured more quickly and accurately. This purpose of this research is to perform this validation, and its success would mean both more efficient EEG recording for the country, as well as an enhanced scientific reputation.Read moreRead less
Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project ....Central Representation of Electroacoustic Stimuli. Cochlear implantation, initially only provided to profoundly deaf individuals, is now routine in people with substantial residual hearing. Although stimulation via a cochlear implant and hearing aid in the same ear has been shown to improve speech understanding, particularly in noise, and to increase the aesthetic quality of sound, almost nothing is known about the physiological mechanisms underlying these benefits. The broad aim of our project is to address this deficiency by measuring the patterns of neural activity evoked by speech sounds across the tonotopic axis in the inferior colliculus and auditory cortex and assess the extent to which the pattern of neural activity allows discrimination between the different speech sounds.Read moreRead less