The multiplexed diagnosis of arbovirus infections using combinatorial probes. Viruses that cause serious diseases such as hemorrhagic fever or encephalitis must be quickly identified. Diagnostic tests based on DNA hybridisation are accurate and can be rapid but they are expensive. We will test a method for simplifying DNA tests and increasing their capabilities. DNA probes for detecting arboviruses will be designed at the ANU using new bioinformatic methods and their reliability will be model ....The multiplexed diagnosis of arbovirus infections using combinatorial probes. Viruses that cause serious diseases such as hemorrhagic fever or encephalitis must be quickly identified. Diagnostic tests based on DNA hybridisation are accurate and can be rapid but they are expensive. We will test a method for simplifying DNA tests and increasing their capabilities. DNA probes for detecting arboviruses will be designed at the ANU using new bioinformatic methods and their reliability will be modelled using all the available genetic information. Computer predictions will be experimentally tested in the PANBIO laboratory by using the probes to detect viral nucleic acids. The influence of virus genome complexity will be investigatedRead moreRead less
Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health ....Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health of adults with ID that has been undertaken internationally to date. The population will cover the age span of late adolescence (16 years) through the transition to adult life then through to the elderly. The research will establish the prevalence and nature of mental illness and potential risk factors in a large representative population of adults with ID.Read moreRead less
Developing new methods to retrieve and analyse preserved genetic information. This project will position Australia at the leading edge of research into preserved DNA, and will use innovative molecular biology approaches to develop a range of new forensic, archaeological and medical applications. It will build Australian knowledge and scientific capacity by developing core expertise and training personnel in areas important for biosecurity, customs and quarantine, forensics/counter-terrorism, and ....Developing new methods to retrieve and analyse preserved genetic information. This project will position Australia at the leading edge of research into preserved DNA, and will use innovative molecular biology approaches to develop a range of new forensic, archaeological and medical applications. It will build Australian knowledge and scientific capacity by developing core expertise and training personnel in areas important for biosecurity, customs and quarantine, forensics/counter-terrorism, and studies of climate change. It will also create and foster research innovation in molecular biology with spin-offs for evolution, archaeology, medical and conservation biology research, and will also encourage involvement with the rapidly expanding field of genomics and bioinformatics.Read moreRead less
Architectural glass related injury: implications for improving public safety. The immediate benefit of the project is information for government, the building and furniture industries, regulators, and the community to underpin interventions to prevent architectural and furniture glass injury. A major longer term benefit is to provide the crucial injury and glass data for future conduct of the other two phases of the planned research program, namely, glass performance testing and simulated human- ....Architectural glass related injury: implications for improving public safety. The immediate benefit of the project is information for government, the building and furniture industries, regulators, and the community to underpin interventions to prevent architectural and furniture glass injury. A major longer term benefit is to provide the crucial injury and glass data for future conduct of the other two phases of the planned research program, namely, glass performance testing and simulated human-glass impact studies. These future studies will provide the scientific evidence for review of the Standards for architectural glass for application to the building, design and construction industry to increase safety for the Australian community. Read moreRead less
Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia ....Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia from invasive diseases. There is an urgency to undertake our research because global environmental change and increasing movements of people (particularly military personnel) from overseas regions where these diseases are endemic is increasing the vulnerability of northern Australia to the (re)establishment of mosquito borne diseases.Read moreRead less
The transition from secondary school to adulthood: Experiences and life outcomes for youth with an intellectual disability and their families. This project seeks to explore the challenges faced and outcomes achieved by students with an intellectual disability as they move from secondary school into adult life. The study will investigate the factors at an individual, educational, family, and societal level which positively and adversely affect outcomes for young people with an intellectual disab ....The transition from secondary school to adulthood: Experiences and life outcomes for youth with an intellectual disability and their families. This project seeks to explore the challenges faced and outcomes achieved by students with an intellectual disability as they move from secondary school into adult life. The study will investigate the factors at an individual, educational, family, and societal level which positively and adversely affect outcomes for young people with an intellectual disability and their families. Family impacts can include significant loss of income as parents may have to cease employment to care for their young adult who has limited employment or day placement options. Gaining the knowledge to minimise the disruption to family life, which often occurs at this time of transition, will lead to strengthening Australia's social and economic fabric.Read moreRead less
Space development of the HDLT Australian Plasma Thruster. The collaboration between the ANU research group and ASTRIUM/EADS, the largest European aerospace company, is a unique opportunity for Australia to capitalize on the new discovery of the Helicon Double Layer Thruster made at the ANU. This will allow the Australian space community to stay abreast of international developments in space propulsion and to be with the for-runners of this new technology.
ANU will have direct access to ASTRIUM ....Space development of the HDLT Australian Plasma Thruster. The collaboration between the ANU research group and ASTRIUM/EADS, the largest European aerospace company, is a unique opportunity for Australia to capitalize on the new discovery of the Helicon Double Layer Thruster made at the ANU. This will allow the Australian space community to stay abreast of international developments in space propulsion and to be with the for-runners of this new technology.
ANU will have direct access to ASTRIUM/EADS via the relationships developed in this project putting Australia in the enviable position of being an insider in future space developments concerning plasma thrusters and space technology in general.Read moreRead less
Improving employment outcomes for Australians with disability. This project aims to provide evidence about how to improve employment outcomes for people with disability. Nearly one in five adult Australians have a disability and just over half of these are in the labour force; a modest increase in employment rates will have significant social and economic benefits for people with disability and society. By collecting longitudinal quantitative (survey) and qualitative (interview) data at three ti ....Improving employment outcomes for Australians with disability. This project aims to provide evidence about how to improve employment outcomes for people with disability. Nearly one in five adult Australians have a disability and just over half of these are in the labour force; a modest increase in employment rates will have significant social and economic benefits for people with disability and society. By collecting longitudinal quantitative (survey) and qualitative (interview) data at three time points from over 1500 jobseekers with disability, critical information should be gained about how the characteristics of employment services, workplaces and jobseekers contribute to sustainable, meaningful employment for people with disability.Read moreRead less
What role does wildlife play in emergency disease? The case of the feral pig. Wildlife populations have been responsible for many disease emergencies with economic and human health impacts, but our current understanding limits their management. This project focuses on the feral pig, an introduced wildlife species. It will develop an understanding of disease spread in feral pigs and from feral pigs to cattle. Using feral pig disease genetics, climate and environmental data, disease spread models ....What role does wildlife play in emergency disease? The case of the feral pig. Wildlife populations have been responsible for many disease emergencies with economic and human health impacts, but our current understanding limits their management. This project focuses on the feral pig, an introduced wildlife species. It will develop an understanding of disease spread in feral pigs and from feral pigs to cattle. Using feral pig disease genetics, climate and environmental data, disease spread models will be developed. These models will be used to better manage emergency disease outbreaks in feral pigs and other wildlife species. This project will deliver practical outcomes, such as the best method of discovering disease and the most effective methods to control emergency animal diseases in wildlife and domestic animals.Read moreRead less
Identifying and controlling the source of Campylobacter and Salmonella in Australia. This project will identify the source of foodborne illnesses due to Salmonella and Campylobacter in order to inform food regulatory policy. The ultimate aim is to reduce the amount of foodborne disease in Australia.