Exploring The Role Of Respiratory Virus Infections In Childhood Asthma Exacerbations
Funder
National Health and Medical Research Council
Funding Amount
$596,649.00
Summary
The PEAK study will explore the reasons children get worse asthma symptoms when they get colds. These reasons examined include the asthma medications taken (or not taken), allergies and exposure to allergens and the type of virus involved. The study follows the children over the whole school term and uses a new way to sample virus by collecting it in the breath, this is more comfortable than old methods and can be done at home.
Information Encoding By Temporal Structure Of Afferent Spike Trains
Funder
National Health and Medical Research Council
Funding Amount
$231,175.00
Summary
Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreve ....Our ability to sense, discriminate and interpret touch stimuli underpins some of the most crucial functions of the human hand that relate to object exploration and manipulation. The fundamental mechanism of how nerve impulses generated by tactile receptors are interpreted by the nervous system is not understood. Only by discovering the underlying neural encoding mechanisms can we appreciate the functional impairments in patients and learn to identify them before they become widespread and irreversible.Read moreRead less
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
A Multi-national Trial To Predict Treatment Response In Subtypes Of Depression
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Treatment of MDD using trial and error can have serious consequences. It can prolong the patient’s suffering (depression is associated with substantial morbidity, and mortality), prolong their absence from work and other productive activity and increase the burden on their family-carers. This multi-national study will collect genetics, brain function and behavioural data from a large number of participants, allowing for sensitive predictors of response to be determined.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100050
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
Spacecraft Innovation Laboratory. The Australian Spacecraft Innovation Laboratory is designed to provide researchers and entrepreneurs with a venue to integrate and test their “cubesats”, satellites the size of a loaf of bread, and small payloads. By centralising the satellite integration function, the standard of Australian space assets can be assured, giving researchers confidence that their spacebased experiments will succeed. Knowledge transfer to space start-ups will be accelerated by easin ....Spacecraft Innovation Laboratory. The Australian Spacecraft Innovation Laboratory is designed to provide researchers and entrepreneurs with a venue to integrate and test their “cubesats”, satellites the size of a loaf of bread, and small payloads. By centralising the satellite integration function, the standard of Australian space assets can be assured, giving researchers confidence that their spacebased experiments will succeed. Knowledge transfer to space start-ups will be accelerated by easing their access to space.
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Surviving in a toad-colonised landscape: manipulating predator behaviour to reduce the impact of the cane toad invasion. Invasive species pose a major threat to biodiversity; and within Australia, cane toads are widely viewed as one of the biggest such problems. Vigorous attempts at toad control have failed to slow the invasion front, and toads are now entering the Kimberley region. If we can’t stop the toads, are there other ways to reduce the numbers of native predators killed by eating thes ....Surviving in a toad-colonised landscape: manipulating predator behaviour to reduce the impact of the cane toad invasion. Invasive species pose a major threat to biodiversity; and within Australia, cane toads are widely viewed as one of the biggest such problems. Vigorous attempts at toad control have failed to slow the invasion front, and toads are now entering the Kimberley region. If we can’t stop the toads, are there other ways to reduce the numbers of native predators killed by eating these poisonous invaders? Predators given nausea-inducing chemicals with their first toad meal rapidly learn to avoid cane toads as prey, enabling them to survive even where toads are present. The study will develop those methods for several vulnerable native species, including techniques for deployment of aversion-inducing baits in advance of the toad invasion.Read moreRead less
Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. Th ....Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. The success of this project will further enhance the international competitiveness of Australian research in this important field and will benefit any Australian industry and business where software systems are deeply-rooted, such as transportation, smart homes, medical devices, defence and finance.Read moreRead less
Non-equilibrium reacting shock layers. This project aims is to study the non-equilibrium aerodynamic processes involved in hypervelocity flight. The design of vehicles for high speed flight is critically dependent on modelling the interactions between the flow field and the airframe, and the current lack of understanding is restricting the scope and benefit of viable activities in space. The expected outcomes include the ability to design optimised heat shields and air-frames with minimum mass a ....Non-equilibrium reacting shock layers. This project aims is to study the non-equilibrium aerodynamic processes involved in hypervelocity flight. The design of vehicles for high speed flight is critically dependent on modelling the interactions between the flow field and the airframe, and the current lack of understanding is restricting the scope and benefit of viable activities in space. The expected outcomes include the ability to design optimised heat shields and air-frames with minimum mass and maximum payload, precisely targeting specific flight conditions and vehicle shapes. The prospective benefits include increased productivity and reliability and reduced cost of missions to and from space, and a proliferation of new applications which this understanding will facilitate.Read moreRead less
Global Lithospheric Architecture Mapping II. The continents have been rifted, or broken up, and collided, or re-assembled, along major zones of weakness many times throughout Earth's history. Boundaries between such continental domains focus large-scale movements of fluids that can produce giant ore deposits. This study will provide new perspectives on the localisation of world-class economic deposits, the Earth resources on which society depends. Innovations in imaging the deep Earth beneath co ....Global Lithospheric Architecture Mapping II. The continents have been rifted, or broken up, and collided, or re-assembled, along major zones of weakness many times throughout Earth's history. Boundaries between such continental domains focus large-scale movements of fluids that can produce giant ore deposits. This study will provide new perspectives on the localisation of world-class economic deposits, the Earth resources on which society depends. Innovations in imaging the deep Earth beneath continents, and in numerical modelling, will maintain our high international profile in research relevant to National Priority 1.6 (Developing Deep Earth Resources). Unique 3D geological maps of regions down to 250km will make the composition of deep Earth regions newly accessible to geoscientists and all potential endusers.Read moreRead less