A single vaccine for influenza and pneumonia. Influenza and bacterial pneumonia collaborate to kill millions of people each year. This project aims to develop a single vaccine that will provide long-lasting protection against both influenza and pneumonia.
Improved methods for quantitation of acute phase proteins in biological samples. Using monoclonal antibodies and fluorescence polarisation, we aim to develop improved quantitative analytical methods that are superior to the current clinical assays. The initial targets will be C-reactive protein (CRP) and serum amyloid precursor protein (SAP), but the technology should be readily adaptable to other serum proteins. Better assays for CRP and SAP will greatly facilitate improved clinical management ....Improved methods for quantitation of acute phase proteins in biological samples. Using monoclonal antibodies and fluorescence polarisation, we aim to develop improved quantitative analytical methods that are superior to the current clinical assays. The initial targets will be C-reactive protein (CRP) and serum amyloid precursor protein (SAP), but the technology should be readily adaptable to other serum proteins. Better assays for CRP and SAP will greatly facilitate improved clinical management of those at risk of heart attack, the single biggest contributor to healthcare costs in Australia. We further aim to adapt this technology to enable "point-of-care" assays that would help medical practitioners, especially in rural areas, to make informed diagnoses immediately.Read moreRead less
Imaging Mass Spectrometry (IMS), a peptide biomarker discovery tool using tissue. Cancer is the second most common cause of death in Australia. The newly developed technology of Imaging Mass Spectrometry for peptides in tissue has the potential to discover biomarkers for early diagnosis of cancer. This new technology could avoid a number of cancer deaths and reduce suffering of patients through earlier and better diagnosis.
Long Chain Omega-3 Polyunsaturated Fatty Acids and Heart Health in Humans. The primary aims of the project is to assess the effect of DHA rich tuna oil on cholesterol carrying lipoproteins and to determine a quicker method in assessing someone's omega-3 status. The expected outcomes include the determination of: 1) the most appropriate blood sample and a rapid test and for evaluating the omega-3 status; 2) the minimum dose of tuna oil required which will not only improve a person's omega-3 statu ....Long Chain Omega-3 Polyunsaturated Fatty Acids and Heart Health in Humans. The primary aims of the project is to assess the effect of DHA rich tuna oil on cholesterol carrying lipoproteins and to determine a quicker method in assessing someone's omega-3 status. The expected outcomes include the determination of: 1) the most appropriate blood sample and a rapid test and for evaluating the omega-3 status; 2) the minimum dose of tuna oil required which will not only improve a person's omega-3 status but also improve their plasma lipid profile and hence reduce their overall risk for cardiovascular disease (CVD); and 3) the use of the Omega-3 Index by medical practitioners. The significance is the increased knowledge of the health benefits of DHA rich tuna oil and that a new CVD risk marker will be generally accepted.Read moreRead less
Australia’s first direct-detection dark matter search, at Stawell Gold Mine. This project aims to develop an underground integrated laboratory at Stawell Gold Mine in Victoria to host the Southern Hemisphere's first-ever direct-detection dark matter experiment. Following the Higgs boson discovery, the direct detection of dark matter is seen as the next major challenge for particle physics. This project sees Australian physicists team up with local and international partners in research and indus ....Australia’s first direct-detection dark matter search, at Stawell Gold Mine. This project aims to develop an underground integrated laboratory at Stawell Gold Mine in Victoria to host the Southern Hemisphere's first-ever direct-detection dark matter experiment. Following the Higgs boson discovery, the direct detection of dark matter is seen as the next major challenge for particle physics. This project sees Australian physicists team up with local and international partners in research and industry to join the search for dark matter. This Australian experiment aims to help to confirm or deny current results from Northern Hemisphere experiments. As the mine nears the end of its working life as a gold mine, this project is expected to benefit the local economy and provide opportunities for education and outreach.Read moreRead less
Nanosampling sensors for real-time embryo monitoring. The health potential of every individual is established early in life, during the period when the oocytes mature and embryos are formed. This project will develop a photonic sensing platform capable of monitoring embryos as they develop, which will lead to new insight into the earliest stages of life and improved assisted reproduction technologies.
Low power optical limiting for laser receiver protection. This project will place Australia as one of the leaders in the world in both science and technology of soft glass Photonic Band Gap Fibres, which is an enabling field of research with enormous number applications in Medicine, Defence, communication, etc. The project will develop a critical component (receiver protection) for laser range finders, which are widely being used in defence industries, therefore having national benefit in terms ....Low power optical limiting for laser receiver protection. This project will place Australia as one of the leaders in the world in both science and technology of soft glass Photonic Band Gap Fibres, which is an enabling field of research with enormous number applications in Medicine, Defence, communication, etc. The project will develop a critical component (receiver protection) for laser range finders, which are widely being used in defence industries, therefore having national benefit in terms of safeguarding Australia. The project will also be an excellent vehicle for educating young physicists and engineers in Australia. This is of national importance in itself due to the current shortage of photonics physicists.Read moreRead less
The Development of High Power Cryo-Cooled Lasers and Their Application to Remote Sensing and Other Satelite-based Data Acquisition. We shall develop high power cryo-cooled lasers which will contribute directly to the national research priorities in Frontier Technologies and Safe Guarding Australia. In particular it will contribute to photonics, to remote sensing of the environment and to space based defence and surveillance applications. It will establish Australia as a pioneer in the field and ....The Development of High Power Cryo-Cooled Lasers and Their Application to Remote Sensing and Other Satelite-based Data Acquisition. We shall develop high power cryo-cooled lasers which will contribute directly to the national research priorities in Frontier Technologies and Safe Guarding Australia. In particular it will contribute to photonics, to remote sensing of the environment and to space based defence and surveillance applications. It will establish Australia as a pioneer in the field and generate important IP. It will be of benefit to Australian and international laser and defence industry, and it will be an ideal project for educating young laser physicists and engineers, of which there currently is a serious shortage in Australia.Read moreRead less
Coherent LIDAR for Monitoring Air Pollution and Atmospheric Wind-fields. Industry, government and civil defence urgently require compact, field deployable sensors that can measure winds and monitor pollution in the atmospheric boundary layer. Without these sensors they are unable to measure and make informed decisions about windborne dispersion of industrial emissions, environmental pollutants, and chemical/biological toxins under operational conditions. The project will develop eye-safe cohere ....Coherent LIDAR for Monitoring Air Pollution and Atmospheric Wind-fields. Industry, government and civil defence urgently require compact, field deployable sensors that can measure winds and monitor pollution in the atmospheric boundary layer. Without these sensors they are unable to measure and make informed decisions about windborne dispersion of industrial emissions, environmental pollutants, and chemical/biological toxins under operational conditions. The project will develop eye-safe coherent lidar (light detection and ranging) systems that can measure wind velocities at ranges of up to 10 km with an accuracy of about 1 m/s, and can be deployed to field sites as required. The technology will be of major interest to the commercial sector.Read moreRead less
Drug Targeting to Immune Cells Using Modified Inulin Particles. Vaxine Pty Ltd is an Australian biotechnology company that has discovered specific particulate forms of inulin that are efficiently internalised by human immune cells. This project aims to exploit cell migration to injury and infection sites by attaching drugs to inulin particles creating a targeted drug delivery system. This system will transport drugs specifically to afflicted areas, reducing systemic concentrations of drugs and h ....Drug Targeting to Immune Cells Using Modified Inulin Particles. Vaxine Pty Ltd is an Australian biotechnology company that has discovered specific particulate forms of inulin that are efficiently internalised by human immune cells. This project aims to exploit cell migration to injury and infection sites by attaching drugs to inulin particles creating a targeted drug delivery system. This system will transport drugs specifically to afflicted areas, reducing systemic concentrations of drugs and hence the risks of dose related side effects. This project has potential both to improve healthcare and to encourage the growth of expertise in the biotechnology industry in Australia.Read moreRead less