Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100088
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
nano infrared and sub micron Raman spectroscopy and imaging. Nano infrared and sub micron raman spectroscopy and imaging: Near-field Infrared (IR) spectroscopy and imaging systems will be coupled to near-field scanning optical microscopes to provide IR spectroscopy and molecular images at less than 20 nanometre lateral resolution. This is unprecedented resolution for infrared fingerprinting and molecular imaging. For two months a year the spectroscopy system will be coupled to the IR beamline at ....nano infrared and sub micron Raman spectroscopy and imaging. Nano infrared and sub micron raman spectroscopy and imaging: Near-field Infrared (IR) spectroscopy and imaging systems will be coupled to near-field scanning optical microscopes to provide IR spectroscopy and molecular images at less than 20 nanometre lateral resolution. This is unprecedented resolution for infrared fingerprinting and molecular imaging. For two months a year the spectroscopy system will be coupled to the IR beamline at the Australian synchrotron, to provide full IR spectral coverage available to all Australian and New Zealand scientists. A confocal raman spectrometer will be upgraded to the ultraviolet to provide spectra at less than 150 nanometre resolution. These systems will provide a unique Australian resource for nanoscientists, biomedical researchers and materials scientists requiring molecular information on the nanoscale.Read moreRead less
Design and Fabrication of Molecular Machines: the Nanomachines of the Future. Nanotechnology that incorporates the use of nanomachines and molecular machines is an exciting new area of translational research, with broad potential in biomedical technology and industrial applications. We are developing new molecular machines and optimising their assembly. Recent innovation in the world of nanotechnology concerns the design and manufacture of synthetic and hybrid machines, based on existing biologi ....Design and Fabrication of Molecular Machines: the Nanomachines of the Future. Nanotechnology that incorporates the use of nanomachines and molecular machines is an exciting new area of translational research, with broad potential in biomedical technology and industrial applications. We are developing new molecular machines and optimising their assembly. Recent innovation in the world of nanotechnology concerns the design and manufacture of synthetic and hybrid machines, based on existing biological molecular machines but incorporating synthetic parts. Australia has an opportunity to be at the forefront of these new developments in nanotechnology, with a new generation of Australian scientists being trained across the foundation disciplines of chemistry, physics and molecular biology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE150101518
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Cellular responses to nanoparticles from cells on micropatterned surfaces. The mechanisms underlying cell-nanoparticle interactions remain largely unknown. It has hampered the design and development of innovative nano devices to be used for drug delivery, biomarkers and diagnostics. This project aims to explore the influences of cell size, density, geometry, intercellular communication and substrate properties on cell-nanoparticle interactions. A micropatterning technology is applied to precisel ....Cellular responses to nanoparticles from cells on micropatterned surfaces. The mechanisms underlying cell-nanoparticle interactions remain largely unknown. It has hampered the design and development of innovative nano devices to be used for drug delivery, biomarkers and diagnostics. This project aims to explore the influences of cell size, density, geometry, intercellular communication and substrate properties on cell-nanoparticle interactions. A micropatterning technology is applied to precisely control cell behaviour and provide a novel in vitro cellular model for nanoparticle studies. This project aims to significantly improve the understanding of cell-nanoparticle interactions to provide new insight into nanoparticle design and improve the efficacy of nano devices.Read moreRead less
High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magn ....High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magnetic fields and carbon nanostructure formation. Expected outcomes for this project include exquisite control on reforming nanocarbon with tuneable properties and unprecedented hetero-structures. This should provide significant benefits, such as in generating new processes and products for advanced manufacturing. Read moreRead less
Processing Pearl Nacre for Bio-Nanotechnology. Nanotechnology has exciting potential to solve major health challenges of the 21st century. The proposed research focuses on developing health care products, derived from a renewable waste stream resource from the pearling industry, en route to establishing products to benefit the rural community, and beyond. The processed pearl nacre provides the possibility of alleviating problems associated with neurotrauma following injury, and for skin regenera ....Processing Pearl Nacre for Bio-Nanotechnology. Nanotechnology has exciting potential to solve major health challenges of the 21st century. The proposed research focuses on developing health care products, derived from a renewable waste stream resource from the pearling industry, en route to establishing products to benefit the rural community, and beyond. The processed pearl nacre provides the possibility of alleviating problems associated with neurotrauma following injury, and for skin regeneration following burns. The recently established powerful multidisciplinary research team in partnership with Pearl Technology combines expertise in chemical processing, nanotechnology, biochemistry, neuroscience and tissue engineering, also providing a basis for quality research training.Read moreRead less
Application of microfluidics in engineering functional noble metal nano-materials. High value added nano-materials based on precious metals from gold refining will be developed using continuous flow microfluidic platforms in parallel, in partnership with the Perth Mint (WA Mint). The scalable products will be assessed for application in devices and sensor technology, and as a catalysis for the fine chemical industry.
Controlling nano-carbon complexity and function. The project aims to develop versatile continuous flow thin film microfluidic device technology incorporating different external fields, including innovative magnetic or electric fields coupled with pulsed lasers, for gaining access to novel nano-carbon material for which current methods are ineffective or of limited utility. The technology will allow exquisite control, with real time monitoring, on reforming of carbon into functional material with ....Controlling nano-carbon complexity and function. The project aims to develop versatile continuous flow thin film microfluidic device technology incorporating different external fields, including innovative magnetic or electric fields coupled with pulsed lasers, for gaining access to novel nano-carbon material for which current methods are ineffective or of limited utility. The technology will allow exquisite control, with real time monitoring, on reforming of carbon into functional material with tunable properties, along with the self assembly of nano-carbon, and fabricating composites of nano-carbon material. Understanding their fundamental properties including photoluminescence will be targeted, for leveraging the properties in applications to generate new processes and products.
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Structural diverse nanocarbon using continuous flow thin film microfluidics. This project aims to develop continuous flow thin film microfluidic device technology to gain access to nano-carbon material or carbon nano-material. This project will exploit high shear stress in dynamic thin films, field effects, including Faraday waves, plasma, magnetic, laser and LED irradiation. The technology is expected to allow both scalable ‘top down’ synthesis of graphene scrolls, laterally slicing carbon nano ....Structural diverse nanocarbon using continuous flow thin film microfluidics. This project aims to develop continuous flow thin film microfluidic device technology to gain access to nano-carbon material or carbon nano-material. This project will exploit high shear stress in dynamic thin films, field effects, including Faraday waves, plasma, magnetic, laser and LED irradiation. The technology is expected to allow both scalable ‘top down’ synthesis of graphene scrolls, laterally slicing carbon nanotubes and composites of different types of carbon, and ‘bottom up’ synthesis of nano-carbon from natural saccharides. By incorporating sustainability metrics including scalability, renewable feed-stocks and minimising waste, this research is expected to be attractive to industry and minimise the effect on the environment.Read moreRead less
The Protein Corona: Imaging the nanoparticle biological identity card. The project will determine how the intrinsic physico-chemical properties of nanoparticles translate into extrinsic biological properties through their interaction with physiological proteins in the body. This process is complex and poorly understood due to our inability to visualise it through standard imaging techniques. The project aims to develop a new tool to visualise, study, quantify and design the protein ‘corona’. The ....The Protein Corona: Imaging the nanoparticle biological identity card. The project will determine how the intrinsic physico-chemical properties of nanoparticles translate into extrinsic biological properties through their interaction with physiological proteins in the body. This process is complex and poorly understood due to our inability to visualise it through standard imaging techniques. The project aims to develop a new tool to visualise, study, quantify and design the protein ‘corona’. These are the adsorbed protein layers that are rapidly formed in contact with biological liquids which allow cells to recognise and process nanoparticles. The proteins are dependent on factors such as size, shape, surface chemistry and biological history of the particles. Being able to ‘read’ and ‘write’ the protein corona would enable efficient cellular targeting of pharmaceutical drugs.Read moreRead less
Nanoparticle inks for electronic applications employing nanostructured thin-films. The development of next-generation technologies requires careful engineering of materials at the nanoscale. Using nanoparticle inks, many of the engineering difficulties which exist at these length scales can be overcome, thus allowing for technologies such as thin-film solar cells to become cheaper and more efficient.