Discovery Early Career Researcher Award - Grant ID: DE240100635
Funder
Australian Research Council
Funding Amount
$448,801.00
Summary
Understanding the development of lifestyle behaviours in early childhood. This project adopts novel statistical modelling and machine learning approaches to understand the development of lifestyle behaviours in early childhood. Despite the pivotal role of lifestyle behaviours in influencing health and quality of life, little research exists on lifestyle behaviours in early childhood. This project will establish a comprehensive understanding of lifestyle behaviours in early childhood by identifyi ....Understanding the development of lifestyle behaviours in early childhood. This project adopts novel statistical modelling and machine learning approaches to understand the development of lifestyle behaviours in early childhood. Despite the pivotal role of lifestyle behaviours in influencing health and quality of life, little research exists on lifestyle behaviours in early childhood. This project will establish a comprehensive understanding of lifestyle behaviours in early childhood by identifying key developmental time points, mechanisms of behavioural change, and children at risk of developing poor lifestyle behaviours. The project will inform strategies and policies to optimise lifestyle behaviours from the start of life and showcase the capabilities of novel methods in advancing behavioural epidemiology.Read moreRead less
Dust-related Disease In WA: Asbestos, Silica And Diesel Exposures, Lifestyle Factors And Genetic Predisposition.
Funder
National Health and Medical Research Council
Funding Amount
$567,226.00
Summary
This multi-factorial project will extend the follow-up of 4 large, established groups of people who have experienced significant exposure to asbestos, silica or diesel, either through their jobs, or environmentally. Mesothelioma, lung cancer and prostate cancer are common among these groups. The study will provide important information on the effects of different levels of exposure to these three cancer-causing agents, as well as their effects on chronic respiratory diseases such as asbestosis, ....This multi-factorial project will extend the follow-up of 4 large, established groups of people who have experienced significant exposure to asbestos, silica or diesel, either through their jobs, or environmentally. Mesothelioma, lung cancer and prostate cancer are common among these groups. The study will provide important information on the effects of different levels of exposure to these three cancer-causing agents, as well as their effects on chronic respiratory diseases such as asbestosis, silicosis, asthma and tuberculosis. Ways in which these diseases may be prevented through the diet and other lifestyle habits (including smoking, alcohol consumption and exercise), will be closely examined. This study will also help to identify the genes which may place some people at a higher risk than others.Read moreRead less
Risk Factors For Asthma, Chronic Bronchitis And Emphysema In Older Adults
Funder
National Health and Medical Research Council
Funding Amount
$330,574.00
Summary
Chronic obstructive pulmonary disease (including chronic bronchitis and emphysema) is a major public health problem in Australia. The main known cause is cigarette smoking, which peaked among Australian men shortly after the second world war. Now that the consequences of this epidemic of smoking are passing, more attention needs to be paid to other causes of the condition. The proposed study will focus on occupational and domestic exposures and dietary factors in older people. Dusty jobs have lo ....Chronic obstructive pulmonary disease (including chronic bronchitis and emphysema) is a major public health problem in Australia. The main known cause is cigarette smoking, which peaked among Australian men shortly after the second world war. Now that the consequences of this epidemic of smoking are passing, more attention needs to be paid to other causes of the condition. The proposed study will focus on occupational and domestic exposures and dietary factors in older people. Dusty jobs have long been associated with COPD. However it is not known to what extent other occupational exposures to fumes and vapours are also responsible. Identifying such jobs would lead to better workplace conditions and prevention of further cases. Workers who have already developed COPD could be more fairly compensated. Similarly if indoor exposures to tobacco smoke and unvented gas appliances were found to play a role, further controls on smoking, flues and improved ventilation could also prevent cases of COPD. It is generally thought that emphysema develops from an imbalance between the oxidative stresses on the lungs and protective enzymes. A diet high in antioxidant vitamins and fish may protect against the development of COPD. If confirmed by this study, it would then be possible to conduct clinical trials of supplementation in smokers at risk of developing COPD. Public nutritional education could reduce the incidence of the condition in the future.Read moreRead less
Determining The Affect And Cost Effectiveness Of Nutrition In Critically Ill Patients From Intensive Care Unit Admission To Hospital Discharge.
Funder
National Health and Medical Research Council
Funding Amount
$138,964.00
Summary
Nutrition when you are severely unwell is very important to support recovery. Research is required to determine exactly how much nutrition is needed in severely ill patients to ensure their best recovery. This project aims to determine what effect nutrition has on clinical and functional outcomes of patients who are severely ill during their whole hospital stay. It will also aim to determine the cost effectiveness of nutrition for these patients.
Dietary Therapies For The Treatment Of Drug-resistant Epilepsy
Funder
National Health and Medical Research Council
Funding Amount
$69,757.00
Summary
Epilepsy affects about 225,000 Australians, with 30% of suffers still experiencing seizures despite being on medications. A reduction in seizures can significantly improve the health of people with epilepsy who do not respond to medications. Low carbohydrate, high fat diets are a well-established treatment option in children, but this has not previously been studied in Australian adults. The aim of this research is to evaluate if dietary therapies are an effective treatment in adult epilepsy.
Targeted Nutrition To Improve Maternal And Child Health Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
Nutrition is vitally important to support the rapid growth and development occurring from conception to a child’s second birthday – the first 1000 days. Failure to meet nutritional needs during this critical period can have profound consequences for lifelong health. Through our CRE in Targeted Nutrition to Improve Maternal and Child Health Outcomes, we will provide nutritional interventions which optimise a mother’s health outcomes and ensure her children achieve their full potential.
Protein Absorption And Kinetics In Critical Illness
Funder
National Health and Medical Research Council
Funding Amount
$1,233,268.00
Summary
This experienced & productive group plan to perform a number of interrelated studies in patients with critical illness the aim of which will be to ascertain protein absorption & kinetics, & the relationship between protein intake & muscle physiology. The goal is to lay the groundwork for an understanding of protein in the nutritional support of these patients which will help us to later establish the optimum amount & type of protein to improve muscle strength, functional outcomes & survival.