Enabling Technologies for Motion Corrected Positron Emission Tomography (PET) of Unanaesthetized Laboratory Animals. Small animal molecular imaging is a powerful tool in biological research and drug discovery. Anaesthesia is routinely used to avoid motion distortion, but can profoundly alter the biological process studied. This research will enable quantitative imaging of neurobiological phenomena in awake laboratory animals. It will create new opportunities for Australian basic researchers to ....Enabling Technologies for Motion Corrected Positron Emission Tomography (PET) of Unanaesthetized Laboratory Animals. Small animal molecular imaging is a powerful tool in biological research and drug discovery. Anaesthesia is routinely used to avoid motion distortion, but can profoundly alter the biological process studied. This research will enable quantitative imaging of neurobiological phenomena in awake laboratory animals. It will create new opportunities for Australian basic researchers to use innovative technology with expected high economic potential, and benefit small biotech companies by facilitating pre-clinical and clinical development of new pharmaceuticals. The new motion tracking and image reconstruction technologies developed will strengthen Australia's leading position in engineering and biomedical systems development.Read moreRead less
Advanced Interface Technologies for Computational Science & Simulation. The project will research novel computer vision technologies that enable the next generation of visualisation portals for scientific collaboration. The development of new computer vision tools is key to truly natural human-machine interaction. The research outcomes of this project directly align with National Research Priority 3: Frontier Technologies. It supports four of the five relevant priority goals - Breakthrough Scien ....Advanced Interface Technologies for Computational Science & Simulation. The project will research novel computer vision technologies that enable the next generation of visualisation portals for scientific collaboration. The development of new computer vision tools is key to truly natural human-machine interaction. The research outcomes of this project directly align with National Research Priority 3: Frontier Technologies. It supports four of the five relevant priority goals - Breakthrough Science, Frontier Technologies, Smart Information Use, and Promoting an Innovation Culture and Economy. Outcomes of this research are also relevant to Research Priority 4: Safeguarding Australia, and has direct applications to video surveillance technology. Significant commercial opportunities, including licensing and spin-offs exist.Read moreRead less
High resolution single particle analysis of biological macromolecules. One of the great challenges of cell biology is to increase the rate of atomic resolution structure determination, particularly of membrane proteins and macromolecular assemblies. The current rate-limiting step is high quality crystal production. Our goal is to prove that protein structures can be determined to atomic resolution by single-particle analysis. 3D structures will be produced by computationally aligning high-resolu ....High resolution single particle analysis of biological macromolecules. One of the great challenges of cell biology is to increase the rate of atomic resolution structure determination, particularly of membrane proteins and macromolecular assemblies. The current rate-limiting step is high quality crystal production. Our goal is to prove that protein structures can be determined to atomic resolution by single-particle analysis. 3D structures will be produced by computationally aligning high-resolution electron microscope images of individual, randomly oriented molecules. The importance of this project is highlighted by the fact over 120,000 protein sequences are already databased, a number set to increase rapidly as new genome sequencing projects are completed.
Read moreRead less
High-Fidelity Modelling for Robotic-Assisted Minimally Invasive Needle Insertion. This project will develop robotic-assisted needle insertion and greatly improve minimally invasive surgery. It will also enhance the establishment of intellectual property for Australian medicine and produce important benefits to the healthcare sector. The proposed symbiotic integration of the systems will advance modelling technologies, and further create new capabilities for a wide range of science and engineerin ....High-Fidelity Modelling for Robotic-Assisted Minimally Invasive Needle Insertion. This project will develop robotic-assisted needle insertion and greatly improve minimally invasive surgery. It will also enhance the establishment of intellectual property for Australian medicine and produce important benefits to the healthcare sector. The proposed symbiotic integration of the systems will advance modelling technologies, and further create new capabilities for a wide range of science and engineering applications. The established methodologies and systems will also provide great potential benefits in many other areas, including microbiology, life sciences and bio/nano-technology. The project's outcomes will further consolidate Australia's position in innovative technologies and international research and development.Read moreRead less
Intelligently Activated Sensor Clusters for E-Commerce Applications. This project will investigate intelligent management of large sensor clusters installed in mechanical structures for use in Electronic Commerce applications. Finding algorithms for optimised placement of remotely controlled power supply and the communication unit in each sensor cluster is the first aim. Development of a sensor management algorithm that process user inputs submitted through the Internet and that exploits past se ....Intelligently Activated Sensor Clusters for E-Commerce Applications. This project will investigate intelligent management of large sensor clusters installed in mechanical structures for use in Electronic Commerce applications. Finding algorithms for optimised placement of remotely controlled power supply and the communication unit in each sensor cluster is the first aim. Development of a sensor management algorithm that process user inputs submitted through the Internet and that exploits past sensor data is the second aim. Since there is no such system available in the market, the project will have strong impacts in E-Commerce applications and bridge instrumentation systems useful to a wider community also advancing the research in clustering and expert systems.Read moreRead less
Robotic gait assistive strategy for people with paraplegia: Generating balanced and human-like gait on a bipedal system. The outcomes of the project will contribute significantly to the fundamental understanding of bipedal mechanisms, robotics, and the dynamics of human gait. This research is unique in Australia and it will strengthen Australia's research standing in robotics and health-sciences. The immediate application of the outcomes will contribute significantly to the musculoskeletal and p ....Robotic gait assistive strategy for people with paraplegia: Generating balanced and human-like gait on a bipedal system. The outcomes of the project will contribute significantly to the fundamental understanding of bipedal mechanisms, robotics, and the dynamics of human gait. This research is unique in Australia and it will strengthen Australia's research standing in robotics and health-sciences. The immediate application of the outcomes will contribute significantly to the musculoskeletal and psychological health of people with spinal cord injury, as well as the basic locomotion capability around the house to carry out their daily tasks more independently and conveniently. Hence it will directly contribute to improving their quality of life and substantially reducing health-care costs and carer responsibilities in the community.Read moreRead less
Indium arsenic antimony (InAsSb) Quantum Dots for Mid-Infrared Lasers. This proposal will open a new area of research for mid-infrared laser devices. Any achievement from this project will benefit various academic and industrial communities, such as national security, environmental monitoring and spectroscopy. The outcomes of this research could create a new generation of high-performance mid-infrared lasers and put Australian researchers in the forefront of the development in this field.
Development of Advanced Detection Systems for Accelerator Mass Spectrometry. This project aims to expand significantly the range of isotopes available for accelerator mass spectrometry at the Australian National University to include the ability to detect manganese-53, nickel-59 and uranium-236 to ultra-sensitive concentrations. To achieve this, my extensive experience in fundamental nuclear physics will be exploited to develop a gas-filled magnet for the detection of mangnese-53 and nickel-59, ....Development of Advanced Detection Systems for Accelerator Mass Spectrometry. This project aims to expand significantly the range of isotopes available for accelerator mass spectrometry at the Australian National University to include the ability to detect manganese-53, nickel-59 and uranium-236 to ultra-sensitive concentrations. To achieve this, my extensive experience in fundamental nuclear physics will be exploited to develop a gas-filled magnet for the detection of mangnese-53 and nickel-59, and a time-of-flight detector to detect uranium-236. This project has applications in the topical areas of climate change and nuclear safeguards, as well as applications in the earth sciences and the management of nuclear waste.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989492
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Dynamic Texture Measurement Facility. A texture goniometer is an advanced tool for texture characterisation of steels, light alloys, nanomaterials, superconductors and minerals. The ability to conduct dynamic texture measurements will significantly enhance the effectiveness of four material-based research institutes at the University of Wollongong and at Deakin University, as well as collaborative research with BlueScope Steel. The research is directly aligned to the National Research Priority o ....Dynamic Texture Measurement Facility. A texture goniometer is an advanced tool for texture characterisation of steels, light alloys, nanomaterials, superconductors and minerals. The ability to conduct dynamic texture measurements will significantly enhance the effectiveness of four material-based research institutes at the University of Wollongong and at Deakin University, as well as collaborative research with BlueScope Steel. The research is directly aligned to the National Research Priority of Frontier Technologies for Building and Transforming Australian Industry. The equipment will provide a valuable resource for industries in the Illawarra region of NSW and in regional South-West Victoria.Read moreRead less
Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will signific ....Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will significantly benefit the mineral exploration industry as well as underwater detection of cables and ship wrecks.Read moreRead less