Improved Patient Outcomes By Early Intervention With Therapeutic Cooling For Patients With Severe Traumatic Brain Injury, And By Optimising Patient Blood Transfusion Practice In Critically Ill Patients.
Funder
National Health and Medical Research Council
Funding Amount
$380,450.00
Summary
First, a large multicentre trial (POLAR) will complement my previous successful trials in traumatic brain injury (TBI) patients and will establish whether active therapeutic cooling, commenced early after brain injury and continued in intensive care units, will achieve its promise of improving patient outcomes. Second, a national multicentre trial (TRANSFUSE) will establish whether transfusing blood units with a shorter than usual storage time will improve patient outcomes.
Generating And Applying Clinical Research To Improve The Outcomes Of Neonatal Intensive Care
Funder
National Health and Medical Research Council
Funding Amount
$568,892.00
Summary
Birth is a complex process and sometimes babies require help to make the transition to independent life. Professor Peter Davis is conducting research into how best to support this transition. This involves helping the lungs to work efficiently and supporting the changes in circulation of the blood to the brain and to the rest of the body. His work aims to quickly identify babies who need help and then provide better treatments to make sure they have the best chance of a healthy life.
Researching Functioning, Disability And Rehabilitation: Translation Into Policy And Practice
Funder
National Health and Medical Research Council
Funding Amount
$481,167.00
Summary
Appropriate support, including responsive health services, is a key to assisting people with disabilities. Disability is most common in older age but acquired disability, particularly following injury, is important in younger people. This research proposal investigates functioning, disability and rehabilitation across the adult lifespan and aims to translate research findings into policy and practice.
Improving Clinical Understanding And Management Of Tendinopathy
Funder
National Health and Medical Research Council
Funding Amount
$487,621.00
Summary
Painful tendons occur in people of all ages. Treatment outcomes are variable and many people are left with chronic pain and limited capacity to be active. This research will investigate the development of tendinopathy, the cause of tendon pain and examine imaging methods to improve management. This research expects to demonstrate that tendon injury develops during puberty, that the brain has a central role in tendon pain, and that regular monitoring of tendon structure can improve outcomes.
I am a practising hospital physician and a trained scientist and am widely acknowledged at the world leader in my field of study, asbestos cancers. Our latest research discoveries have put us on the threshold of bold new approaches to curing the scourge of these cancers and finding better blood tests but this work now requires extra attention from me to bring it to fruition. A Practitioner Fellowship is an ideal way for me to continue to lead this exciting research.
Mild traumatic brain injury (TBI) is a leading cause of death and disability in Australia, especially in young populations. Although many patients recover uneventfully following mild TBI, complications such as prolonged symptoms, depression and cognitive deterioration may occur. With considerable advancements in neuroimaging and cognitive assessment in recent years, newer techniques may provide a window to directly observe changes that accompany mild TBI.
Mild Traumatic Brain Injury And The Risk Of Long-term Neurodegenerative And Neurobehavioural Disease
Funder
National Health and Medical Research Council
Funding Amount
$585,269.00
Summary
Considerable media attention surrounds the potential for long-term problems in individuals with high exposure to head impacts such as seen in sporting, civilian and/or military contexts. This study examines the long-term effects of mild traumatic brain injury (mTBI) and helps close the current knowledge gap of the impact of this disorder on individuals. There are no long term trials to answer the critical question of whether mild TBI causes long term problems in the brain.
This application will allow me to restructure my work to provide sufficient time to do full justice to the current and planned commitments of our Respiratory Research Group. Our research programme includes the immunopathology of chronic airway diseases; the epidemiology of respiratory disease (TAHS); clinical physiology technology to service these studies; respiratory clinical pharmacology; microbe-host interactions in CF and COPD; and EBM in chronic respiratory disease self-management .
Stephen Stick Practitioner Fellowship In Paediatric Respiratory Medicine
Funder
National Health and Medical Research Council
Funding Amount
$542,272.00
Summary
Fellowship will facilitate the further study of mechanisms of chronic childhood respiratory disease and strategies for intervention to reduce morbidity and improve quality of life for patients and families.
An Integrated Research Program In Clincial Toxicology Toxicovigilance And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$568,892.00
Summary
Drug-related deaths in Australia account for 6.6% of all deaths (ABS 2009). In much of the rural Asia-Pacific, pesticide poisoning and snakebite are major problems. This research supports an integrated national and international clinical toxicology research program covering medicine and chemical poisoning, serious adverse drug reactions, snake and spider bite. Its focus is on the applied research needed to detect new problems and rapidly translate early findings into better treatment, regulation ....Drug-related deaths in Australia account for 6.6% of all deaths (ABS 2009). In much of the rural Asia-Pacific, pesticide poisoning and snakebite are major problems. This research supports an integrated national and international clinical toxicology research program covering medicine and chemical poisoning, serious adverse drug reactions, snake and spider bite. Its focus is on the applied research needed to detect new problems and rapidly translate early findings into better treatment, regulations & policy.Read moreRead less