Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (b ....Simulating two-phase electrodynamic flows in droplet-based microfluidic circuit elements. The knowledge, data and analysis tools developed within this project will facilitate the economical production of electrodynamically controlled integrated droplet-based microfluidic devices for critical high-demand applications such as: genome sequencing; protein evolution, synthesis and crystallisation; micro-structured pharmaceuticals; disposable devices for biomedical analysis; portable point-of-entry (biochem)security analysis devices. Hence this project is an investment in enabling technologies to benefit Australia's growing biotech, pharmaceutical and micro/nanotechnology sectors. Tangible community benefits (e.g., in improved diagnostic technologies, pharmaceuticals) will result.Read moreRead less
DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to und ....DROP DEFORMATION IN CONFINED MICROFLUIDIC GEOMETRIES. Increasingly, high technology applications in biotechnology and microtechnology industries need to process complex (non-Newtonian) fluids with dispersed particles/droplets in channels as small as several microns (microfluidics). A computational fluid dynamic model of non-Newtonian droplet deformation in microfluidic geometries will be developed, and validated using experimental measurements of the flow field in this project. The aim is to understand and quantify factors influencing droplet deformation. Coupling non-Newtonian characteristics with microfluidic geometries will allow the continuous manufacture of micro-particles of specified size and shape for existing and new applications, and will provide guidance for further extending the process to nano-particle manufacture.Read moreRead less
Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface cha ....Electro-viscous effects on pressure-driven liquid flow in microchannels. Australian biotechnology, information technology and food technology industries will benefit from the development of new tailored micro- and nano-fluidic devices for processing of non-Newtonian fluids. The efficiency of functional elements such as valves, pumps, mixers, reactors, heat exchangers can be optimised for specific fluids by understanding the coupling between the fluid properties, the device geometry, surface charge, and the numerical predictions. This understanding will complement development in related projects on non-Newtonian drop and particle formation in microfluidic flows which envisage continuous particle manufacture for novel materials possessing programmable, enhanced functional properties.Read moreRead less
Ink jet microfluidic spray drier for making high quality microencapsulated bioactive particles and nanosized particles. The proposal addresses National Research Priority area 3 (Frontier Technology). This work will develop a new, simple and effective method for producing designer smart particles that have better functional properties as well as improved uniformity for application in the food and pharmaceutical industries. The project will train graduates who will be able to make a high-level con ....Ink jet microfluidic spray drier for making high quality microencapsulated bioactive particles and nanosized particles. The proposal addresses National Research Priority area 3 (Frontier Technology). This work will develop a new, simple and effective method for producing designer smart particles that have better functional properties as well as improved uniformity for application in the food and pharmaceutical industries. The project will train graduates who will be able to make a high-level contribution to these Australian industries. This will also mark a development in Australia¡¯s nanotechnology capability in the bio-area.Read moreRead less
Supersonic flow past micro-scale particles: Industrial applications. Droplet based materials processing has developed significantly over the last decade, with applications in a wide range of industries where high-strength, light-weight materials are critical. Our research will allow for continued progress of this method, by developing accurate models to predict the cooling rate throughout the process and hence the physical properties of the finished product. Development of this knowledge will al ....Supersonic flow past micro-scale particles: Industrial applications. Droplet based materials processing has developed significantly over the last decade, with applications in a wide range of industries where high-strength, light-weight materials are critical. Our research will allow for continued progress of this method, by developing accurate models to predict the cooling rate throughout the process and hence the physical properties of the finished product. Development of this knowledge will allow for higher precision products to be produced and allow for new techniques to be developed. This information will allow for material processing in Australia to be maintained at world class levels, and for Australian industry to continue to lead the way in the production of technologically advanced materials.Read moreRead less
Special Research Initiatives - Grant ID: SR0354588
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Integrated Nanoscale Biosystems Network (INBN). The INBN will integrate high-priority research, already identified by the ARC, in materials nanoscience and engineering with nanoscale biology. The INBN will provide the means to consolidate world-class multidisciplinary Australian research groups in existing Centres of Excellence, including several Federation Fellows, into a nanobiotechnology focus. The significant outcomes of INBN are the critical mass of outstanding researchers in the nanobiosci ....Integrated Nanoscale Biosystems Network (INBN). The INBN will integrate high-priority research, already identified by the ARC, in materials nanoscience and engineering with nanoscale biology. The INBN will provide the means to consolidate world-class multidisciplinary Australian research groups in existing Centres of Excellence, including several Federation Fellows, into a nanobiotechnology focus. The significant outcomes of INBN are the critical mass of outstanding researchers in the nanobiosciences, facilitation of innovative research to produce novel intellectual property and provision of pathways into collaborative research with international scientists and industry, and the training and development of the next generation scientists for this emerging discipline.
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Advanced hierarchical materials for separation applications. The proposed project represents an international collaboration between Monash University and Fudan University and builds on the research strengths within these two Institutions in nano-materials research and applications. The proposed research will lead to a new class of materials for use in the chemical and biological industries, making their operation more efficient and permitting new separations to be performed. The research will ....Advanced hierarchical materials for separation applications. The proposed project represents an international collaboration between Monash University and Fudan University and builds on the research strengths within these two Institutions in nano-materials research and applications. The proposed research will lead to a new class of materials for use in the chemical and biological industries, making their operation more efficient and permitting new separations to be performed. The research will also pioneer new techniques for use in nano-engineering materials and falls within one of Australia's National Research Priorities: Frontier Technologies for Building and Transforming Australian Industries.Read moreRead less
Zeolitic Nanoflake-Polymer Composite Membranes for Low Energy Desalination. The desalination of seawater is becoming an important source of drinking water for Australia. The current desalination process using polymer membranes is energy-intensive. The proposed project will contribute to the development of low energy desalination technology by advancing membrane design and fabrication techniques. The use of zeolitic nanoflake-polymer composite membranes developed in this project is expected to su ....Zeolitic Nanoflake-Polymer Composite Membranes for Low Energy Desalination. The desalination of seawater is becoming an important source of drinking water for Australia. The current desalination process using polymer membranes is energy-intensive. The proposed project will contribute to the development of low energy desalination technology by advancing membrane design and fabrication techniques. The use of zeolitic nanoflake-polymer composite membranes developed in this project is expected to substantially reduce energy consumption in the desalination process. This research will produce important economic and environmental benefits by developing a green technology for fresh water production and water treatment for power generation, irrigation and other industrial uses.Read moreRead less
Novel nanostructured alloy membranes for hydrogen permeation: Advanced materials technology for renewable energy. Hydrogen purification by alloy membranes is a key technology in maintaining the greenhouse gas emission low while using the fossil fuels including coal for energy generation. However, the alloys currently available for the membrane separation are mostly based on a costly precious metal palladium, making the application of the technology limited. The proposed non-equilibrium material ....Novel nanostructured alloy membranes for hydrogen permeation: Advanced materials technology for renewable energy. Hydrogen purification by alloy membranes is a key technology in maintaining the greenhouse gas emission low while using the fossil fuels including coal for energy generation. However, the alloys currently available for the membrane separation are mostly based on a costly precious metal palladium, making the application of the technology limited. The proposed non-equilibrium material processing will enable us to fabricate novel nanocomposite niobium-based alloys to which excellent hydrogen permeation characteristics are expected with high economic viability. Successful development of the proposed alloys could enhance the competitiveness of the Australian coal industry worldwide.Read moreRead less
Plasmonic nanoparticles for probing and perturbing the spatial organisation of membrane proteins. Receptors on the surface of cells provide vital functions and represent a large fraction of drug targets. It is believed that the spatial organisation of receptors can effect their function. This project will test this hypothesis by combining nanotechnology with biophysics to watch and manipulate the spatial organisation of receptors.