Determinants Of Musculoskeletal And Other Diseases, Health Service Utilisation And Mortality In A Cohort Of Older Women
Funder
National Health and Medical Research Council
Funding Amount
$869,724.00
Summary
This longitudinal study aims to identify determinants of musculoskeletal and cardiovascular diseases, cognitive decline, mortality and health service utilisation with ageing in a cohort of well-characterised older women, whose health has been monitored since 1998. This study is unique in that it will have followed patients from mean age 75 to 90 years with longitudinal clinical data collected and complete ascertainment of health service utilisation through the WA Data Linkage System.
Osteoblast Control Of Mesenchymal Progenitor Cell Differentiation: The Role Of Glucocorticoids And Wnt Signalling.
Funder
National Health and Medical Research Council
Funding Amount
$443,131.00
Summary
Osteoporosis is an important and growing health issue. Reduced ability to make new bone is an important cause of osteoporosis. In this project we will study how the immature cells which eventually make bone are recruited and controlled. In particular, we will study how genes coding for important growth factors are regulated so that the proper signals are sent to young cells to induce them to become bone-making rather than fat-making cells.