Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understan ....Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understanding of how decision-making evolves in healthy ageing, and a tool based on genetic scores and computational modelling to predict an individual's trajectory of cognitive function. This could help identify individuals who are at risk for cognitive decline, which could then inform better interventions.Read moreRead less
A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in ....A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in sound-to-meaning correspondences as probabilistic cues to attain spoken language. The outcome will be a better neural account of language comprehension and production. The benefit of this new account will be a stronger basis for assessment and treatment of developmental and acquired language impairments.Read moreRead less
Benchmarking the neurophysiology of human cortex models in vitro. This project aims to improve human brain models in vitro by developing an analytical tool benchmarking biophysical similarities to the adult human cortex. This project expects to generate new knowledge by testing for the first time the theory that integrating sensory-like inputs and awake/sleep-like cycles of electrical activity in vitro may complete the maturation of human brain organoid models. It will also generate new methods ....Benchmarking the neurophysiology of human cortex models in vitro. This project aims to improve human brain models in vitro by developing an analytical tool benchmarking biophysical similarities to the adult human cortex. This project expects to generate new knowledge by testing for the first time the theory that integrating sensory-like inputs and awake/sleep-like cycles of electrical activity in vitro may complete the maturation of human brain organoid models. It will also generate new methods to simplify the analysis of multimodal path-clamping data (Patch-seq). Expected outcomes will facilitate research collaboration and the reproducibility of accurate experimental replicates of the human brain. This will provide significant benefits in the global race to understand human brain computation mechanisms.Read moreRead less
A novel design approach for sustainable and resilient railway formations. The project aims to validate a novel design approach for more sustainable and resilient railway formations. The railway network underpins the Australian economy and its maintenance costs tens of millions of dollars every year. This cost will increase with the growing frequency and intensity of climatic events. The research will advance the knowledge on the effect of water on the performance of railway formations and will d ....A novel design approach for sustainable and resilient railway formations. The project aims to validate a novel design approach for more sustainable and resilient railway formations. The railway network underpins the Australian economy and its maintenance costs tens of millions of dollars every year. This cost will increase with the growing frequency and intensity of climatic events. The research will advance the knowledge on the effect of water on the performance of railway formations and will deliver a novel design tool for end-users that will allow engineers to recycle fouled ballast in formations . The project will yield significant financial benefits for Australia, will strengthen links between Academia and industry partners, and will address environmental and sustainability issues linked to fouled ballast.
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Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will ....Structural Fuses for Safer and More Economical Bridge Construction. This project aims to develop a novel structural system leading to more economical concrete bridge construction by utilising a customised structural fuse. A significant margin of safety is required in structural design to account for accidental over-loading and to reduce the risk of structural collapse. Such a margin leads to more material usage. Incorporation of a fuse into the structure that is triggered upon over-loading will cause a safer failure mode and prohibit further increase of loading, both of which result in a reduced structure without undermining safety. The project is expected to advance structural theory, and also provide significant benefits to the construction industry via cost reduction and more eco-friendly constructions.Read moreRead less
Bio-inspired Computing for Problems with Chance Constraints. Bio-inspired algorithms have successfully been applied to a wide range of optimisation problems. Uncertainties in real-world applications can lead to critical failures of production schedules or safe critical systems. Chance constraints model such uncertainties and allow to limit the possibility of such failures. This future fellowship builds up the area of bio-inspired computing for problems with chance constraints. It develops high ....Bio-inspired Computing for Problems with Chance Constraints. Bio-inspired algorithms have successfully been applied to a wide range of optimisation problems. Uncertainties in real-world applications can lead to critical failures of production schedules or safe critical systems. Chance constraints model such uncertainties and allow to limit the possibility of such failures. This future fellowship builds up the area of bio-inspired computing for problems with chance constraints. It develops high performing bio-inspired algorithms for stochastic problems where the constraints can only be violated with a small probability. The outcomes will lead to more effective and reliable optimisation methods for complex planning processes in areas of national priority such as mining and manufacturing.Read moreRead less
Evolutionary diversity optimisation. This project aims to build up and establish the area of evolutionary diversity optimisation. The project will cover the design and application of evolutionary diversity optimisation methods to complex problems of significance and high national economic benefit and build up the theoretical foundations of these methods. The project is expected benefit decision makers by providing them a diverse set of high quality alternatives to choose from. This project will ....Evolutionary diversity optimisation. This project aims to build up and establish the area of evolutionary diversity optimisation. The project will cover the design and application of evolutionary diversity optimisation methods to complex problems of significance and high national economic benefit and build up the theoretical foundations of these methods. The project is expected benefit decision makers by providing them a diverse set of high quality alternatives to choose from. This project will allow them to make highly informed decisions and lead to more reliable solutions for optimisation problems, in areas of high economic impact such as manufacturing and supply chain management.Read moreRead less
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100265
Funder
Australian Research Council
Funding Amount
$417,000.00
Summary
A closed-loop human–agent learning framework to enhance decision making. This project aims to design a foundational human–agent learning framework to augment the decision making process, using reinforcement and closed-loop mechanisms to enable symbiosis between a human and an artificial-intelligence agent. It envisages significant new technologies to promote controllability and efficient and safe exploration of an environment for decision actions – drastically boosting learning effectiveness and ....A closed-loop human–agent learning framework to enhance decision making. This project aims to design a foundational human–agent learning framework to augment the decision making process, using reinforcement and closed-loop mechanisms to enable symbiosis between a human and an artificial-intelligence agent. It envisages significant new technologies to promote controllability and efficient and safe exploration of an environment for decision actions – drastically boosting learning effectiveness and interpretability in decision making. Expected outcomes will benefit national cybersecurity by improving our understanding of vulnerabilities and threats involving decision actions, and by ensuring that human feedback and evaluations can help prevent catastrophic events in explorations of dynamic and complex environments.Read moreRead less
Next generation photonic waveguide sensors enabled by machine learning. This project aims to establish the next frontier in photonic waveguide sensing, by using machine learning to shift the complexity out of conventional photonic-waveguide/optical-fibre sensors and into smart detection algorithms. The complexity and instability of multimode photonic waveguides, traditionally a hinderance to sensing, will be advantageously employed to train deep learning models for sensing. Expected outcomes inc ....Next generation photonic waveguide sensors enabled by machine learning. This project aims to establish the next frontier in photonic waveguide sensing, by using machine learning to shift the complexity out of conventional photonic-waveguide/optical-fibre sensors and into smart detection algorithms. The complexity and instability of multimode photonic waveguides, traditionally a hinderance to sensing, will be advantageously employed to train deep learning models for sensing. Expected outcomes include the creation of intelligent photonic sensors that can, in principle, measure any environmental parameter using any optical waveguide material. It will create new critically needed measurement capabilities for challenging harsh environments, such as extreme temperature and in-vivo biochemical sensing.Read moreRead less