Failure modes in ceramic-based layer structures: Relevance to failure of dental crowns. With the aging of our population, issues concerning the lifetime of biological system are paramount to the quality of life and economic well being of our society. This project is closely linked to the development of prosthetic materials and structures that will improve performance and life of biomechanical devices, by providing better understanding to the mechanics of failure and failure origins of ceramic-ba ....Failure modes in ceramic-based layer structures: Relevance to failure of dental crowns. With the aging of our population, issues concerning the lifetime of biological system are paramount to the quality of life and economic well being of our society. This project is closely linked to the development of prosthetic materials and structures that will improve performance and life of biomechanical devices, by providing better understanding to the mechanics of failure and failure origins of ceramic-based dental crowns and restorations, and to develop materials that will withstand exacting conditions - in body fluids - over extended lifetimes. Crown replacement is by far the most widespread of all prosthetic procedures. This project promises to help bridge the gap between physical and medical science in Australia. Read moreRead less
Flowable composite system with short S-glass fibre and halloysite nanotubes. Flowable composite system with short S-glass fibre and halloysite nanotubes. This project aims to design dental materials with reduced amalgams, using a strong but flowable composite with randomly distributed short S-glass fibres and a non-toxic natural nano-composite overlay. This alternative dental composite material is expected to meet international regulatory bodies’ intention to reduce amalgams. Using advanced phot ....Flowable composite system with short S-glass fibre and halloysite nanotubes. Flowable composite system with short S-glass fibre and halloysite nanotubes. This project aims to design dental materials with reduced amalgams, using a strong but flowable composite with randomly distributed short S-glass fibres and a non-toxic natural nano-composite overlay. This alternative dental composite material is expected to meet international regulatory bodies’ intention to reduce amalgams. Using advanced photonic and micro-mechanical techniques to make engineered material is also expected to enhance Australian manufacturing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100030
Funder
Australian Research Council
Funding Amount
$1,200,000.00
Summary
Advanced focused ion beam (FIB) / scanning electron microscopes (SEM) for nanometre scale characterisation and fabrication. These instruments are designed to provide fundamental insights into physical and biological systems though characterisation and fabrication of structures at nanometre length scales. These versatile platforms will support a wide range of projects covering three national research priority areas. These range from the characterisation of light alloys for improving and building ....Advanced focused ion beam (FIB) / scanning electron microscopes (SEM) for nanometre scale characterisation and fabrication. These instruments are designed to provide fundamental insights into physical and biological systems though characterisation and fabrication of structures at nanometre length scales. These versatile platforms will support a wide range of projects covering three national research priority areas. These range from the characterisation of light alloys for improving and building Australia's Aluminium, Magnesium and Titanium alloy industries, to the study of aerosol particles for improved pulmonary drug delivery for asthma patients, the development of advanced solar cells and the study of the integrated behaviour of the soil-microbe system for sustainable agriculture.Read moreRead less
Fibre-Polymer Composites With Graded Microstructure. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the current generation of spinal disk protheses (metal plates with springs/polymers as shock absorber ....Fibre-Polymer Composites With Graded Microstructure. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the current generation of spinal disk protheses (metal plates with springs/polymers as shock absorbers). Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. Therefore a strong social and economic imperative exists to develop engineering solutions to this problem.Read moreRead less
Determination of the Properties of Hyper-Elastic Materials by Deep Indentation. We seek to develop the scientific basis for the interpretation of the results of "deep" indentation testing of non-linear elastic (hyper-elastic) materials. Simple tests (such as indentation) produce complex strain fields. Interpretation of the resulting data in terms of stiffness, for example, requires a complex model of the deformation process that can be utilised to link the observed behaviour to the basic prope ....Determination of the Properties of Hyper-Elastic Materials by Deep Indentation. We seek to develop the scientific basis for the interpretation of the results of "deep" indentation testing of non-linear elastic (hyper-elastic) materials. Simple tests (such as indentation) produce complex strain fields. Interpretation of the resulting data in terms of stiffness, for example, requires a complex model of the deformation process that can be utilised to link the observed behaviour to the basic properties of interest. This project is dedicated to an understanding of the complex deformation associated with large strain indentation of hyper-elastic materials and structures, development of finite element based models for this deformation and creation of techniques for interpretation of the results of such indentation tests.Read moreRead less
Bioactive Polymers for Wound Healing Applications. VitroGroR is a growth factor complex which enhances cell growth and migration, and hence has great potential for treating wounds. Tissue Therapies, which holds the rights to commercialization of VitroGroR, is seeking to develop methods of delivering VitroGroR in its active form to the wound environment. Two solutions to this problem will be developed in this project; a bioactive bandage containing a novel combination of microspheres and a hydrog ....Bioactive Polymers for Wound Healing Applications. VitroGroR is a growth factor complex which enhances cell growth and migration, and hence has great potential for treating wounds. Tissue Therapies, which holds the rights to commercialization of VitroGroR, is seeking to develop methods of delivering VitroGroR in its active form to the wound environment. Two solutions to this problem will be developed in this project; a bioactive bandage containing a novel combination of microspheres and a hydrogel matrix, and secondly an in-situ polymerisable matrix for treatment of deep wounds. The growth factor complex will be protected from aggressive proteases through encapsulation within microspheres, and the use of MMP-inhibiting comonomers.Read moreRead less
Surface engineering of biomaterials for optimal bone bonding characteristics. The ideal bone-implant material is hydroxyapatite. Chemically similar to bone mineral, hydroxyapatite is capable of inducing bone ongrowth. An ideal surface coating for metal hip implants, plasma spraying has been the preferred commercial hydroxyapatite coating technique. Until recently, it was always presumed that the bioactivity of hydroxyapatite resulted from its surface chemistry. However, a recent study has shown ....Surface engineering of biomaterials for optimal bone bonding characteristics. The ideal bone-implant material is hydroxyapatite. Chemically similar to bone mineral, hydroxyapatite is capable of inducing bone ongrowth. An ideal surface coating for metal hip implants, plasma spraying has been the preferred commercial hydroxyapatite coating technique. Until recently, it was always presumed that the bioactivity of hydroxyapatite resulted from its surface chemistry. However, a recent study has shown that the bioactivity of HAp coatings strongly correlates with surface roughness on the scale of bone cells. This project will explore cell-attachment behaviour for hydroxyapatite coatings prepared by plasma spraying compared with engineered surface morphology/chemistry by microlithography and vapour coating.Read moreRead less
Functionally graded fibre-polymer composites: a novel material for spinal disk prostheses. Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. A strong social/economic imperative exists to develop engineering solutions to this problem. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucle ....Functionally graded fibre-polymer composites: a novel material for spinal disk prostheses. Chronic back pain affects a significant proportion of the population and is primarily caused by failure of the spinal disk. A strong social/economic imperative exists to develop engineering solutions to this problem. This project concerns the development of a novel fibre-polymer functionally graded composite material that mimics the structure of the spinal disk. The spinal disk comprises a soft core (nucleus) and a tough fibrous periphery (annulus). The graded composite approach of this proposal represents a significant advance over spinal fusion, and over the alternative spinal disk protheses in clinical use or in the patent literature.Read moreRead less
Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the k ....Photoactive Semiconducting Biopolymers. The basic aims of this project are to elucidate, manipulate, and utilise the unique chemical and physical properties of a class of biopolymers called the melanins. These materials are the only known solid state semiconducting biopolymers, and are non-toxic, biocompatible, and biodegradable. Their use as active components in biomimetic soft electonic, optoelectronic or photovoltaic devices, has not hitherto been demonstrated. It is anticipated that the key outcomes from the project will be a demonstration of biopolymer-based photoelectrochemical and solid-state p-i-n solar cells, and an improved understanding of the physics and chemistry of these important biological macromolecules.Read moreRead less
Engineering a silk fibroin based ear drum with optimum acoustic properties. This project will use new silk fibroin materials to develop ear drums with improved acoustic properties. This will lead to significant improvement in the quality of life of nearly 2.5 million people in Australia who are affected by hearing loss and further strengthen Australia's leading position in this area.