Discovery Early Career Researcher Award - Grant ID: DE170101514
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
The control of neuroplasticity in the brain. This project aims to determine how neuroplasticity – the brain’s ability to remodel and make new circuits – is controlled in both excitatory and inhibitory neurons. This capacity, vital for all cognitive functions, diminishes as people age. It is imperative to determine neuroplasticity’s mechanisms and how and why they change, but it is not known how both excitatory and inhibitory neurons contribute to neuroplasticity and how these dynamic alterations ....The control of neuroplasticity in the brain. This project aims to determine how neuroplasticity – the brain’s ability to remodel and make new circuits – is controlled in both excitatory and inhibitory neurons. This capacity, vital for all cognitive functions, diminishes as people age. It is imperative to determine neuroplasticity’s mechanisms and how and why they change, but it is not known how both excitatory and inhibitory neurons contribute to neuroplasticity and how these dynamic alterations are controlled. Understanding neuroplasticity is vital for learning, memory and healthy ageing throughout life.Read moreRead less
The Analog Mind: Connectionism, Consciousness and Mental Representation. The aim of our project is to explore novel conjectures about the way information is coded and processed in the brain, and the manner in which the brain manufactures consciousness. This work may eventually pay rich dividends by reducing the incidence of mental illnesses, such as schizophrenia, that disturb conscious experience. It may also lead to the development of more powerful forms of computation in artificial neural ne ....The Analog Mind: Connectionism, Consciousness and Mental Representation. The aim of our project is to explore novel conjectures about the way information is coded and processed in the brain, and the manner in which the brain manufactures consciousness. This work may eventually pay rich dividends by reducing the incidence of mental illnesses, such as schizophrenia, that disturb conscious experience. It may also lead to the development of more powerful forms of computation in artificial neural networks. This will have a significant impact on the artificial intelligence industry, with obvious economic benefits for Australia.
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Discovery Early Career Researcher Award - Grant ID: DE200101708
Funder
Australian Research Council
Funding Amount
$406,821.00
Summary
New directions for using brain stimulation to understand brain function. Neuroplasticity is of fundamental importance to brain function as it mediates learning, memory and development. Deficits in neuroplasticity are observed in a number of neurological conditions and thought to contribute to cognitive dysfunction. This study is designed to develop a better understanding of the neurochemical and genetic factors impacting on neuroplasticity. In addition, it aims to (i) upregulate brain connectivi ....New directions for using brain stimulation to understand brain function. Neuroplasticity is of fundamental importance to brain function as it mediates learning, memory and development. Deficits in neuroplasticity are observed in a number of neurological conditions and thought to contribute to cognitive dysfunction. This study is designed to develop a better understanding of the neurochemical and genetic factors impacting on neuroplasticity. In addition, it aims to (i) upregulate brain connectivity in a precise and targeted manner, (ii) elicit functional increases in cognitive performance and (iii) demonstrate the relationship between functional connectivity and cognition. Outcomes include a better understanding of plasticity in the brain & a enhanced capacity to examine and modulate brain plasticity.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100915
Funder
Australian Research Council
Funding Amount
$345,000.00
Summary
Uncovering the dynamics of object selection from movement trajectories. This project aims to establish the dynamic properties of selection for perception and action, and develop a computational model of object selection across perception and action. Everyday actions depend on isolating the relevant object (perceptual selection) and appropriate grasp (action selection). It was long thought that distinct and sequential stages of processing carried out perceptual and action selection, but recent fi ....Uncovering the dynamics of object selection from movement trajectories. This project aims to establish the dynamic properties of selection for perception and action, and develop a computational model of object selection across perception and action. Everyday actions depend on isolating the relevant object (perceptual selection) and appropriate grasp (action selection). It was long thought that distinct and sequential stages of processing carried out perceptual and action selection, but recent findings suggested that a single mechanism may subserve both. Through a two-pronged approach including rigorous empirical work and computational modelling, this project aims to study this fundamental aspect of human cognition.Read moreRead less
A unified theory of performance in absolute identification tasks. The ability to identify stimuli is fundamentally important in human cognition and is studied in absolute identification tasks, where people must identify one out of a number of stimuli, varying on a single dimension, with an appropriate label. A remarkable finding is that people cannot reliably identify more than about seven different stimuli. This limit imposes severe practical restrictions on our ability to categorise stimuli an ....A unified theory of performance in absolute identification tasks. The ability to identify stimuli is fundamentally important in human cognition and is studied in absolute identification tasks, where people must identify one out of a number of stimuli, varying on a single dimension, with an appropriate label. A remarkable finding is that people cannot reliably identify more than about seven different stimuli. This limit imposes severe practical restrictions on our ability to categorise stimuli and constitutes a perplexing problem for cognitive theory. This project involves an international collaborative effort by five leading researchers in mathematical psychology to develop a comprehensive, integrative model of human performance in absolute identification tasks.
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Unconscious processing: To what extent, how flexible and how smart? We are unaware of the sophisticated pattern analyses conducted by our perceptual systems that enable us to operate in a complex environment. Less clear is whether unconsciously presented information itself can influence our behaviour or indeed whether unconscious cognition occurs. The proposed studies provide the foundation and structure for a pioneering examination of the extent, flexibility and computational power of unconscio ....Unconscious processing: To what extent, how flexible and how smart? We are unaware of the sophisticated pattern analyses conducted by our perceptual systems that enable us to operate in a complex environment. Less clear is whether unconsciously presented information itself can influence our behaviour or indeed whether unconscious cognition occurs. The proposed studies provide the foundation and structure for a pioneering examination of the extent, flexibility and computational power of unconscious processing at the level of neural response and behaviour. The impact and benefits of the project will be in its contribution to theory with outcomes revealing the boundary conditions governing unconscious cognition and providing a first benchmark for how such conditions might vary across the lifespan.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100868
Funder
Australian Research Council
Funding Amount
$336,284.00
Summary
Neural mechanisms of inhibitory control of human speech in stutterers and non-stutterers. Stopping oneself from speaking is a crucial communication function. In people who stutter, a disorder of this function causes their debilitating speech problem. This project will use cutting edge neuroimaging techniques to reveal how the brain stops speech in stutterers and in fluent speakers.
Identifying Malingered Posttraumatic Stress Disorder: Biological Markers for Legal Assessment. Posttraumatic stress disorder (PTSD) is the most common psychiatric disorder that is claimed in compensation claims in Australia. There are currently no reliable means to distinguish malingered from genuine PTSD. This project aims to develop the most accurate means of identifying malingered PTSD by using the most recent technology to index biological responses, including fMRI, in participants with PT ....Identifying Malingered Posttraumatic Stress Disorder: Biological Markers for Legal Assessment. Posttraumatic stress disorder (PTSD) is the most common psychiatric disorder that is claimed in compensation claims in Australia. There are currently no reliable means to distinguish malingered from genuine PTSD. This project aims to develop the most accurate means of identifying malingered PTSD by using the most recent technology to index biological responses, including fMRI, in participants with PTSD, without PTSD, and malingered PTSD. This study will lead to a biological assessment that can objectively index PTSD and be resistant to intentional feigning. These data will significantly enhance legal assessments of PTSD and facilitate compensation resolution.Read moreRead less
Models of Knowledge Restructuring. In a world of rapid change, people must frequently adapt cognitive skills to new technologies. This often requires restructuring of knowledge, from simple initial strategies to increasingly complex ways of mastering the task. This is not always easy and people sometimes resist knowledge restructuring. We present a network model of knowledge restructuring that combines attentional processes with error-driven learning. The model accounts for several existing resu ....Models of Knowledge Restructuring. In a world of rapid change, people must frequently adapt cognitive skills to new technologies. This often requires restructuring of knowledge, from simple initial strategies to increasingly complex ways of mastering the task. This is not always easy and people sometimes resist knowledge restructuring. We present a network model of knowledge restructuring that combines attentional processes with error-driven learning. The model accounts for several existing results and makes predictions that guide the proposed research. Three factors will be examined empirically: (1) the role of directing attention to alternative strategies; (2) the imperfection of existing knowledge; and (3) the complexity of alternative strategies.Read moreRead less
Brain mechanisms for coordinating with others through sound. Distinguishing between sounds produced by self and others is critical for interpersonal coordination and communication through speech and music. This project employs a novel dual-brain electrophysiological technique with tagged audio signals to elucidate how the human brain achieves this distinction, and when and why it cannot. Expected outcomes include new knowledge on the neurophysiological mechanisms that support self-other processi ....Brain mechanisms for coordinating with others through sound. Distinguishing between sounds produced by self and others is critical for interpersonal coordination and communication through speech and music. This project employs a novel dual-brain electrophysiological technique with tagged audio signals to elucidate how the human brain achieves this distinction, and when and why it cannot. Expected outcomes include new knowledge on the neurophysiological mechanisms that support self-other processing, and the acoustic conditions and behavioural strategies that facilitate their operation. These outcomes should ultimately have applied benefits for improving interpersonal coordination and social interaction, especially in digital environments and clinical populations with atypical self-other processing.Read moreRead less