Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.
Driving Change: Using Emergency Department Data To Reduce Alcohol-related Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,468,026.00
Summary
The proposed project is a system change within partner emergency departments, providing them the information and tools to act on both risky alcohol consumption in individual patients and the sources of alcohol in the community which cause the harm they experience. Most importantly, the proposed public health interventions act as a tool for emergency departments to regularly raise awareness with the public and policymakers regarding the impact of alcohol on patients, clinicians and hospitals.
New tools to detect ecological effects of contaminants in estuaries. Identifying risks to estuarine environments from pollutants is difficult for environmental managers, who must choose between laboratory toxicity testing that is precise, but hard to generalise to field situations, and more realistic field-based monitoring, which is expensive, with a high signal to noise ratio. New molecular techniques may provide more options. Metabolomics can provide insights into the health of animals, and ec ....New tools to detect ecological effects of contaminants in estuaries. Identifying risks to estuarine environments from pollutants is difficult for environmental managers, who must choose between laboratory toxicity testing that is precise, but hard to generalise to field situations, and more realistic field-based monitoring, which is expensive, with a high signal to noise ratio. New molecular techniques may provide more options. Metabolomics can provide insights into the health of animals, and ecogenomics offers a way to rapidly assess the composition of an ecological community. These techniques offer great promise, but they must be cross-validated against existing methods to derive the best ’toolbox’. Working with Melbourne Water and CSIRO the investigators aim to do this using demonstration estuaries in Victoria.Read moreRead less
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100155
Funder
Australian Research Council
Funding Amount
$648,000.00
Summary
NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an i ....NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an integrated software and hardware system called NanoMin which incorporates a spectral deconvolution engine combined with a mineral spectra database. A key limitation in understanding complex materials is sub-micron to nanometer scale spatial variability of mineralogical phases. Imaging and quantifying these phases is now possible with the NanoMin system. This promises to open up petrological, geobiological, and materials science research in complex fine-grained materials.Read moreRead less
Modern statistical methods for clustering community ecology data. This project will develop statistical methods and software for clustering community ecology data, and use them to analyse systematic survey and citizen science program data collected along the Great Barrier Reef. By doing so, the project will address the dearth of statistical classification techniques for high-dimensional, multi-response data with complex relationships. When the resultant clustering methods are used to construct b ....Modern statistical methods for clustering community ecology data. This project will develop statistical methods and software for clustering community ecology data, and use them to analyse systematic survey and citizen science program data collected along the Great Barrier Reef. By doing so, the project will address the dearth of statistical classification techniques for high-dimensional, multi-response data with complex relationships. When the resultant clustering methods are used to construct bioregions and characterise species’ environmental responses, they should significantly enhance evaluations of the impact of human activity and environmental change on coral diversity. Ultimately, these evaluations can underpin future decisions in the conservation and management of the Great Barrier Reef.Read moreRead less
Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecologic ....The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecological impacts of industry development. Important benefits of the project include information and tools for streamlining development approvals and accurately assessing risks to threatened species to improve outcomes for both our economy and our natural environment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100146
Funder
Australian Research Council
Funding Amount
$320,000.00
Summary
The marine productivity buoy: a multi-parametric underwater profiler . The marine productivity buoy: a multi-parametric underwater profiler:
The marine productivity buoy is an innovative multi-parametric moored underwater profiler that would provide key information on phytoplankton primary productivity (PP), phytoplankton blooms, and water quality in coastal waters around Australia. The aim is to better understand changes in phytoplankton PP and abundance by synergistically using observations ....The marine productivity buoy: a multi-parametric underwater profiler . The marine productivity buoy: a multi-parametric underwater profiler:
The marine productivity buoy is an innovative multi-parametric moored underwater profiler that would provide key information on phytoplankton primary productivity (PP), phytoplankton blooms, and water quality in coastal waters around Australia. The aim is to better understand changes in phytoplankton PP and abundance by synergistically using observations from the new facility made several times a day from the surface to the seafloor, and spatially extended surface observations from Earth-orbiting ocean colour satellites. Anticipated outcomes are more accurate phytoplankton PP estimates and water quality parameters in Australian coastal waters in support to research and to monitoring of these critical environments.Read moreRead less
How effective are environmental flows? Novel approaches for monitoring and assessing ecological responses to large-scale flow alteration. Australia has begun a multi-billion dollar program to return water to stressed rivers as environmental flows. However, during times of unprecedented water scarcity, such an investment in the environment can be controversial because the ecological benefits of released water are mostly poorly understood. This project will demonstrate the effectiveness of environ ....How effective are environmental flows? Novel approaches for monitoring and assessing ecological responses to large-scale flow alteration. Australia has begun a multi-billion dollar program to return water to stressed rivers as environmental flows. However, during times of unprecedented water scarcity, such an investment in the environment can be controversial because the ecological benefits of released water are mostly poorly understood. This project will demonstrate the effectiveness of environmental flows, and promote greater understanding of the links between flow patterns and river health. The project will build upon existing knowledge to create a sound framework for planning, monitoring, and evaluation of environmental watering decisions across regional Australia, greatly improving our ability to sustainably manage rivers into the future.Read moreRead less