Brain Repair Following Stroke: The Role Of Npas4, A Neural-specific Transcription Factor
Funder
National Health and Medical Research Council
Funding Amount
$611,053.00
Summary
Stroke is the #1 cause of adult disability in Australia and #2 cause of death. About 60,000 Australians suffer a stroke each year while about 250,000 live with the disabilities of stroke, costing over $2B/year. The Queen Elizabeth Hospital and University of Adelaide will study why the Npas4 gene switches on after stroke and the role it plays in brain repair. Future health benefits may be tests to help improve stroke outcome in patients and therapy to decrease loss of brain cells after stroke.
Intelligent Resource Allocation Techniques for Next Generation Wireless Mobile Communication Networks. The project will develop radio and network resource allocation techniques to maximise network utilisation and to offer guaranteed Quality of Service (QoS) for multimedia traffic in 3G/4G wireless mobile communication networks. In particular, this work will study the problem of radio channel allocation in wireless IP (Internet protocol) multimedia networks. The project will develop resource allo ....Intelligent Resource Allocation Techniques for Next Generation Wireless Mobile Communication Networks. The project will develop radio and network resource allocation techniques to maximise network utilisation and to offer guaranteed Quality of Service (QoS) for multimedia traffic in 3G/4G wireless mobile communication networks. In particular, this work will study the problem of radio channel allocation in wireless IP (Internet protocol) multimedia networks. The project will develop resource allocation algorithms based on traffic conditions, link qualities and service requirements using statistical traffic models, mobile software agents and neural network techniques.
Read moreRead less
Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this ....Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this relates to mice. Expected outcomes and benefits will be a new understanding of which aspects of fat metabolism are most influenced by androgens, and an ability to anticipate potential metabolic impacts of natural or pharmacological fluctuations in androgen levels in humans, laboratory animals and livestock.Read moreRead less
Special Research Initiatives - Grant ID: SR0354675
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Australian Communications Research Network (ACoRN). Information and Communication Technology is a key contributor to national productivity and growth. ACoRN aims to stimulate creativity, innovation and breakthrough science, leading to technological advancement in telecommunications. The focus is on development of fundamental theories for application to emerging wired and wireless communications technologies. Specific objectives include consolidation of existing linkages; facilitation of multidis ....Australian Communications Research Network (ACoRN). Information and Communication Technology is a key contributor to national productivity and growth. ACoRN aims to stimulate creativity, innovation and breakthrough science, leading to technological advancement in telecommunications. The focus is on development of fundamental theories for application to emerging wired and wireless communications technologies. Specific objectives include consolidation of existing linkages; facilitation of multidisciplinary research; formation of new links; stimulation of commercial activity; improved post-graduate education; and increased International prominence. Our current vision involves a range of programs including: undergraduate occupational training, postgraduate internships, national and international visiting programs, and seed funding for collaborative proposals.Read moreRead less
ARC Communications Research Network. Building on a strong platform of existing research excellence, the Aim of the Network is to facilitate nation-wide collaborative research, promoting four intersecting research Themes: Mobile and Wireless Communications, Rural Communications, Broadband and Optical Networks, and Fundamentals of Emerging Media. Each Theme is formulated to drive multidisciplinary, innovative research as well as inspire new collaborative initiatives. Four Programs encapsulate the ....ARC Communications Research Network. Building on a strong platform of existing research excellence, the Aim of the Network is to facilitate nation-wide collaborative research, promoting four intersecting research Themes: Mobile and Wireless Communications, Rural Communications, Broadband and Optical Networks, and Fundamentals of Emerging Media. Each Theme is formulated to drive multidisciplinary, innovative research as well as inspire new collaborative initiatives. Four Programs encapsulate the core activities of the Network: Researcher Mobility, Workshops and Conferences, Postgraduate Education, and Knowledge Management Systems. The Network is expected to add significant value to pre-existing investments and raise the profile of Australian telecommunications research.Read moreRead less
Broadband to the bush: Polarization as a new resource in wireless cross-layer design. 'Broadband to the Bush' is a national priority - more than 1.6 million homes, small businesses and not-for-profit organizations in rural, regional, and remote Australia are set to benefit from broadband access to phone networks and the internet. The immediate challenges lie in overcoming poor download speeds and area coverage, as well as expensive access. This research will deliver cost and power-efficient re ....Broadband to the bush: Polarization as a new resource in wireless cross-layer design. 'Broadband to the Bush' is a national priority - more than 1.6 million homes, small businesses and not-for-profit organizations in rural, regional, and remote Australia are set to benefit from broadband access to phone networks and the internet. The immediate challenges lie in overcoming poor download speeds and area coverage, as well as expensive access. This research will deliver cost and power-efficient receiver architectures to provide end-user utility, and will train postgraduate researchers across traditional discipline boundaries in mathematics and engineering. The project represents an important contribution to frontier technologies in information and communications technology for building and transforming Australian industries.Read moreRead less
Mab Immunotherapies For Myeloid Leukemia Patients With Germline Or Somatic RUNX1 Mutations.
Funder
National Health and Medical Research Council
Funding Amount
$766,995.00
Summary
This proposal presents preliminary evidence and proposes to confirm that 2 cell surface molecules, CD11a (ITGAL) and IL3RA (CD123) are direct (probably repression) targets of RUNX1 in HSCs, and are dysregulated in RUNX1 mutated AML. Monoclonal antibody therapies that target these two surface molecules have already passed different clinical trial phases for different diseases. We plan to show these antibodies are effective in RUNX1 positive AML in preclinical models and then clinical trials.
Efficient Transmission Strategies for Cooperative Wireless Ad Hoc Networks. The contribution of information and communications technologies to the national economy has been widely recognized. It enables wealth creation, employment and exports, underpinning many innovation processes. Immediate project benefits will be: contribution to the knowledge base and fundamental capabilities in wireless communication; education of future Australian academic and industrial innovators; raising the internati ....Efficient Transmission Strategies for Cooperative Wireless Ad Hoc Networks. The contribution of information and communications technologies to the national economy has been widely recognized. It enables wealth creation, employment and exports, underpinning many innovation processes. Immediate project benefits will be: contribution to the knowledge base and fundamental capabilities in wireless communication; education of future Australian academic and industrial innovators; raising the international profile of Australian research in the area of information technology. The proposed research is in areas of great commercial interest, addressing new directions and technologies for future wireless networks. Applied development of the outcomes will lead to valuable intellectual property for commercial exploitation.Read moreRead less
Adaptive Broadband Wireless Communication. The contribution of Information and Communications Technologies to the National Economy has been widely recognized. ICT enables wealth creation, employment and exports, and underpins many innovation processes. Immediate project benefits will be: Contribution to the knowledge base and fundamental capabilities in broadband wireless communication; Education of future Australian academic and industrial innovators; Raising the international profile of Austr ....Adaptive Broadband Wireless Communication. The contribution of Information and Communications Technologies to the National Economy has been widely recognized. ICT enables wealth creation, employment and exports, and underpins many innovation processes. Immediate project benefits will be: Contribution to the knowledge base and fundamental capabilities in broadband wireless communication; Education of future Australian academic and industrial innovators; Raising the international profile of Australian research in the area of information technology. Applied development of the outcomes will lead to valuable intellectual property with potential for commercial exploitation. Close links to Australian industry ensures Australian ICT companies stand to gain commercial advantage.Read moreRead less
Cooperative Mesh Networks for Municipal Wireless Access. Robust mobile broadband data communication is vital for public safety and emergency services applications. This project will improve the performance and cost-effectiveness of mesh networks, enabling new network architectures. Immediate benefits to Australia will be: Contribution to a growing knowledge base and fundamental capabilities wireless broadband communications; Education of future leading academic and industrial innovators; Raising ....Cooperative Mesh Networks for Municipal Wireless Access. Robust mobile broadband data communication is vital for public safety and emergency services applications. This project will improve the performance and cost-effectiveness of mesh networks, enabling new network architectures. Immediate benefits to Australia will be: Contribution to a growing knowledge base and fundamental capabilities wireless broadband communications; Education of future leading academic and industrial innovators; Raising the international profile of Australian research in information technology. The contribution of Information and Communications Technology to the National economy is widely recognized. ICT contributes to wealth creation, employment and exports, underpinning many innovation processes.Read moreRead less