The improvement of climate change investigations by developing and applying innovative evolutionary subset time series modelling using semi-parametric sparse-patterned approaches. With an estimated US$6.98 trillion loss indicated in the Stern review, severe climate change will make world climate conditions harsher and more likely include large natural climate disasters. The health of the Australian economy is critically dependent on decisions of environmental managers. However, most problems of ....The improvement of climate change investigations by developing and applying innovative evolutionary subset time series modelling using semi-parametric sparse-patterned approaches. With an estimated US$6.98 trillion loss indicated in the Stern review, severe climate change will make world climate conditions harsher and more likely include large natural climate disasters. The health of the Australian economy is critically dependent on decisions of environmental managers. However, most problems of complexity arising in climate change involve issues on which we do not possess a deep understanding. This project draws upon a set of inter-disciplinary concepts and models centred in neural networks that enable us to advance our understanding of complexity, leading to superior quantitative tools and models to allow for improved environmental decision-making.
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Refinement of dynamic combinatorial chemistry as a drug discovery tool. Medicinal chemistry is constantly being challenged to develop efficient methodologies for the synthesis of compounds for drug discovery. Following completion of the Human Genome project, the cloning and expression of new proteins will proceed at an accelerated rate. In the absence of biochemical knowledge of the target protein there is a growing interest in techniques that expand the structural and biological diversity of co ....Refinement of dynamic combinatorial chemistry as a drug discovery tool. Medicinal chemistry is constantly being challenged to develop efficient methodologies for the synthesis of compounds for drug discovery. Following completion of the Human Genome project, the cloning and expression of new proteins will proceed at an accelerated rate. In the absence of biochemical knowledge of the target protein there is a growing interest in techniques that expand the structural and biological diversity of compound libraries. Dynamic combinatorial chemistry is an innovative technology with the capacity for supporting the shift from focussed to diverse compound libraries. This application seeks funding to refine dynamic combinatorial chemistry into an effective drug discovery tool.Read moreRead less
Computer Modelling of the Morphology and Crystallography of Diffusion-controlled Phase Transformations. An analytical, phenomenological version of the successful "edge-to edge" matching approach to the morphology and crystallography of diffusion-controlled phase transformations will be developed. This will be incorporated in a Windows based computer program that can predict the essential features of precipitation (orientation relationships, habit planes, morphology and interface structure), fro ....Computer Modelling of the Morphology and Crystallography of Diffusion-controlled Phase Transformations. An analytical, phenomenological version of the successful "edge-to edge" matching approach to the morphology and crystallography of diffusion-controlled phase transformations will be developed. This will be incorporated in a Windows based computer program that can predict the essential features of precipitation (orientation relationships, habit planes, morphology and interface structure), from readily available input data for the two phases involved. It will provide a fuller understanding of diffusion-controlled phase transformations and the computer simulation will assist in the development of improved precipitation hardening alloys. In addition, a database of crystallographic data for typical metallic materials will be established in the project.Read moreRead less
Formally-Based Security Evaluation Procedures. Guaranteeing information security is of critical national importance, especially in the current political climate. Devices intended to safeguard Australia's electronic communications must be proven secure using leading-edge techniques. Currently, evaluation of such devices relies on informal procedures and the experience of individuals. This project will introduce more rigour into security evaluations by adapting techniques from the fields of saf ....Formally-Based Security Evaluation Procedures. Guaranteeing information security is of critical national importance, especially in the current political climate. Devices intended to safeguard Australia's electronic communications must be proven secure using leading-edge techniques. Currently, evaluation of such devices relies on informal procedures and the experience of individuals. This project will introduce more rigour into security evaluations by adapting techniques from the fields of safety analysis and formal methods. In particular, mathematical concepts will be introduced using notations suitable for use by security personnel with no prior formal methods experience. The outcomes of this project will enable more efficient and effective information security evaluations.Read moreRead less
A Formal Approach to Resource Allocation in Service Oriented Marketplaces. There was a strong opinion at the 2004 World Economic Forum that interorganisational computing was a major factor in productivity improvements underpinning continuing economic growth in the developed world, and will continue to be so for the foreseeable future. The results of the proposed research are directed to advanced systems of this type, and will add momentum to Australia's Information Technology research community. ....A Formal Approach to Resource Allocation in Service Oriented Marketplaces. There was a strong opinion at the 2004 World Economic Forum that interorganisational computing was a major factor in productivity improvements underpinning continuing economic growth in the developed world, and will continue to be so for the foreseeable future. The results of the proposed research are directed to advanced systems of this type, and will add momentum to Australia's Information Technology research community. Increased international recognition will positively impact on future interactions with the service composition research groups in Europe and the USA.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775649
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
An Integrated Multi-Node Microfluidics Facility. The establishment of the proposed facility will enhance Australia's position in microfluidics research, thus contributing to all National Priority areas, particularly the National Priority area 3 through advancement in breakthrough science and frontier technologies. In addition to researchers from participating institutions, the Facility will be made available to other Australian researchers from non-participating organisations at minimum cost. Th ....An Integrated Multi-Node Microfluidics Facility. The establishment of the proposed facility will enhance Australia's position in microfluidics research, thus contributing to all National Priority areas, particularly the National Priority area 3 through advancement in breakthrough science and frontier technologies. In addition to researchers from participating institutions, the Facility will be made available to other Australian researchers from non-participating organisations at minimum cost. The socio-economic potentials of the research carried out using the proposed facility are significant and include: R&D development, small scale high technology manufacture, exports, and improved methods of biochemical processing and medical diagnostics.Read moreRead less
Special Research Initiatives - Grant ID: SR0354797
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance co ....The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance communication, bring together innovative skill sets, create linkages, generate focussed research programs and foster novel commercial opportunities. Ultimately the Initiative and Network will deliver an improved quality of life, reduced healthcare costs, and increased productivity to Australia.Read moreRead less
Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully unde ....Coordination and communication in critical care: Assessing potential technology support. This project will examine temporal coordination demands of busy critical care environments, with the goal of developing better models and tools for evaluating the impact of information and communication technology (ICT) innovation. Millions of dollars can be wasted on healthcare ICT updates when the nature of critical care work, the means of communication, and temporal coordination demands are not fully understood. The outcome of this project will be better conceptual and computational tools for assessing the impact of ICT innovation on safety-critical systems such as healthcare, so providing more cost-effective ICT solutions where there is rapidly-evolving ICT innovation.Read moreRead less
ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand add ....ARC Centre for Complex Systems. The Australian Centre for Complex Systems brings together leading researchers from several disciplines and institutions to conduct research on questions fundamental to understanding and managing complex systems. Its core research program, based on the theme of computation in and by networks of agents, has two interwoven strands. The science strand addresses questions about emergent properties, natural computation, and nonlinear dynamics. The engineering strand addresses issues about methodology, modelling toolkits, and management and control. Practical applications are advanced via collaborative projects that address key issues in biology, environment, and socio-economics.Read moreRead less
Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographic ....Atmospheric fate and processes of semi-volatile organic compounds in tropical climates. The outcomes from this study will contribute fundamental and quantitative information for evaluation of the fate of semi-volatile organic compounds (SOCs) in tropical systems, including Australia's World Heritage ecosystems such as rainforest and the Great Barrier Reef. The study addresses key international knowledge gaps with respect to the influence of climate on SOC atmospheric fate. Australia's geographical location within the tropical belt provides an ideal opportunity for leading this field of research and contributes relevant data for its commitment under the Stockholm Convention.Read moreRead less