What Do Australians Think About Privacy And Participation In Epidemiological Research?
Funder
National Health and Medical Research Council
Funding Amount
$443,015.00
Summary
There is very little research available, in Australia or internationally, about what the general public considers privacy to be; or how important privacy protection is in the context of high and low risk epidemiological studies. We also know little about what affects willingness to participate in epidemiological research. Our research will provide an evidence base, and develop resources for the legislature, the NHMRC, ethics committees and researchers.
Osteoporosis is a major and increasing public health problem. Fracture, the ultimate consequence of osteoporosis is associated with significant morbidity, mortality and economic costs. The Dubbo Osteoporosis Epidemiology Study, starting in 1989, with over 2000 women and men, is one of the longest running epidemiological studies in osteoporosis worldwide. It has been at the forefront of epidemiological advances in osteoporosis. It has identified osteoporotic fracture risks including low bone dens ....Osteoporosis is a major and increasing public health problem. Fracture, the ultimate consequence of osteoporosis is associated with significant morbidity, mortality and economic costs. The Dubbo Osteoporosis Epidemiology Study, starting in 1989, with over 2000 women and men, is one of the longest running epidemiological studies in osteoporosis worldwide. It has been at the forefront of epidemiological advances in osteoporosis. It has identified osteoporotic fracture risks including low bone density and bone loss, muscle weakness and postural instability, as well as the extent of the problem in men, and the significant costs, ill-heath and mortality associated with fracture. Despite the clarification of risk factors over the past decade, there are significant gaps in knowledge about osteoporosis, particularly in the accurate prediction of fracture risk and in identification of factors related to fracture-associated mortality and survival post fracture. Although bone density is one of the best predictors of fracture risk, it incompletely discriminates between those who will fracture from those who will not. Although a number of clinical risk factors, and other measures of bone strength, such as quantitative ultrasound and geometry, have been shown to be independent predictors of fracture risk, it is not clear that these measures can be integrated with BMD to improve fracture prediction. The aim of the current study, is to develop and validate models using bone density, other measures of bone strength and clinical parameters that will more accurately predict fracture risk and mortality following fracture in older men and women. The more precise identification of those at high risk of fracture and at risk for poor outcomes following fracture will provide a rational basis for the development of more cost effective interventions for prevention of fracture and its associated morbidity and mortality.Read moreRead less
Molecular Epidemiology Of Cancers Of The Pancreas And Skin.
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Pancreatic cancer is the 4th most common cause of cancer death in Australia. The causes of this disease are largely unknown. I am conducting research designed to understand genetic and environmental causes of pancreatic cancer. Skin cancer occurs more frequently than any other cancer in Australia. Sunlight is the most common cause but it is also possible that human papilloma viruses may play a role. If high risk types of this virus can be identified, new preventive strategies may be developed.
Metabolic And Hormonal Pathways In Gynecological Cancer - Epidemiological Studies Of Risk And Survival
Funder
National Health and Medical Research Council
Funding Amount
$288,275.00
Summary
Metabolic and hormonal factors probably play a role in a womans chance of developing and surviving gynecological cancer, but the exact mechanisms are unclear. This project will use questionnaire information, blood and tumour samples of over 5,000 Australian women to examine the mechanisms leading to cancer development and survival among women with uterine and ovarian cancer, the two commonest female reproductive cancers. Results will help plan primary prevention strategies and care.
Trials To Prevent The Transmission And Complications Of Sexually Transmitted Infections, Including HIV
Funder
National Health and Medical Research Council
Funding Amount
$306,123.00
Summary
Sexually transmitted infections (STIs) are important causes of illness in some sectors of the community. Even though they can be effectively prevented and treated, many health services do not give them priority. This research project will study ways in which general practitioners can better diagnose and treat STIs. We will carry out trials that compare new approaches to supporting doctors in this area, that involve a mixture of training, reminders and technical support as needed.
SES And Injury In Children: A Cohort Study To Identify And Measure The Effects Of Preventable Mediating Factors
Funder
National Health and Medical Research Council
Funding Amount
$360,505.00
Summary
While changing an individual or group SES is at best a long term and challenging social objective, proximal risk factors for injury can be more readily modified. Once the proximal risk factor differential across SES groups has been adequately delineated, then the possibility arises for targeted public health intervention to redress the SES differential in the incidence of injury. The sophistication of the proposed modeling will result in a good assessment of the best point to target.