Radio-magnetic nanoparticles as bimodal positron emission tomography/magnetic resonance imaging contrast agents for dendritic cell tracking. Biomedical imaging is limited by a lack of commercial dual-mode contrast agents, which may be simultaneously used for magnetic resonance (MR) and positron emission tomography (PET) imaging. This project will develop a nanotechnology-based biocompatible dual-mode contrast agent for simultaneous PET and MR imaging, reducing associated side effects.
A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interaction ....A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interactions. This project will address this very important issue by evaluating a range of surface functionalised nanoparticles in highly significant models of medical emergencies. This project will enable development of advanced therapeutic interventions for cancer, central nervous system injuries, cardiovascular diseases and pregnancy related disorders.Read moreRead less
Optimisation of functional mesoporous materials for low-abundance biomarkers quantification towards biodiagnostic applications. Using state-of-the-art nanotechnology, a novel approach will be developed to quantitatively analyse low abundance peptides and proteins. This will aid in the detection of a biomarker in osteoarthritis, a disease affecting 3.85 million Australians. This project has significance for the early diagnosis and improved treatment of this disease.
Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e ....Organically-Capped Copper Nanowires for Soft Electronic Skin Sensors. Soft skin-like electronics can enable applications that are impossible to achieve with today's rigid circuit board technologies. However, it is difficult to realise such future soft electronics with traditional materials and conventional manufacturing methodologies. This project aims to synthesise novel organically-capped copper nanowires as electronic inks (e-inks) for developing cost-effective, soft, stretchable conductor (e-skin) sensors, which are wearable for monitoring blood pulses, body motions and hand gestures in real-time and in situ. This is expected to advance our knowledge in nanotechnology and generate patentable technologies in soft e-skin sensors, and to bring significant scientific and economic gains to Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100488
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Cellular dynamics of nanoengineered particles. Nanotechnology has the capacity to drive a new wave of biological innovation through engineering materials at the nanoscale. This project will advance understanding of how nanoengineered materials interact with biological systems to enable the development of nanomaterials for future translational research.
Soft Plasmene Nanosheets for Stretchable Plasmonic Skins. Conventional plasmonic sensors and devices are rigid, planar, and not stretchable. This project aims to apply plasmene materials developed at Monash's Nanobionics lab to design highly stretchable plasmonic devices (artificial plasmonic skins). Systematic experimental and theoretical studies will be undertaken to understand how the plasmonic skins respond to strains and how they can be used for fabricating novel stretchable devices. Such s ....Soft Plasmene Nanosheets for Stretchable Plasmonic Skins. Conventional plasmonic sensors and devices are rigid, planar, and not stretchable. This project aims to apply plasmene materials developed at Monash's Nanobionics lab to design highly stretchable plasmonic devices (artificial plasmonic skins). Systematic experimental and theoretical studies will be undertaken to understand how the plasmonic skins respond to strains and how they can be used for fabricating novel stretchable devices. Such studies will generate important new knowledge of fabrication, characterisation, and modelling of stretchable plasmene, hence, contributing to further Australian standing in the field of nanotechnology and plasmonics. It may also incubate patentable technologies, bringing potential economic gains.Read moreRead less
Development of next-generation nanoengineered advanced materials for targeted applications. This proposal seeks to develop and use a novel next-generation nanoscale fabrication technique to assemble technologically advanced materials not accessible via current fabrication strategies. The resulting materials are expected to find application in water purification, pharmaceutical development and drug delivery.
Ultrastretchable, Highly Transparent, Wearable Gold Nanowire Generators. Next-generation wearable electronics should be thin, soft and even transparent, enabling applications impossible to achieve with traditional rigid electronics. Such future electronics will require disruptive soft skin-conformal energy devices to power. This project aims to develop a bi-modal gold nanowire percolation strategy to design ultrathin conductors that are electrically conductive, optically transparent and mechanic ....Ultrastretchable, Highly Transparent, Wearable Gold Nanowire Generators. Next-generation wearable electronics should be thin, soft and even transparent, enabling applications impossible to achieve with traditional rigid electronics. Such future electronics will require disruptive soft skin-conformal energy devices to power. This project aims to develop a bi-modal gold nanowire percolation strategy to design ultrathin conductors that are electrically conductive, optically transparent and mechanically stretchable. It expects to generate new knowledge in nanomaterials design and new technologies to fabricate skin-like invisible wearable generators. This should provide significant benefits in advancing Australian standing in the fields of nanotechnology and energy science, and bringing potential economic gains.Read moreRead less
Highly durable electronic skins for multifunctional tactile sensing. This project aims to develop next-generation, multifunctional, wearable tactile sensors that can perceive and discriminate between different types of physical and chemical stimuli. These wearable e-skin sensors will mimic the sensing capabilities of real skin, and will measure a broader range of aspects of a person’s physical and biological condition than current wearable sensors. It will generate a new platform technology capa ....Highly durable electronic skins for multifunctional tactile sensing. This project aims to develop next-generation, multifunctional, wearable tactile sensors that can perceive and discriminate between different types of physical and chemical stimuli. These wearable e-skin sensors will mimic the sensing capabilities of real skin, and will measure a broader range of aspects of a person’s physical and biological condition than current wearable sensors. It will generate a new platform technology capable of commercialisation, bringing economic gains to Australia.Read moreRead less