Coherent X-ray Science and Biophysics. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However, as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This program draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membrane protein ....Coherent X-ray Science and Biophysics. The twenty first century is said to be the century of biology. And there is no doubt that the development of our understanding of biological system is continuing at a massive rate. However, as our understanding deepens, we need to draw on the whole range of scientific disciplines to proceed. This program draws together a multidisciplinary team of world-leading scientists to address one the key questions in modern biology, the structure of a membrane protein. We will develop techniques based on the latest developments in theoretical physics & chemistry, imaging, biology and technology - including the new Australian Synchrotron - to create new approaches to structural biology.Read moreRead less
Dynamics of Multiscale Complex Systems. Australia has built a strong position in the science and applications of multiscale phenomena, especially in interdisciplinary fields. The project will advance this position in plasma and biomedical physics by making new discoveries, developing new methods of analyzing such systems, and applying them to achieve practical outcomes. It will underpin Australia's participation in NASA's $600M STEREO mission, and will lead to improved methods and technologies ....Dynamics of Multiscale Complex Systems. Australia has built a strong position in the science and applications of multiscale phenomena, especially in interdisciplinary fields. The project will advance this position in plasma and biomedical physics by making new discoveries, developing new methods of analyzing such systems, and applying them to achieve practical outcomes. It will underpin Australia's participation in NASA's $600M STEREO mission, and will lead to improved methods and technologies for brain function analysis and imaging, which will be commercialized via industry partnerships. It will contribute to national research goals, especially in Breakthrough Science, Frontier Technologies, Smart Information Use, and Promoting Innovation.Read moreRead less
Biologically-Inspired Recognition and Processing in Colloidal Systems. The proposed research will enhance the understanding of forces and adsorption in biologically-inspired synthetic systems, and thereby create new strategies for improving selective adsorption, stabilization, coagulation, and separation. The expected outcomes are: increased understanding of chiral interactions at surfaces, a technique for rapid measurement of surface selectivity, new and better agents for chiral separation, a ....Biologically-Inspired Recognition and Processing in Colloidal Systems. The proposed research will enhance the understanding of forces and adsorption in biologically-inspired synthetic systems, and thereby create new strategies for improving selective adsorption, stabilization, coagulation, and separation. The expected outcomes are: increased understanding of chiral interactions at surfaces, a technique for rapid measurement of surface selectivity, new and better agents for chiral separation, a reduction in the use of organic pollutants, new methods for colloidal processing that will enable the preparation of new materials, and new surface coatings for increasing the useful life-time of medical implants.Read moreRead less
Self organization in (bio)molecular systems: Simulating the folding and aggregation of peptides, proteins and lipids. Molecular self-assembly is a basic property of living systems. Most proteins fold spontaneously and then further self-organize into functional complexes, effectively biological machines. Understanding how this occurs is a fundamental theoretical challenge with widespread application. Work will focus on developing methodology to simulate, computationally, the folding and aggrega ....Self organization in (bio)molecular systems: Simulating the folding and aggregation of peptides, proteins and lipids. Molecular self-assembly is a basic property of living systems. Most proteins fold spontaneously and then further self-organize into functional complexes, effectively biological machines. Understanding how this occurs is a fundamental theoretical challenge with widespread application. Work will focus on developing methodology to simulate, computationally, the folding and aggregation of peptides, proteins, and lipids. The aim is to accurately predict the structures of small peptides in solution and to refine crude models of larger molecules (complexes). This will facilitate the development of peptide based therapeutics and is essential in exploiting the growing volume of genetic information in biology and medicine.Read moreRead less
Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised impor ....Quantum Information and Entanglement: a new framework for Science and Technology with quantum many-body systems. The expected outcome of the research program is a significant boost in the understanding of quantum many-body systems, which will reinforce Australia's competitiveness and international profile in aspects of breakthrough science and frontier technologies. By developing both the underpinning theory and innovative computational tools, and by applying them to problems of recognised importance, this program will have direct implications in areas of condensed matter physics, quantum statistical mechanics, particle physics, complex systems, quantum information science and technology, quantum computation, engineered quantum systems and nanotechnology. Read moreRead less
Multiscale modelling: Applications to the Biomedical Sciences. 1) Significant reductions in the costs of developing pharmaceutical treatments, 2) Substantial reduction in hospitalisation costs, 3) Improved treatment of wounds, a significant cause of chronic ill-health which presently costs the Australian HealthCare System A$500,000,000/year.
Environmental change, carbon cycling and human impact in tropical Australia. This fellowhip will provide the fundamental science outputs required to understand the complex linkages between terrestrial ecosystems, environmental change and human impact in the tropics - in Australia and globally - thereby assisting in
(i) predicting the response of tropical ecosystems to future environmental change and respond to the impacts of tropical climate variability
(ii) developing and validating method ....Environmental change, carbon cycling and human impact in tropical Australia. This fellowhip will provide the fundamental science outputs required to understand the complex linkages between terrestrial ecosystems, environmental change and human impact in the tropics - in Australia and globally - thereby assisting in
(i) predicting the response of tropical ecosystems to future environmental change and respond to the impacts of tropical climate variability
(ii) developing and validating methodologies for improved carbon sequestration, verifiable carbon accounting and emissions trading
(iii) achieving sustainability in the utilization of the natural resource base of tropical Australia by optimizing the balance between wealth creation and environmental impact
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The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced gen ....The genomic programming of complex organisms. The project will have far-reaching consequences in medicine, agriculture, biotechnology, engineering, information science and associated industries. It will provide a platform for the rationalization of genetic epidemiology and genetic improvement programs, the development of a wide range of new diagnostics and therapies, the development of new core technologies and practical approaches in genetics and genetic diversity, a framework for advanced genetic engineering, the development of new principles and systems for information storage and transmission, and the design of artificial systems capable of self-referential assembly in other environments.Read moreRead less
Closing the Future: New Foundations for the Physics of Possibility. The distinction between a fixed and an open future is deeply embedded in human thought, and also central to some of the most profound puzzles in contemporary physics. By revealing the human origins of out fundamental concepts of possibility in time, this project will enhance our understanding of one of the most basic features of our experience of the world, lay foundations for a new treatment of time and possibility in foundame ....Closing the Future: New Foundations for the Physics of Possibility. The distinction between a fixed and an open future is deeply embedded in human thought, and also central to some of the most profound puzzles in contemporary physics. By revealing the human origins of out fundamental concepts of possibility in time, this project will enhance our understanding of one of the most basic features of our experience of the world, lay foundations for a new treatment of time and possibility in foundamental physics, and throw important new light on the mysteries of the quantum world.Read moreRead less
Astrophotonics: exploiting a new technological frontier to probe back to the Dark Ages. Photonics, a key research strength in Australia, emerged from the telecommunications industry. But this exciting field has now begun to foster new scientific disciplines. One of the most recent is astrophotonics, a field at the interface of photonics and another Australian research strength, astronomy. Astrophotonics will deliver cutting-edge technologies to ensure Australia's astronomical lead in the next de ....Astrophotonics: exploiting a new technological frontier to probe back to the Dark Ages. Photonics, a key research strength in Australia, emerged from the telecommunications industry. But this exciting field has now begun to foster new scientific disciplines. One of the most recent is astrophotonics, a field at the interface of photonics and another Australian research strength, astronomy. Astrophotonics will deliver cutting-edge technologies to ensure Australia's astronomical lead in the next decade. These new facilities will serve as a vital stepping stone to the Giant Magellan Telescope, a $500M project promising enormous economic, engineering and scientific opportunities for Australia. Astrophotonics will also lead to innovative technology transfer to fields such as medical science, optical computing and sensor technology.Read moreRead less