Discovery Early Career Researcher Award - Grant ID: DE200101832
Funder
Australian Research Council
Funding Amount
$425,941.00
Summary
Mechanisms of immune protection for infectious laryngotracheitis virus. This project aims to investigate the mechanisms of immune protection against infectious laryngotracheitis virus. This will be achieved by investigating the role of local and systemic immunity and the immune cells associated with long-term protection against disease. The mechanisms of protection against this virus remain unknown which impairs the development of efficacious vaccines. Expected outcomes of this project are a mor ....Mechanisms of immune protection for infectious laryngotracheitis virus. This project aims to investigate the mechanisms of immune protection against infectious laryngotracheitis virus. This will be achieved by investigating the role of local and systemic immunity and the immune cells associated with long-term protection against disease. The mechanisms of protection against this virus remain unknown which impairs the development of efficacious vaccines. Expected outcomes of this project are a more rational approach to vaccination resulting in the generation of more effective and safer vaccination strategies that should benefit our important poultry industry. Additionally, the new methodologies and knowledge on mucosal immune markers could be utilised for the study of other pathogens.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101470
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shap ....Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shapes the gut microbiota for life and has the strongest influence on development of the immune system. Accordingly, at-hatch administration of proven beneficial strains to poultry is likely to ensure permanent colonisation with beneficial bacteria. This process would improve both the productivity and health of poultry and other agricultural animals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101503
Funder
Australian Research Council
Funding Amount
$357,996.00
Summary
Using improved markets to reduce over-extraction of groundwater. This project aims to investigate the key aspects needed for a successful groundwater market, including extraction limits, innovative trading systems and reasonable transaction costs. The outcomes of the project can contribute to environmental benefits that minimise short-term financial losses to irrigators. The project also expects to enhance the capacity of water agencies to implement cap and trade systems that can reduce over-ext ....Using improved markets to reduce over-extraction of groundwater. This project aims to investigate the key aspects needed for a successful groundwater market, including extraction limits, innovative trading systems and reasonable transaction costs. The outcomes of the project can contribute to environmental benefits that minimise short-term financial losses to irrigators. The project also expects to enhance the capacity of water agencies to implement cap and trade systems that can reduce over-extraction.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100922
Funder
Australian Research Council
Funding Amount
$408,490.00
Summary
Foresight: Anticipatory decision-making in water resource management. Long-term planning is vital to secure Australia’s water resources in the face of environmental disruption. This project aims to contribute to sustainable and equitable water management by examining the efficacy of anticipatory decision-making approaches. Qualitative research will be used to examine how scientific knowledge is used or contested in water reform within the Murray-Darling Basin. Intended outcomes include improved ....Foresight: Anticipatory decision-making in water resource management. Long-term planning is vital to secure Australia’s water resources in the face of environmental disruption. This project aims to contribute to sustainable and equitable water management by examining the efficacy of anticipatory decision-making approaches. Qualitative research will be used to examine how scientific knowledge is used or contested in water reform within the Murray-Darling Basin. Intended outcomes include improved capacities to plan for future change and establishing anticipatory decision-making within Australian natural resource management. This should provide significant benefits based on an integrated approach to science and decision-making that addresses trade-offs between stakeholders to identify shared action pathways.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100158
Funder
Australian Research Council
Funding Amount
$405,751.00
Summary
Addressing vaccine rejection: drivers and impact of mandatory vaccination. This project aims to investigate and analyse the introduction, design and implementation of mandatory child vaccination programs in Italy, France, Australia and California, using a comparative case study approach. Parental rejection of childhood vaccines can cause illness and death. However, governments limiting personal liberty can erode public acceptance. The project’s goal is to provide the tools, framework and concept ....Addressing vaccine rejection: drivers and impact of mandatory vaccination. This project aims to investigate and analyse the introduction, design and implementation of mandatory child vaccination programs in Italy, France, Australia and California, using a comparative case study approach. Parental rejection of childhood vaccines can cause illness and death. However, governments limiting personal liberty can erode public acceptance. The project’s goal is to provide the tools, framework and conceptual clarity to help researchers and policymakers consider the merits and limitations of strategies which mandate childhood vaccination.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101216
Funder
Australian Research Council
Funding Amount
$356,291.00
Summary
Revitalising Collaborative Water Governance: Lessons from Water Planning in Australia. One of Australia's greatest challenges is managing its scarce water resources. However, fundamental flaws in the design and implementation of collaborative water governance have undermined Australia's water reforms. This project will critically evaluate collaborative water governance, develop legal and policy principles enabling its mobilisation in an effective, efficient and equitable manner, and investigate ....Revitalising Collaborative Water Governance: Lessons from Water Planning in Australia. One of Australia's greatest challenges is managing its scarce water resources. However, fundamental flaws in the design and implementation of collaborative water governance have undermined Australia's water reforms. This project will critically evaluate collaborative water governance, develop legal and policy principles enabling its mobilisation in an effective, efficient and equitable manner, and investigate the challenges it poses for the theory and practice of water regulation, markets and water governance more generally. The lessons learned can then be applied to reshape water strategy, ensure meaningful collaborative community engagement and reduce the over-allocation and overuse of water in Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100735
Funder
Australian Research Council
Funding Amount
$395,204.00
Summary
Understanding infectious laryngotracheitis virus recombination. This project will study the factors that lead to recombination between strains of infectious laryngotracheitis virus (ILTV) concomitant with increased virulence. In previous studies of ILTV, two new genotypes of virulent field strains were shown to be independent recombinants derived from distinct attenuated ILTV commercial vaccines. These strains became the dominant field viruses responsible for widespread and severe disease outbre ....Understanding infectious laryngotracheitis virus recombination. This project will study the factors that lead to recombination between strains of infectious laryngotracheitis virus (ILTV) concomitant with increased virulence. In previous studies of ILTV, two new genotypes of virulent field strains were shown to be independent recombinants derived from distinct attenuated ILTV commercial vaccines. These strains became the dominant field viruses responsible for widespread and severe disease outbreaks in Australian poultry flocks. This project will enhance understanding of the conditions that led to these deleterious natural recombination events and enable the industry to avoid the emergence of new virulent field strains in the future. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100922
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
An international environmental history of the 'world ocean', 1950s-2000s. This project aims to investigate the ways in which states, international organisations, and international communities have engaged with the ‘world ocean’ as a natural environment from the 1950s to the 2000s. In the context of current environmental and geopolitical challenges for the ocean, this project will analyse how these actors built institutions, communities, and territories in and for the ocean environment as a found ....An international environmental history of the 'world ocean', 1950s-2000s. This project aims to investigate the ways in which states, international organisations, and international communities have engaged with the ‘world ocean’ as a natural environment from the 1950s to the 2000s. In the context of current environmental and geopolitical challenges for the ocean, this project will analyse how these actors built institutions, communities, and territories in and for the ocean environment as a foundation for generating knowledge and claiming power, rights, and resources. By understanding the structures and origins of contemporary ocean ideas, spaces, and institutions, this project aims to benefit current efforts to create resilient ocean environments and communities at the international scale.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100440
Funder
Australian Research Council
Funding Amount
$419,693.00
Summary
A novel approach in crowd evacuation planning: Behavioural intervention. The ability to rapidly and safely evacuate crowds can mean the difference between death and survival in mass emergencies. While the immediate reaction of the public to an emergency is paramount for their survival, their role in crisis management is often not fully harnessed. This project establishes an innovative and pragmatic approach in urban emergency planning: optimising evacuations through behavioural training. Pioneer ....A novel approach in crowd evacuation planning: Behavioural intervention. The ability to rapidly and safely evacuate crowds can mean the difference between death and survival in mass emergencies. While the immediate reaction of the public to an emergency is paramount for their survival, their role in crisis management is often not fully harnessed. This project establishes an innovative and pragmatic approach in urban emergency planning: optimising evacuations through behavioural training. Pioneering empirical steps will be taken to discover optimum strategies that individual crowd members should adopt, and to establish the extent to which modifying crowd response can be effective. The outcomes will result in educational guides that will increase public awareness and community preparedness for public emergencies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100295
Funder
Australian Research Council
Funding Amount
$455,563.00
Summary
Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the earl ....Unlocking the helminth ‘early infection gap’ using 3D cell culture models. This project aims to revolutionise the study of critical early host-parasite interactions using innovative 3D cell culture models, reducing our dependence on animal infections. Liver fluke is the most economically important zoonotic parasite of Australian livestock and is a significant contributor to global food insecurity. Due to the reliance of parasites on mammalian hosts to survive, very little is known about the early infection process. Expected outcomes include new knowledge on key migratory stimuli and liver fluke biology. Benefits include the identification of drug targets and vaccine candidates for use in livestock via the development of animal-free in vitro screening platforms that will serve as a prototype for other parasites.Read moreRead less