Improving Pain And Movement Outcomes In Symptomatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
People fear getting painful knee osteoarthritis (OA) more than any other disease – it is seen as progressive and incurable. It often stops people from moving and staying healthy, resulting in an enormous burden on sufferers and the health care system. This program of research aims to understand what brain & nervous system processes might underlie these pain and movement problems and whether new brain-targeting treatment helps. This will allow us to better match treatment to what patients need.
Industrial Transformation Training Centres - Grant ID: IC190100020
Funder
Australian Research Council
Funding Amount
$3,998,796.00
Summary
ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simula ....ARC Industrial Transformation Training Centre for Joint Biomechanics. The Centre aims to bring together leading researchers, industry partners and end-users to train a new generation of interdisciplinary and skilled graduates to tackle industry-focused challenges in joint biomechanics. The centre will provide advances required to transform personalised surgical treatment of joints through integrated technologies of computer tools for pre-surgical planning and decision making, the computer simulation system and robot simulators for surgical training and medical device assessment, and post-surgical assessment tools. The outcomes of the centre will significantly contribute to Australia by improved health outcomes, economic benefits, and a skilled workforce able to advance this joint biomechanics fields.Read moreRead less
Understanding and preventing gun violence: A qualitative study. Gun violence causes significant harm across Australian communities. Excluding sexual assault, firearms feature in nearly one in 10 violent crimes. The annual costs of gun violence run into tens of millions of dollars. This project aims to make an original qualitative contribution to understanding and preventing gun violence in three contexts: drug dealing/trafficking, other organised crime activity, and armed robbery. The proposed r ....Understanding and preventing gun violence: A qualitative study. Gun violence causes significant harm across Australian communities. Excluding sexual assault, firearms feature in nearly one in 10 violent crimes. The annual costs of gun violence run into tens of millions of dollars. This project aims to make an original qualitative contribution to understanding and preventing gun violence in three contexts: drug dealing/trafficking, other organised crime activity, and armed robbery. The proposed research would be the first study nationally - and one of the very few internationally - to interview convicted gun crime users about the acquisition and use of firearms in criminal life. Project results are expected to have direct implications for reducing the impact of gun violence in Australia.Read moreRead less
Identifying optimal daily levels of movement behaviours in early childhood. This project aims to discover how much physical activity, sedentary behaviour and sleep young children need each day to best support their development. Through the creation of an international database and the application of innovative analytics, the project seeks to determine the optimal daily balance of these behaviours that results in the best developmental outcomes for young children. The project is expected to infor ....Identifying optimal daily levels of movement behaviours in early childhood. This project aims to discover how much physical activity, sedentary behaviour and sleep young children need each day to best support their development. Through the creation of an international database and the application of innovative analytics, the project seeks to determine the optimal daily balance of these behaviours that results in the best developmental outcomes for young children. The project is expected to inform national movement behaviour guidelines. The expected benefit for parents and professionals is improved confidence in supporting children’s physical activity, sedentary behaviour and sleep. The expected benefit for children is positive development, given the broad impacts of these behaviours on health and well-being.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
Two-price quantitative finance. This project aims to establish a novel field, namely two-price quantitative finance, and explore its applications. The new field will integrate two major schools for modelling and explain the presence of two prices, the buying and selling prices, widely observed in the real-world markets, and the equilibrium approach from the fundamental law of one price. The outcomes would deepen our understanding of the fundamental relationship among liquidity, prices, risk and ....Two-price quantitative finance. This project aims to establish a novel field, namely two-price quantitative finance, and explore its applications. The new field will integrate two major schools for modelling and explain the presence of two prices, the buying and selling prices, widely observed in the real-world markets, and the equilibrium approach from the fundamental law of one price. The outcomes would deepen our understanding of the fundamental relationship among liquidity, prices, risk and the economy. This project expects to bring about long-term impact on quantitative finance and related applications through providing a deep understanding of, and a new perspective for, the design, risk and fairness of the finance, property and insurance markets.Read moreRead less
G-expectation and its applications to nonlinear risk management. This project will develop novel theories and methods for nonlinear risk management based on nonlinear expectations and Backward Stochastic Differential Equations. The expected outcomes of the project will place Australia in the forefront and the leading position of these fields.
Making Green Guard® greener: enhancing the efficacy of a biopesticide. The project aims to identify naturally occurring micro-organisms to increase the effectiveness of Green Guard ®, which is a biopesticide used against the Australian plague locust. The project will use next-generation sequencing and other molecular techniques to potentially identify candidate microbes or combinations of microbes that can be added to Green Guard to enhance locust susceptibility. The project also aims to quantif ....Making Green Guard® greener: enhancing the efficacy of a biopesticide. The project aims to identify naturally occurring micro-organisms to increase the effectiveness of Green Guard ®, which is a biopesticide used against the Australian plague locust. The project will use next-generation sequencing and other molecular techniques to potentially identify candidate microbes or combinations of microbes that can be added to Green Guard to enhance locust susceptibility. The project also aims to quantify the interactive impact of temperature and nutrition on immune function, disease resistance and host-plant quality of plague locusts; and to explore the combined effects of temperature, habitat and Green Guard, in combination with candidate microbes or pathogens, on the behaviour and collective movement of locusts. It is anticipated that this will have implications for management and control strategies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100041
Funder
Australian Research Council
Funding Amount
$680,320.00
Summary
National laser-based non-destructive evaluation system. This project aims to establish the first Australian national facility for non-destructive evaluation, consisting of a three-dimensional scanning laser vibrometer, laser shearography, and an optical de-rotator, to enable full-field characterisation of the deformation and damage state of materials and structures. This solution is expected to perform rapid, broad-area scans, characterise dynamic response and wave propagation in human-engineere ....National laser-based non-destructive evaluation system. This project aims to establish the first Australian national facility for non-destructive evaluation, consisting of a three-dimensional scanning laser vibrometer, laser shearography, and an optical de-rotator, to enable full-field characterisation of the deformation and damage state of materials and structures. This solution is expected to perform rapid, broad-area scans, characterise dynamic response and wave propagation in human-engineered or natural structures, and diagnose rotating systems. This will enhance experimental capabilities, with uses spanning many industry sectors including aerospace, naval, automotive and medical.Read moreRead less
Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si a ....Silicon: a novel solution to reduce water use and pest damage in wheat. The project aims to improve Australian wheat production by increasing drought resilience and reducing reliance on pesticides. This is achieved by incorporating amorphous silicon (Si), an abundant national resource. Si uptake by wheat has been proven to alleviate stress from drought and pests, but mechanisms and agronomic feasibility remain to be fully assessed. The project will deliver a mechanistic understanding of how Si alleviates stress in wheat, from gene to farm scale, providing cost-benefit analysis and a best–practice toolbox for implementation by farmers. Outcomes are anticipated to provide a cheaper and more environmentally sustainable solution to issues of water scarcity and yield losses to pests in Australia’s leading crop.Read moreRead less