Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessmen ....Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessment of the distributional impact of a wide range of possible reforms, including how the outcomes of any policy change will affect disadvantaged sections of our society, whether different generations will be fairly treated, and the impact by gender.Read moreRead less
Modelling the lifetime social and economic impacts of fragile x syndrome and the benefits of early diagnosis and intervention. This project falls within the National Research Priority, promoting and maintaining good health, through a healthy start to life and strengthening of social and economic outcomes over the course of life. Fragile X is a group of associated genetic disorders affecting individuals across generations. It is the most common identifiable cause of inherited intellectual disabil ....Modelling the lifetime social and economic impacts of fragile x syndrome and the benefits of early diagnosis and intervention. This project falls within the National Research Priority, promoting and maintaining good health, through a healthy start to life and strengthening of social and economic outcomes over the course of life. Fragile X is a group of associated genetic disorders affecting individuals across generations. It is the most common identifiable cause of inherited intellectual disability. About 1 in 4000 males and 1 in 8000 females have Fragile X, but up to 1 in 250 females are carriers. For the first time in Australia, this study will reveal the social and economic impacts on the individual, on their family members who are often the lifelong carers, and on the Australian community, and show how these impacts may be minimised through early intervention.Read moreRead less
Improving Medication Safety In Seniors: A Cross-Jurisdictional Linkage Project
Funder
National Health and Medical Research Council
Funding Amount
$636,717.00
Summary
The project will identify priorities for tackling the current epidemic of hospitalisation of Australians aged 65+ years due to side effects of their medications. Two different groups of medications will be investigated. The first will be the prescribed drugs most often recorded as causes of hospital stay, including those taken to stop blood clotting, for high blood pressure and other cardiovascular problems, for rheumatism or strong pain relief, anti-cancer drugs and steroids. The study will exa ....The project will identify priorities for tackling the current epidemic of hospitalisation of Australians aged 65+ years due to side effects of their medications. Two different groups of medications will be investigated. The first will be the prescribed drugs most often recorded as causes of hospital stay, including those taken to stop blood clotting, for high blood pressure and other cardiovascular problems, for rheumatism or strong pain relief, anti-cancer drugs and steroids. The study will examine which of these drugs taken under what circumstances has the highest risk, so prevention can be better targeted. The study will investigate if adequate laboratory monitoring of the anti- clotting drugs is taking place and whether the guidelines should be updated. The second group will be 68 medications that should be avoided in seniors according to an international expert panel. The research will see how often these 'inappropriate medications' are still prescribed in the Australian setting, and the size of their contributions to unplanned hospital stays. The researchers suspect that this problem is much larger than immediately apparent from routine statistics, because many of the side effects of inappropriate medications are non-specific, such as confusion, drowsiness or difficulty standing up, thus putting seniors at risk of falls and neglect of other aspects of their health. The study will use a unique and new Australian research facility, which has brought together health data on the entire population of WA from both the State and Commonwealth levels, including information on pharmaceuticals, Medicare use, hospital stays and deaths. The facility works in such a way as to preserve patient and GP privacy. A strong feature of this research will be the degree of involvement of a representative and voluntary group of older Australian patients who attend GP clinics, and the GPs themselves, in advising the researchers on what's important to consumers and GPs.Read moreRead less
Patient and nurse outcomes and the cost of nurses' turnover in Australian hospitals. An adequate supply of nurses is fundamental to all of the National Health Priority disease areas where quality care cannot be delivered without an adequate number of motivated nurses. Designing cost-effective methods of retaining nurses requires understanding reasons why they leave the workforce and the impact this has on patient care and system costs. The findings will assist policy makers and workforce planner ....Patient and nurse outcomes and the cost of nurses' turnover in Australian hospitals. An adequate supply of nurses is fundamental to all of the National Health Priority disease areas where quality care cannot be delivered without an adequate number of motivated nurses. Designing cost-effective methods of retaining nurses requires understanding reasons why they leave the workforce and the impact this has on patient care and system costs. The findings will assist policy makers and workforce planners at both local and national levels, to design strategies to effectively recruit and retain nurses as demands for health care and market competition for staff both increase.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100087
Funder
Australian Research Council
Funding Amount
$328,075.00
Summary
Internal wave breaking and mixing in the ocean. This project aims to quantify turbulent mixing in the ocean using ultra-high-resolution numerical modelling. Turbulent mixing is caused by internal waves which transport energy from the ocean boundaries into the interior, where they drive mixing of cold, deep water with warmer water above. This mixing is crucial to the ocean circulation which controls the storage of heat and carbon in the ocean, but is inadequately represented in current climate mo ....Internal wave breaking and mixing in the ocean. This project aims to quantify turbulent mixing in the ocean using ultra-high-resolution numerical modelling. Turbulent mixing is caused by internal waves which transport energy from the ocean boundaries into the interior, where they drive mixing of cold, deep water with warmer water above. This mixing is crucial to the ocean circulation which controls the storage of heat and carbon in the ocean, but is inadequately represented in current climate models. The anticipated outcome of the project is an enhanced, global-ocean model incorporating an accurate description of turbulent mixing. This should provide significant benefits to the Australian community by improving the accuracy of future climate predictions.Read moreRead less
Eddy-resolving global ocean-sea ice modelling. Eddy-resolving global ocean-sea ice modelling. This project aims to develop a world-class global ocean-sea ice model framework through a nationwide consortium. The resulting high resolution models are expected to provide the foundation for the next decade of Australian ocean-sea ice modelling capacity. This research should lead to improved ocean and sea ice prediction, ocean reanalyses, and climate projections, enhancing Australia's capacity to pred ....Eddy-resolving global ocean-sea ice modelling. Eddy-resolving global ocean-sea ice modelling. This project aims to develop a world-class global ocean-sea ice model framework through a nationwide consortium. The resulting high resolution models are expected to provide the foundation for the next decade of Australian ocean-sea ice modelling capacity. This research should lead to improved ocean and sea ice prediction, ocean reanalyses, and climate projections, enhancing Australia's capacity to predict the ocean state on timescales of days to decades. This is expected to yield efficiencies in shipping, marine search and rescue and naval operations, and increase the accuracy of projected future changes in climate, sea level, ocean ecosystems and the cryosphere.Read moreRead less
Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilit ....Building Australia's next-generation ocean-sea ice model. Ocean and sea ice models are used for predicting future ocean and climate states, and for climate process research. This project aims to bring the next generation of ocean-sea ice models to Australia and configure the models for our local priorities. The ultimate goal is to create a new coupled ocean-sea ice model for Australia that includes surface waves and biogeochemistry. The model will be optimised and evaluated on Australian facilities, and released for community use. These developments underpin future ocean state forecasts, sea ice forecasts, wave forecasts, decadal climate prediction and climate process studies. The project will benefit search and rescue, Defence and shipping operations, and will enhance future climate projections.Read moreRead less
Understanding leaf water isotope composition. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for paleoclimatologists and plant scientists to constrain global carbon cycles. Leaf water stable isotopes influence the isotope compositions of atmospheric oxygen, carbon dioxide and water vapour, and impart an evaporative signal on the isotope composition of plant organic material. These isotope signals have been used to constrain global carbon and water c ....Understanding leaf water isotope composition. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for paleoclimatologists and plant scientists to constrain global carbon cycles. Leaf water stable isotopes influence the isotope compositions of atmospheric oxygen, carbon dioxide and water vapour, and impart an evaporative signal on the isotope composition of plant organic material. These isotope signals have been used to constrain global carbon and water cycles and reconstruct past climates. This project aims to quantify variation in leaf water isotopes and develop mechanistic models for use by paleoclimatologists, plant scientists and to constrain global carbon cycles and develop accurate models of leaf water isotopes to reduce uncertainty in climate models.Read moreRead less
Identifying Novel Antimalarial Targets Using ENU Mutagenesis In The Mouse
Funder
National Health and Medical Research Council
Funding Amount
$760,170.00
Summary
Malaria is estimated to cause 1.2 million deaths per year. The malarial parasite has developed resistance to most drugs and new drugs are needed. We aim to mimic the protective red blood cell diseases common in human populations in malarial endemic areas by identifying host targets that are important in parasite growth.
ARC Centre of Excellence for the Weather of the 21st Century. ARC Centre of Excellence for the Weather of the 21st Century. This Centre aims to determine how Australia’s weather is being reshaped by climate change. Through a fusion of innovative analyses of observations and fundamental science advances, alongside the development of ultra-high resolution climate models, the Centre looks to address climate science’s grand challenge in anticipating the likely weather patterns of a warmer world. The ....ARC Centre of Excellence for the Weather of the 21st Century. ARC Centre of Excellence for the Weather of the 21st Century. This Centre aims to determine how Australia’s weather is being reshaped by climate change. Through a fusion of innovative analyses of observations and fundamental science advances, alongside the development of ultra-high resolution climate models, the Centre looks to address climate science’s grand challenge in anticipating the likely weather patterns of a warmer world. The Centre strives to transform climate research by focussing on what matters most to making critical adaptation and mitigation decisions – weather change. The Centre aspires to provide Australia with the knowledge, technology, and human capital for robust evidence-based decision-making in response to future weather changes in our region and to harness weather as a resource.Read moreRead less