Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Resolving the warming East Australian Current's impact on a marine food web. Resolving the warming East Australian Current's impact on a marine food web. This project aims to understand the effects of climate change on marine food webs, from plankton production to predation by iconic marine fauna, by integrating data on oceanographic conditions and fish distribution with the foraging patterns and breeding success of seabirds. Warming waters due to strengthening western boundary currents have unk ....Resolving the warming East Australian Current's impact on a marine food web. Resolving the warming East Australian Current's impact on a marine food web. This project aims to understand the effects of climate change on marine food webs, from plankton production to predation by iconic marine fauna, by integrating data on oceanographic conditions and fish distribution with the foraging patterns and breeding success of seabirds. Warming waters due to strengthening western boundary currents have unknown consequences for coastal marine food webs. Innovative prey capture signatures from accelerometers, and advanced movement models from satellite locations will show how predators locate and prey upon fish schools. Anticipated outcomes are insight into how changing resource availability in the oceans affects ecosystem resilience; improved viability for coastal industries; and ecosystem-based conservation management strategies.Read moreRead less
Everyday Heritage. This project aims to uncover everyday but overlooked forms of Australian heritage. Working collaboratively to bridge academic and industry practice, it seeks to develop innovative methods with outcomes expected to include enhanced collaboration between heritage, digital humanities, and historical research, and new resources for communities and the heritage sector. This should provide significant social and cultural benefits such as more inclusive forms of heritage, and broader ....Everyday Heritage. This project aims to uncover everyday but overlooked forms of Australian heritage. Working collaboratively to bridge academic and industry practice, it seeks to develop innovative methods with outcomes expected to include enhanced collaboration between heritage, digital humanities, and historical research, and new resources for communities and the heritage sector. This should provide significant social and cultural benefits such as more inclusive forms of heritage, and broader intellectual and practical understandings of shared history and citizenship. The project will promote public debate on the role of the past in modern Australia through a range of new forms of history and heritage, digital resources and heritage management tools.
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Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge mic ....Visualising neuron-glia interactions in the injured central nervous system. The adult brain and spinal cord recovery poorly from injury. Attempts to overcome this problem include methods to promote the intrinsic regenerative capacity of injured neurons, and modulating the inhibitory extracellular environment to become permissive to regeneration. The goal of this project is to investigate an endogenous regenerative mechanism in the injured brain. This project will use the latest, cutting-edge microscopy techniques to visualise whether the endogenous astrocyte protein metallothionein can promote regeneration in the injured nervous system of living zebrafish. The successful outcomes of this project will provide significant insight into understanding how the brain responds to injury.Read moreRead less
Criminalisation of poverty and homelessness in Australia: A national study. The project aims to assess the policing and enforcement of public order crimes and related offences (e.g. obstruct/disobey police, breach of bail, and minor property offences) on individuals experiencing poverty and homelessness. The project endeavours to collect and analyse qualitative data from across Australia on the lived experience of people who are homeless or at risk of homelessness, regarding the impact of crimin ....Criminalisation of poverty and homelessness in Australia: A national study. The project aims to assess the policing and enforcement of public order crimes and related offences (e.g. obstruct/disobey police, breach of bail, and minor property offences) on individuals experiencing poverty and homelessness. The project endeavours to collect and analyse qualitative data from across Australia on the lived experience of people who are homeless or at risk of homelessness, regarding the impact of criminal laws and police powers concerned with presence in, and movement around public places. It will particularly focus on the impact on women, children and Indigenous peoples. The outcomes will seek to reduce the criminalisation of homeless people, by identifying law and policy reform options, and comparing their cost with that of 'business as usual'.Read moreRead less
Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100017
Funder
Australian Research Council
Funding Amount
$1,231,000.00
Summary
Networked knowledge for repatriation communities. This project aims to build a digital facility that supports the repatriation of Indigenous human remains. Repatriation contributes to reconciliation and Indigenous healing and wellbeing, and has been the most important agent of change in the relationship between Indigenous peoples, museums and the academy over the past 40 years. Successful repatriation requires and produces research materials diverse in type, geography and accessibility. Within a ....Networked knowledge for repatriation communities. This project aims to build a digital facility that supports the repatriation of Indigenous human remains. Repatriation contributes to reconciliation and Indigenous healing and wellbeing, and has been the most important agent of change in the relationship between Indigenous peoples, museums and the academy over the past 40 years. Successful repatriation requires and produces research materials diverse in type, geography and accessibility. Within an Indigenous data-governance framework, this project will gather, preserve and make accessible a critical and extensive record of repatriation information worldwide. The project is expected to support repatriation practice and scholarship and improve the opportunities of repatriation for social good.Read moreRead less