Defining domains within Mycoplasma hyopneumoniae surface proteins that interact with host extracellular matrix: efficacy testing of candidate vaccines in swine. Over 90% of Australian commercial pig production facilities are affected by Mycoplasma hyopneumoniae, the causative agent of swine enzootic pneumonia. This disease causes economic losses in Australia of over $20 million per annum and up to $1 billion per annum in major swine rearing countries worldwide. This project will determine the p ....Defining domains within Mycoplasma hyopneumoniae surface proteins that interact with host extracellular matrix: efficacy testing of candidate vaccines in swine. Over 90% of Australian commercial pig production facilities are affected by Mycoplasma hyopneumoniae, the causative agent of swine enzootic pneumonia. This disease causes economic losses in Australia of over $20 million per annum and up to $1 billion per annum in major swine rearing countries worldwide. This project will determine the protective efficacy of new generation vaccines against M. hyopneumoniae, which aim to block the colonisation process and prevent disease .Read moreRead less
Phytoremediation of arsenic contaminated sites using arsenic hyperaccumulating plants. The legacy of using arsenical compounds in pest control activities has resulted in many contaminated sites. Since the inorganic arsenic is carcinogenic, stringent laws have been enforced to control arsenic (As) in the environment. This project investigates the potential of using the recently discovered (Ma et al, 2001) arsenic hyperaccumulating (22,000 mgAs/kgDW) fern, Pteris vittata, in the removal of arsen ....Phytoremediation of arsenic contaminated sites using arsenic hyperaccumulating plants. The legacy of using arsenical compounds in pest control activities has resulted in many contaminated sites. Since the inorganic arsenic is carcinogenic, stringent laws have been enforced to control arsenic (As) in the environment. This project investigates the potential of using the recently discovered (Ma et al, 2001) arsenic hyperaccumulating (22,000 mgAs/kgDW) fern, Pteris vittata, in the removal of arsenic from dip sites and railway tracks in Qld, and orchards in northern NSW. The impacts of growing hyperaccumulating plants on grazing animals and the environment, and the disposal of arsenic from contaminated plants will also be studied.Read moreRead less
Diseases caused by the pneumococcus represent the largest cause of vaccine preventable death in the world today, mainly pneumonia and meningitis. In 2011, 16 developing countries will introduce pneumococcal conjugate vaccines, none in east Asia. Lack of research has been a major barrier to their use in the region. We have established an international centre of excellence in the field and we seek support to extend the capacity of this group and to transfer the technology to Vietnam.
Assessing animal exposure to urticating caterpillar hairs and developing management strategies to reduce the consequence of foetal abortion in mares. Equine Amnionitis and Foetal Loss (EAFL) accounts for about a third of mares aborting in thoroughbred horse studs in southern Queensland, New South Wales and Victoria. Previous studies have shown that processionary caterpillars and their irritating setae (hairs) can cause EAFL. This project aims to determine the likelihood that other caterpillar sp ....Assessing animal exposure to urticating caterpillar hairs and developing management strategies to reduce the consequence of foetal abortion in mares. Equine Amnionitis and Foetal Loss (EAFL) accounts for about a third of mares aborting in thoroughbred horse studs in southern Queensland, New South Wales and Victoria. Previous studies have shown that processionary caterpillars and their irritating setae (hairs) can cause EAFL. This project aims to determine the likelihood that other caterpillar species are involved based on hair morphology and a surrogate model system. A full risk assessment of the exposure of mares to these hairs in situ will be undertaken, based on the ecology and biology of the species. Outcomes include a management strategy for EAFL-causing insects and a reduction of EAFL within the industry.Read moreRead less