Probiotic Prawn Oral Immunotherapy (ProPIT) For Treatment Of Prawn Allergy
Funder
National Health and Medical Research Council
Funding Amount
$1,865,369.00
Summary
A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.
Early Career Industry Fellowships - Grant ID: IE230100437
Funder
Australian Research Council
Funding Amount
$417,237.00
Summary
Nanobubbles for effective and energy efficient water treatment. This project aims to produce new knowledge for developing ozone nanobubbles as a technological option for the water industry where commercially suitable technologies are unavailable. Australian water utilities have identified two key challenges: destruction of micropollutants and natural organic matter in recycled and reservoir water, respectively. New knowledge from the project will allow these water utilities to utilise the extrao ....Nanobubbles for effective and energy efficient water treatment. This project aims to produce new knowledge for developing ozone nanobubbles as a technological option for the water industry where commercially suitable technologies are unavailable. Australian water utilities have identified two key challenges: destruction of micropollutants and natural organic matter in recycled and reservoir water, respectively. New knowledge from the project will allow these water utilities to utilise the extraordinary properties of nanobubbles and the strong oxidation capability of ozone for effective and energy efficient water treatment. Tech-transfer to the industry is guaranteed through a scientifically designed pilot plant for benchmarking against the current state of the art ozonation process and reverse osmosis.Read moreRead less
Early stress experiences and stress resilience in pigs. Animal stress has substantial implications on animal productivity, health and welfare of farm animals and thus farm profitability. This project aims to examine the stress resilience in pigs. Modern pig farming is a major source of food, providing substantial nutritional, social and economic benefits in Australia and worldwide. Animal welfare is of increasing concern to the public, consumers and pork producers, and stress vulnerability is an ....Early stress experiences and stress resilience in pigs. Animal stress has substantial implications on animal productivity, health and welfare of farm animals and thus farm profitability. This project aims to examine the stress resilience in pigs. Modern pig farming is a major source of food, providing substantial nutritional, social and economic benefits in Australia and worldwide. Animal welfare is of increasing concern to the public, consumers and pork producers, and stress vulnerability is an animal health and production problem in the life of the commercial pig. This project will generate new knowledge on early life management to endow stress resilience in pigs, with expected benefits for animal welfare, farm productivity and profitability.Read moreRead less
Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade ....Sustainable Hydrogen Production from Used Water. The project aims to address the pressing challenge of water scarcity in hydrogen production by developing an innovative approach of using used water as the feed for water electrolysis. The project will result in an in-depth understanding of the impacts of water impurities in used water on the performance and durability of water electrolysers, and develop guidelines for the design of highly durable water electrolysers and the operation and upgrade of existing wastewater treatment plants. The project will advance the practical applications of water electrolysis for scalable and sustainable hydrogen production and help Australia secure a leading position in the global emerging hydrogen economy.Read moreRead less
Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, ....Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, unprecedented in scope and resolution. Outcomes include an open access database to quantify and visualise intra-urban air pollution and human exposure and develop air quality maps and smoke pollution management tools. It is expected to advance the evidence-based management of air as a resource, increasing economic prosperity and enhancing human health and quality of life.Read moreRead less
Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian po ....Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian population. Accurate and objective per-capita based consumption and release estimates for a wide range of chemicals is intended to provide a baseline against which to measure changes in our chemosphere.Read moreRead less
Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative ....Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative that could be incorporated into DTA programs if their ecological relevance can be demonstrated. This project will develop and validate a new and internationally significant suite of in vitro bioassays for incorporation into DTA programs, leading to more ethical, cost effective and improved environmental protection.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100155
Funder
Australian Research Council
Funding Amount
$648,000.00
Summary
NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an i ....NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an integrated software and hardware system called NanoMin which incorporates a spectral deconvolution engine combined with a mineral spectra database. A key limitation in understanding complex materials is sub-micron to nanometer scale spatial variability of mineralogical phases. Imaging and quantifying these phases is now possible with the NanoMin system. This promises to open up petrological, geobiological, and materials science research in complex fine-grained materials.Read moreRead less
Unravelling how aquatic coastal networks regulate nitrogen removal . The aim of this project is to determine the nitrogen removal pathways of the coastal zone using a number of innovative field and modelling approaches. Little is known about how the complex coastal landscape controls trade-offs that maximise nitrogen removal but minimise nitrous oxide (a potent greenhouse gas) emissions. The outcomes of this study will significantly advance our understanding of the coastal zone in regional and g ....Unravelling how aquatic coastal networks regulate nitrogen removal . The aim of this project is to determine the nitrogen removal pathways of the coastal zone using a number of innovative field and modelling approaches. Little is known about how the complex coastal landscape controls trade-offs that maximise nitrogen removal but minimise nitrous oxide (a potent greenhouse gas) emissions. The outcomes of this study will significantly advance our understanding of the coastal zone in regional and global nitrogen budgets. This will provide significant benefits such as a new science-based quantitative framework to facilitate best practice management to reduce terrestrial nitrogen loads and associated downstream impacts such as eutrophication, and reduce nitrous oxide emissions and associated global warming.
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Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less