MICROFABRICATED DEVICES: A SIGNIFICANT ADVANCE FOR THE DETECTION AND MOLECULAR ANALYSES OF CIRCULATING CANCER CELLS?
Funder
National Health and Medical Research Council
Funding Amount
$422,107.00
Summary
Using advanced microfabrication concepts, this project aims to develop a platform technology able to capture tumour cells circulating in the blood of cancer patients. Although present only in extremely small numbers, these cells provide invaluable insights into the pathophysiology of the disease and consequently provide vital diagnostic and prognostic information. Molecular analyses of these cancer cells could ultimately enable the design of improved and personalized cancer treatment.
Industrial Transformation Research Hubs - Grant ID: IH170100013
Funder
Australian Research Council
Funding Amount
$2,962,655.00
Summary
ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed device ....ARC Research Hub for Digital Enhanced Living. The ARC Research Hub for Digital Enhanced Living aims to address the growing challenges of aging people living in their own home or residential care. This will be through inventing new personalised medical technologies through an innovative approach, with a multi-disciplinary team leveraging diverse expertise. An enhanced capacity to create and deploy fit-for-purpose personalised health solutions will result in revenues from new and repurposed devices, analytics and integration platforms. New jobs and improved care will see cost reductions, better use of resources and enhanced mental, physical and social well-being.Read moreRead less
Numerical simulation of seismic waves in the regional and global earth with 3D Gaussian quadrature grids. The ability to realistically model the propagation of seismic waves through the global 3D earth, taking account of all internal and surface complexity, is extremely important for predicting the response to earthquakes and imaging the interior structure. This will lead to fundamental new knowledge on Earth constitution and heterogeneity, and will have spin-off benefits in others areas such as ....Numerical simulation of seismic waves in the regional and global earth with 3D Gaussian quadrature grids. The ability to realistically model the propagation of seismic waves through the global 3D earth, taking account of all internal and surface complexity, is extremely important for predicting the response to earthquakes and imaging the interior structure. This will lead to fundamental new knowledge on Earth constitution and heterogeneity, and will have spin-off benefits in others areas such as exploring for oil and minerals, and better understanding of seismic hazard. The numerical modelling and seismic data analysis will be done on a supercomputer, thus providing important training for research students. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100001
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation ....Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation at sub-micron scales and cryogenic temperatures, under bio-simulated environments, down to single pixel resolution, with parallel imaging and spectroscopy, and of fluids and biomaterials. The instrumentation will include cryogenic sub-micron photoluminescence and micro-Raman spectroscopy, single pixel optical and dark field spectroscopy, continuous wave terahertz time-domain spectroscopy, wide wavelength microscopic spectroscopy, and temperature-jump kinetics spectroscopy. It is expected that these complementary instruments will accelerate research in materials and devices for plasmonics, nanoelectronics, biomedicine, biochemistry, security, and forensic science.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longe ....Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longevity.Read moreRead less
Special Research Initiatives - Grant ID: SR0354735
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Network on Microelectronics, Optoelectronics and Microelectromechanical Systems. The Network will encompass semiconductor microelectronics, optoelectronics, sensors and microelectromechanical systems (MEMS). Fundamental research in these areas enables the technological advances that underpin rapidly developing industries such as information and telecommunications technologies, defence, aerospace, medicine, and remote sensing. Exciting challenges exist in designing new devices that exp ....Australian Network on Microelectronics, Optoelectronics and Microelectromechanical Systems. The Network will encompass semiconductor microelectronics, optoelectronics, sensors and microelectromechanical systems (MEMS). Fundamental research in these areas enables the technological advances that underpin rapidly developing industries such as information and telecommunications technologies, defence, aerospace, medicine, and remote sensing. Exciting challenges exist in designing new devices that exploit unique semiconductor systems and technologies. By sharing capabilities and resources (both capital and human), the network will enable the issues associated with such novel materials and devices to be addressed in a targeted manner. The network will also guarantee the ongoing future of research in the area by actively involving early career researchers and postgraduate students.Read moreRead less
Seismic wave modelling and inversion for the most general 3-D anisotropic media. Advanced numerical techniques will be developed and applied to simulate the kinematic and dynamic properties of seismic wave propagation in a complex three-dimensional Earth, involving topography, heterogeneity and the most general anisotropy defined by 21 spatially-dependent elastic moduli. We will develop 2D/3D ray-tracing methods for anisotropic traveltime tomography, 2.5D/3D frequency-domain spectral element met ....Seismic wave modelling and inversion for the most general 3-D anisotropic media. Advanced numerical techniques will be developed and applied to simulate the kinematic and dynamic properties of seismic wave propagation in a complex three-dimensional Earth, involving topography, heterogeneity and the most general anisotropy defined by 21 spatially-dependent elastic moduli. We will develop 2D/3D ray-tracing methods for anisotropic traveltime tomography, 2.5D/3D frequency-domain spectral element methods for full waveform inversion of observational data, and make all these techniques applicable for subsurface imaging under various classes of anisotropy in the Earth. Results will be important for petroleum exploration as well as earthquake seismology and probing the structure of the Earth's deep interior.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100238
Funder
Australian Research Council
Funding Amount
$426,087.00
Summary
Integrated silicon carbide nanosensors for monitoring extreme environment. This project aims to develop a highly sensitive and reliable sensing platform for structural health monitoring in harsh environments, encompassing high temperature, corrosion, and shock. These conditions have been posing several technical challenges to sensing and electronic devices. The project elucidates the piezoresistive and thermoresistive effects in silicon carbide nanowires, which are the building blocks of robust ....Integrated silicon carbide nanosensors for monitoring extreme environment. This project aims to develop a highly sensitive and reliable sensing platform for structural health monitoring in harsh environments, encompassing high temperature, corrosion, and shock. These conditions have been posing several technical challenges to sensing and electronic devices. The project elucidates the piezoresistive and thermoresistive effects in silicon carbide nanowires, which are the building blocks of robust mechanical and thermal sensors used in extreme conditions. The findings from this project expect to provide Australia with the cutting-edge expertise necessary for developing next-generation monitoring systems in the extreme environments of the oil/gas transportation, mining, automobile, and space exploration industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100175
Funder
Australian Research Council
Funding Amount
$347,070.00
Summary
Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used ....Three-dimensional additive bio-fabrication facility: printing bioprinters. This project aims to develop bioprinting systems that will provide new insights into fundamental biological processes. The 3D Additive Bio-Fabrication Facility - Printing Bioprinters capability will use 3D polymer and metal additive manufacturing technologies to create the next generation of bioprinting methodologies and 3D fabrication tools. It is the aim that these customised additive manufacturing systems will be used to produce structures wherein living cells are spatially organised in combination with appropriate biomaterials and bioactive components, such as drugs or growth factors, in order to influence subsequent biological behaviour.Read moreRead less