Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453608
Funder
Australian Research Council
Funding Amount
$579,230.00
Summary
Multifunctional confocal laser scanning microscope with time resolved and two photon imaging and fluorescence correlation capabilities. We seek to establish an Australian first confocal laser scanning microscope with time resolved imaging and fluorescence correlation spectroscopy capabilities. Its advantages include ultrasensitive detection of weak fluorescent emissions against high autofluorescent background by using fluorescence lifetime signatures, with over three orders of magnitude discrimi ....Multifunctional confocal laser scanning microscope with time resolved and two photon imaging and fluorescence correlation capabilities. We seek to establish an Australian first confocal laser scanning microscope with time resolved imaging and fluorescence correlation spectroscopy capabilities. Its advantages include ultrasensitive detection of weak fluorescent emissions against high autofluorescent background by using fluorescence lifetime signatures, with over three orders of magnitude discrimination improvement. The system will also be able to monitor binding of single molecules. These techniques will open new and exciting avenues for interdisciplinary research at the frontier between biological and physical sciences. The microscope will operate within an existing multi-user Optical Characterisation Facility supporting research of an established network of scientists in the Sydney area.Read moreRead less
Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnol ....Evolution and mechanisms of interactions in biofilm communities. This project aims to study the long-term experimental evolution of a mixed species bacterial biofilm community. This project expects to gain understanding of the genetic and physiological basis of community evolution. Expected outcomes of this project will be an understanding of how synthetic communities evolve. This will significantly benefit the use of synthetic communities relevant to fields such as antibiotic design, biotechnology, bioremediation, and synthetic biology where evolution can be inhibited or exploited, respectively.Read moreRead less
ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use ....ARC Centre of Excellence - Structural and Functional Microbial Genomics. The research falls under the National Research Priority Frontier Technologies for Building and Transforming Australian Industries, with the priority goal of frontier technologies. The research has commercial applications, such as the development of novel antimicrobials and vaccines, with potentially enormous impact in the biotechnology area of biomedical health and the primary industries. In addition, the project will use state-of-the-art technology, including use of synchrotron radiation at the Monash-based Australian Synchrotron facility from 2007.Read moreRead less
ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes i ....ARC Centre for Structural & Functional Microbial Genomics. Australian Primary Industry will benefit from a team of experts in microbial genetics, bioinformatics and protein structure and function undertaking integrated studies on microbial genomics and phenomics that are focused on fundamental biological processes and host/pathogen interactions. Whole genome expression and protein profiling will be used to characterise genes whose expression is altered in the infected host and to analyse genes involved in the control of key cellular processes. The Centre will also determine the shapes of key molecules and their interactions. Practical outcomes will include new veterinary vaccines and the identification of novel antimicrobial targets.Read moreRead less
Determinants of substrate preferences and environmental applications of the copper membrane monooxygenases. The project aims to improve sustainability of environmental problems related to methane emissions, nitrogen cycling and pollution. We are developing tools targeting microbial genes correlated to all these issues. Data from these tests provides the information needed for monitoring environmental health and development of sustainable solutions.
Special Research Initiatives - Grant ID: SR0354787
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 biorem ....Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 bioremediation and algal/bacterial systems for the bioremediation of contaminated soils. This will be achieved by applying research on photosynthetic light utilisation efficiency and carbon fixation, chlorophyll fluorescence, biochemistry of secondary metabolites, molecular biology and photobioreactor design and engineering, informed by an understanding of the ecology of these algae.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100032
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
A ToF-SIMS facility for elemental and isotopic imaging of ultra-fine features for researchers in east Australia. A time of flight secondary ion mass spectrometer facility for elemental and isotopic imaging of ultra-fine features: Microbiology has long been an area of strength in Australian science. With recent technological advances microbiology has entered a new golden age unveiling an extraordinary level of diversity and the central role of microbes in global biogeochemistry. The 'omics' era i ....A ToF-SIMS facility for elemental and isotopic imaging of ultra-fine features for researchers in east Australia. A time of flight secondary ion mass spectrometer facility for elemental and isotopic imaging of ultra-fine features: Microbiology has long been an area of strength in Australian science. With recent technological advances microbiology has entered a new golden age unveiling an extraordinary level of diversity and the central role of microbes in global biogeochemistry. The 'omics' era is generating endless hypotheses regarding geochemical processes carried out by microbes and this necessitates the application of advanced technologies to generate empirical support. Time of flight secondary ion mass spectrometry has emerged as a key tool to unravel elemental cycling carried out by microorganisms in mixed species communities in contexts ranging from terrestrial to marine ecology and from groundwater bioremediation to biogas production biotechnologies.Read moreRead less
ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functi ....ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functional materials, ii) high-tech IT/communications/sensing materials, iii) materials solutions for manufacturing, iv) materials for a sustainable Australia, and v) emerging materials technologies. Key programs will promote interdisciplinary workshops and early career researcher interactions.Read moreRead less
Special Research Initiatives - Grant ID: SR0354512
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Network Asia: Maximizing Australia's National Capacity in Inter-Disciplinary Research on Asia. Australia has an international reputation for innovative and high impact research into the states, societies, and economies of Asia.
The Initiative will survey the volume, range, impact, and international status of Asian area research in Australia, identify themes with high potential for achieving significant outcomes through transnational research and research-training, and develop a strategy for m ....Network Asia: Maximizing Australia's National Capacity in Inter-Disciplinary Research on Asia. Australia has an international reputation for innovative and high impact research into the states, societies, and economies of Asia.
The Initiative will survey the volume, range, impact, and international status of Asian area research in Australia, identify themes with high potential for achieving significant outcomes through transnational research and research-training, and develop a strategy for maximizing national research capacity in targeted areas through a national inter-disciplinary network for Asia-area research - Network Asia.
Outcomes include a published report on the state of the field and a strategic plan for a viable and sustainable research network.
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Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less