The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The curr ....The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The current project is directly relevant to the genetics of mental disorders, such as attention deficit hyperactivity (ADHD), that place a large burden, both financially and emotionally, on our society. Understanding the genes and biological pathways that increase risk for mental disorders will ultimately lead to improved treatments for these conditions.Read moreRead less
Improving the quality of life of children born very premature. This research program is in line with the national research priority to promote good health and well being, and more specifically to provide a healthy start to life for high-risk infants. This research program is attempting to improve the quality of life of infants born very preterm by improving our understanding of the nature of the problems faced by these high-risk children. This knowledge will inform future preventative care and ....Improving the quality of life of children born very premature. This research program is in line with the national research priority to promote good health and well being, and more specifically to provide a healthy start to life for high-risk infants. This research program is attempting to improve the quality of life of infants born very preterm by improving our understanding of the nature of the problems faced by these high-risk children. This knowledge will inform future preventative care and early intervention strategies. More directly, this research program incorporates a series of randomised controlled trials which are all attempting to improve the health and well being of these vulnerable infants.Read moreRead less
Cognitive, behavioural and educational outcomes of fetal antiepileptic drug exposure. The study falls within the National Research Priority of Promoting and Maintaining Good Health, in particular the Priority Goal - A Healthy Start to Life. The research will yield information crucial to our understanding of the effects of fetal AED exposure on cognitive and behavioural development in the significant number of affected Australian children born each year. It will enhance the nation's ability to de ....Cognitive, behavioural and educational outcomes of fetal antiepileptic drug exposure. The study falls within the National Research Priority of Promoting and Maintaining Good Health, in particular the Priority Goal - A Healthy Start to Life. The research will yield information crucial to our understanding of the effects of fetal AED exposure on cognitive and behavioural development in the significant number of affected Australian children born each year. It will enhance the nation's ability to develop strategies for prevention, surveillance and remediation of adverse outcomes in early childhood, thus supporting the Government's National Agenda for Early Childhood initiative. As a consequence educational assistance can be targeted for those children likely to experience difficulties. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0239381
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
Sleep-wake problems in people without primary sleep disorders. Portable sleep recording equipment will enable research to be conducted on sleep wake issues in people under a variety of conditions; such as those arising from substance intake (alcohol, nicotine, caffeine), life stage (menopause, elderly), developmental disorders (intellectual disability, autism, fragile X, ADHD) and other syndromes (chronic pain, depression). This is of particular significance given that sleep problems can cause ....Sleep-wake problems in people without primary sleep disorders. Portable sleep recording equipment will enable research to be conducted on sleep wake issues in people under a variety of conditions; such as those arising from substance intake (alcohol, nicotine, caffeine), life stage (menopause, elderly), developmental disorders (intellectual disability, autism, fragile X, ADHD) and other syndromes (chronic pain, depression). This is of particular significance given that sleep problems can cause daytime sleepiness, fatigue, poor vigilance, lack of attention, negative mood and poor memory. The establishment of this cross-institutional collaborative facility will permit ongoing scientific investigation of such sleep-wake issues with beneficial health and safety implications for community.Read moreRead less
Elucidating the neurobiological basis for developmental stuttering using modern brain imaging techniques. We plan to untilise brain imaging techniques to examine the neurological underpinnings of stuttering. We aim to develop new tools for functional magnetic resonance imaging (fMRI) to examine the patterns of brain activation in the motor, speech and language areas, specifically for use in children who stutter. We aim to answer the question of whether stuttering is a motor-speech or a language ....Elucidating the neurobiological basis for developmental stuttering using modern brain imaging techniques. We plan to untilise brain imaging techniques to examine the neurological underpinnings of stuttering. We aim to develop new tools for functional magnetic resonance imaging (fMRI) to examine the patterns of brain activation in the motor, speech and language areas, specifically for use in children who stutter. We aim to answer the question of whether stuttering is a motor-speech or a language disorder and to establish whether variations in the speech and language regions of the brain found in adult stuttering research are also present in children who stutter, and to explore the possibility that different variations in brain activation and/or morphology may predict persistence and recovery.
Read moreRead less