Comparative Effectiveness Of Breast Tomosynthesis And Mammography In Real-world Population Screening: Evidence To Underpin And Improve Breast Cancer Screening
Funder
National Health and Medical Research Council
Funding Amount
$1,851,430.00
Summary
This research addresses key evidence gaps in breast cancer screening by investigating tomosynthesis (3D mammography) versus standard 2D mammography screening to establish the effectiveness of tomosynthesis in Australia and internationally, including impact on cancers not detected at screening that progress clinically. Large-scale studies will be done in real world screening services including a prospective comparative study planned collaboratively with BreastScreen to guide screening policy.
Emerging Techniques For Earlier Diagnosis And Assessment Of Severity And Progression Of Artificial Stone Silicosis
Funder
National Health and Medical Research Council
Funding Amount
$994,642.00
Summary
Stonemasons who have worked with engineered stone have been shown to develop a rapidly progressive and potentially fatal form of silicosis. This research will use data from affected workers from Victoria, Western Australia and Queensland. The research will comprise a suite of projects to investigate many uncertainties related to radiological screening methods, as well as investigating new methods to assess disease severity and identify indicators of progression to inform future practice.
Two-Eyed Seeing – A Framework For Cultural Fishery Assessments Supporting Equitable And Sustainable Access To Shared Resources In NSW Inland Rivers
Funder
Fisheries Research and Development Corporation
Funding Amount
$1,460,500.00
Summary
Fish are totemic and a primary food source; and so are part of the deep cultural, spiritual and economic connections Aboriginal communities have to their waterways that are part of ‘Country’. Cultural knowledge tells us that when there’s more water availability cultural fishers experience increased total catches and greater diversity of target species, and they fish more (e.g. increase in recreational and subsistence fishing). These narratives also suggest that as a result of these improved cult ....Fish are totemic and a primary food source; and so are part of the deep cultural, spiritual and economic connections Aboriginal communities have to their waterways that are part of ‘Country’. Cultural knowledge tells us that when there’s more water availability cultural fishers experience increased total catches and greater diversity of target species, and they fish more (e.g. increase in recreational and subsistence fishing). These narratives also suggest that as a result of these improved cultural fishing opportunities, there are flow on socio-economic benefits to household budgets, diets of communities, social behaviours and mental health and well-being.
Water is sacred and living; and central to the cultural, social and spiritual identity of Aboriginal people, as well as to their livelihoods. Conceptual models underpinning western water management frameworks and decision making do not incorporate Aboriginal/First Nations socio-cultural complexity, local knowledge and governance arrangements. These are critical – Aboriginal/First Nations people have strong connections with fish, water, rivers and knowledge to contribute to planning, as well as a fundamental right to participate. Water and fish are central to the way of life, two-way knowledge and planning frameworks will support reciprocity in engagement and participation.
Two-Eyed Seeing Frameworks (Ganma, Yolgnu for two-ways) provide a way forward for cultural fishery assessments supporting equitable and sustainable access to shared resources. In this framework, knowledge systems (western and cultural) contribute in parallel, on an equal footing, and both serve as evidence bases to produce an enriched picture of mutual understanding. Application of this framework can empower Aboriginal communities to participate more equitably and negotiate by using their science and values and providing a method for inclusion.
The overall objective of this proposed project is to empower Aboriginal communities through application of a “Two-Eyed seeing framework” (Reid et al. 2020) to participate more equitably and negotiate for cultural fishing practices and water allocation and management. This project will define the cultural fishery and quantify the socio-economic value of cultural fishing in two NSW river regions, and assist communities to identify water management needs for key cultural fish species to support ongoing planning and negotiations. It will improve our current fishery and water management by providing a pathway for cultural fisheries and cultural science to be included. Overall, it will increase our current knowledge of fish and fisheries, by bridging the gap between cultural science and western science practitioners and knowledge holders to share understandings, insights and skills. The application and extension of this framework to a national project will be considered for future use in addressing cultural fishery allocations and management.
Objectives: 1. Identify suitable NSW riverine cultural fisheries, engage with Aboriginal Communities, Traditional Owners, codesign the project and confirm move to phase 2. 2. Define and quanitfy the cultural fishery and associated totemic, cultura and social values 3. Identify and describe fish objectives and water management needs for cultural fish species using the Fish and Flows Framework. 4. Determine if changes in (2) are related to changes in water availability, policy and operations and/or river restoration activities (e.g. fish passage restoration, cold water passage, screening), if possible. 5. Objectively assess the efficacy and utility of the “Two-Eyed Seeing framework” in assessing the totemic, culutal and social fishing values and linking them to the fish and flows framework, including consideration of National applicability. Read moreRead less
Designer solvents to control reaction outcome. This project aims to control outcomes of chemical reactions using specifically designed ionic liquids as solvents. Ionic liquids are distinct from molecular solvents and are underused due to the limited understanding of their effects on chemical processes. We are developing a predictive framework to explain such effects and this project aims to exploit this new knowledge, using both new and rarely applied ionic liquids to control reaction outcomes. ....Designer solvents to control reaction outcome. This project aims to control outcomes of chemical reactions using specifically designed ionic liquids as solvents. Ionic liquids are distinct from molecular solvents and are underused due to the limited understanding of their effects on chemical processes. We are developing a predictive framework to explain such effects and this project aims to exploit this new knowledge, using both new and rarely applied ionic liquids to control reaction outcomes. The significance lies in the ability to optimise reaction outcomes without the need for solvent screening. The innovation lies in the measurement of microscopic interactions between solvent and reagents, and the use of these interactions to affect a given process.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL200100049
Funder
Australian Research Council
Funding Amount
$2,906,992.00
Summary
Nanofluidic Membranes for Sustainable Energy Future. This project aims to create a novel class of advanced membranes by making fundamental breakthroughs in nanofluidics, and harnessing this for developing new renewable energy and low-energy separation technologies. This project addresses the key challenges in understanding selective mass transport at the angstrom scale, thereby allowing the development of innovative materials design strategies to realise the ultrafast molecular and ionic permeat ....Nanofluidic Membranes for Sustainable Energy Future. This project aims to create a novel class of advanced membranes by making fundamental breakthroughs in nanofluidics, and harnessing this for developing new renewable energy and low-energy separation technologies. This project addresses the key challenges in understanding selective mass transport at the angstrom scale, thereby allowing the development of innovative materials design strategies to realise the ultrafast molecular and ionic permeation, and the ultrahigh selectivities observed in biological cell membranes. This new cross-disciplinary research will benefit Australia by the development of new materials for accelerating renewable hydrogen and biofuel futures, and enabling sustainable production of energy materials.Read moreRead less
Phase stability of biomass fast pyrolysis bio-oil: behaviour and control. This project aims to carry out a systematic investigation into the phase behaviour and control of biomass fast pyrolysis into bio-oil and its derived fuels. The project addresses the major problem of fuel phase separation during processing and handling that cause significant operational challenges, for example pumping difficulties and line clogging, during storage, transport and applications of these fuels. The outcomes in ....Phase stability of biomass fast pyrolysis bio-oil: behaviour and control. This project aims to carry out a systematic investigation into the phase behaviour and control of biomass fast pyrolysis into bio-oil and its derived fuels. The project addresses the major problem of fuel phase separation during processing and handling that cause significant operational challenges, for example pumping difficulties and line clogging, during storage, transport and applications of these fuels. The outcomes include the discovery of fundamental knowledge on the phase structure, stability and behaviour of the products of biomass fast pyrolysis bio-oil and its derived fuels and the development of essential engineering tools for predicting and controlling phase behaviour and stability of these fuels.Read moreRead less
Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world ....Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world and our experience of the world, and aims to reconcile the two by bridging the gap between lived experience and scientific findings. The project will provide a range of ways of bridging the tension between these physical theories with our lived experience.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100449
Funder
Australian Research Council
Funding Amount
$453,000.00
Summary
High-performance ammonia electrosynthesis devices. The project aims to develop a robust process for electrosynthesis of ammonia using devices manufactured by Melbourne company Jupiter Ionics P/L and innovative electrolyte components. Towards this aim, tailored ion-shuttling compounds need to be designed and investigated to enable continuous generation of ammonia in scaled-up flow devices. This is expected to generate new knowledge in practical electrochemistry, catalysis and sustainable synthesi ....High-performance ammonia electrosynthesis devices. The project aims to develop a robust process for electrosynthesis of ammonia using devices manufactured by Melbourne company Jupiter Ionics P/L and innovative electrolyte components. Towards this aim, tailored ion-shuttling compounds need to be designed and investigated to enable continuous generation of ammonia in scaled-up flow devices. This is expected to generate new knowledge in practical electrochemistry, catalysis and sustainable synthesis. Key project outcome is a technology for production of ammonia from renewables that is pollution-free and highly scalable in contrast to the current process. Resulting benefit to Australian agriculture businesses is a method for distributed fertiliser generation without the use of fossil fuels.Read moreRead less
ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the ....ARC Centre of Excellence in Exciton Science. This Centre aims to manipulate the way light energy is absorbed, transported and transformed in advanced molecular materials. The research programme spans high-throughput computational screening, single molecule photochemistry and ultrafast spectroscopy and embraces innovative outreach and commercial translation activities. The Centre plans to capture the knowledge generated as new intellectual property, materials processing know-how, and through the creation of new employment opportunities. The expected outcomes and benefits include new Australian technologies in solar energy conversion, energy-efficient lighting and displays, security labelling and optical sensor platforms for defence.Read moreRead less