The role of omega-3 fatty acids in brain mechanisms that regulate water and salt balance. The ability of mammals to survive is heavily dependent upon their ability to maintain body fluid balance. This project aims to elucidate brain mechanisms for the behavioural regulation of water and salt balance, with specific investigation of the role of dietary fatty acids within these processes. It is hypothesised that omega-3 polyunsaturated fatty acids (PUFA) affect intake of water and salt by affecti ....The role of omega-3 fatty acids in brain mechanisms that regulate water and salt balance. The ability of mammals to survive is heavily dependent upon their ability to maintain body fluid balance. This project aims to elucidate brain mechanisms for the behavioural regulation of water and salt balance, with specific investigation of the role of dietary fatty acids within these processes. It is hypothesised that omega-3 polyunsaturated fatty acids (PUFA) affect intake of water and salt by affecting the sensitivity of various receptors, or the hormones used by this body system. Omega-3 PUFA are known to play a role in regulating genes, and therefore, may also affect the production of key proteins, such as receptors, hormones or enzymes involved in the regulation of salt and water intake.Read moreRead less
Amino acids as nutrients - the molecular basis of amino acid absorption in kidney and intestine. Nutrition is a critical factor for well being and health. This is highlighted by the increase in frequency of type II diabetes and the obesity problem that all societies with a western diet face. Most studies in nutrition focus on fat and carbohydrates because of their direct involvement in obesity and diabetes. Proteins and the resulting peptides and amino acids, however, form 10-15% of our nutritio ....Amino acids as nutrients - the molecular basis of amino acid absorption in kidney and intestine. Nutrition is a critical factor for well being and health. This is highlighted by the increase in frequency of type II diabetes and the obesity problem that all societies with a western diet face. Most studies in nutrition focus on fat and carbohydrates because of their direct involvement in obesity and diabetes. Proteins and the resulting peptides and amino acids, however, form 10-15% of our nutrition. At a time where protein-rich diets are recommended to fight obesity and diabetes, it is important to understand the basis of protein absorption and metabolism. This project investigates the mechanism and mediators of amino acid absorption in kidney and intestine. Read moreRead less
Function and regulation of the Na+,K+-ATPase. The Na+,K+-ATPase is the major energy-consuming enzyme of animal cells. Its ion pumping is essential for numerous physiological functions (e.g. heart, kidney, brain). Molecular detail of its pumping mechanism is, however, lacking and its regulation is still unclear. We will use rapid reaction methods on purified enzyme in vitro to locate the rate-determining step of the enzyme cycle, determine its mechanism, investigate its regulation by sodium conce ....Function and regulation of the Na+,K+-ATPase. The Na+,K+-ATPase is the major energy-consuming enzyme of animal cells. Its ion pumping is essential for numerous physiological functions (e.g. heart, kidney, brain). Molecular detail of its pumping mechanism is, however, lacking and its regulation is still unclear. We will use rapid reaction methods on purified enzyme in vitro to locate the rate-determining step of the enzyme cycle, determine its mechanism, investigate its regulation by sodium concentration, phosphorylation and membrane composition, and isolate its charge-transporting steps. The results will have immediate impact on the understanding of the enzyme's mechanism, its metabolic control and its role in disease.Read moreRead less
Trust makers, breakers and brokers: building trust in the Australian food system. This research will compare and contrast the way that food trust is managed in Australia and the United Kingdom, with a particular focus on how trust is damaged and repaired. Using consensus-testing processes, best practice models will be developed to assist government, industry, media and consumer groups to build and maintain trust in the food supply.
Reducing the social, economic and health burden associated with obesity-related chronic diseases among socio-economically disadvantaged populations. This project will develop new methods and approaches for reducing obesity-related chronic diseases (OCDs) among socially disadvantaged populations in Australia, using prevention models. These prevention models will improve the evidence base in this field as well as inform public health policy and practice in Australia (and other industrialised count ....Reducing the social, economic and health burden associated with obesity-related chronic diseases among socio-economically disadvantaged populations. This project will develop new methods and approaches for reducing obesity-related chronic diseases (OCDs) among socially disadvantaged populations in Australia, using prevention models. These prevention models will improve the evidence base in this field as well as inform public health policy and practice in Australia (and other industrialised countries).Read moreRead less
Towards 'zero hunger': improving food relief services in Australia. This project aims to improve the effectiveness of the food relief sector in meeting the needs of >5m Australians experiencing food insecurity annually. Following an innovative co-design process with sector stakeholders and their clients, this project investigates food relief service models that satisfy emergency needs as well as address root causes of food insecurity. Expected outcomes include tested best-practice guidelines and ....Towards 'zero hunger': improving food relief services in Australia. This project aims to improve the effectiveness of the food relief sector in meeting the needs of >5m Australians experiencing food insecurity annually. Following an innovative co-design process with sector stakeholders and their clients, this project investigates food relief service models that satisfy emergency needs as well as address root causes of food insecurity. Expected outcomes include tested best-practice guidelines and auditing tools for improving, monitoring and evaluating food relief services. These will not only assist >2,500 volunteer-run organisations to deliver more nutritious foods to more people, through a more dignified, fairer and diversified service, but map a pathway for clients out of food insecurity.Read moreRead less
Youth Cultures of Eating: A Cultural Analysis of Youth Obesity, Gender, Class, Ethnicity and Generation. Australian children and teenagers rank among the most overweight in the world. While there has been ample information about healthy eating, the message does not seem to be getting through to youth. This will be the first in-depth nationwide cultural study of the effects of gender, ethnicity, class, generation and geographical location on the food consumption practices of youth. It will provid ....Youth Cultures of Eating: A Cultural Analysis of Youth Obesity, Gender, Class, Ethnicity and Generation. Australian children and teenagers rank among the most overweight in the world. While there has been ample information about healthy eating, the message does not seem to be getting through to youth. This will be the first in-depth nationwide cultural study of the effects of gender, ethnicity, class, generation and geographical location on the food consumption practices of youth. It will provide information and analysis about how primary and high school students, teachers and parents perceive the problem of youth obesity. it will also provide insights which will enable policy-makers, school authorities and health practitioners to better understand this issue.
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Food systems, urban health equity and climate stabilisation: the need for a common agenda. This research will help address two great contemporary human struggles - achieving health equity and climate stabilisation. Action concerned with economic and social policy, food systems and urban living will improve Australian and global health, and help reduce social inequity such that communities are better able both to cope with the impacts of climate change and to avert further damage to the global en ....Food systems, urban health equity and climate stabilisation: the need for a common agenda. This research will help address two great contemporary human struggles - achieving health equity and climate stabilisation. Action concerned with economic and social policy, food systems and urban living will improve Australian and global health, and help reduce social inequity such that communities are better able both to cope with the impacts of climate change and to avert further damage to the global environment. Providing an evidence base that demonstrates, for the first time, what can be done in an integrated manner, will help mobilise political and popular support for a radical break with the compartmentalised and short term approach that dominates the political agenda at state, national and global levels.Read moreRead less
Improving eating behaviours in low-income communities. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Fruit and vegetable consumption is an important part of a healthy diet. Increasing Australians' fruit and vegetable consumption will substantially cut health care costs, ....Improving eating behaviours in low-income communities. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Fruit and vegetable consumption is an important part of a healthy diet. Increasing Australians' fruit and vegetable consumption will substantially cut health care costs, improve quality of life, and boost Australia's fresh produce industry. Findings will directly inform an evidence base upon which to design appropriate policies and programs aimed at promoting fruit and vegetable consumption in socioeconomically disadvantaged groups. Read moreRead less
Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In o ....Understanding environmental drivers of socioeconomic inequalities in food consumption. The health, economic and social costs of poor nutrition are substantial. The national partnership, the Strategic Inter-governmental Nutrition Alliance, has proposed a strategy, Eat Well Australia, which aims to improve the well-being of Australians through better nutrition. Improving Australians' diet will cut health care costs, improve quality of life, and promote physical, mental and social functioning. In order to improve diet, particularly among those who are disadvantaged, a better understanding of the environmental drivers of inequalities in food consumption is required. Findings will inform the development of policies to increase the availability and accessibility of foodstuffs to supply an adequate and affordable diet for all.Read moreRead less