Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989127
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of ....A High-Throughput Neutron Spectrometer for The Study of Atomic and Molecular Motion at ANSTO. Neutron scattering enables new science across a broad range of disciplines, and for this reason it is undergoing major expansion in the USA, Europe, Japan and Australia. Various diffactometers and spectrometers have recently been built at ANSTO, but an instrumental option for a high-throughput cross-discipline spectroscopy is urgently needed. Fortunately, it is fairly straightforward to add this type of option to an existing spectrometer that will broaden its user-base from specialised applications in physics to more general applications in physics, chemistry, materials-science and biology. This additional option provides a totally new way for Australian scientists to study atomic and molecular motions. Read moreRead less
Improved Nanoscale and Molecular Models for Nanostructured Carbons, and their Applications in Simulation of Confined Fluids. This project has a multitude of benefits for Australia, a key one of which is the promotion of cross-disciplinary interaction and collaboration to conduct leading edge research in a technologically important area. In addition the project will utilize two PhD students who will be trained in research, and gain a broad range of skills in this multifaceted project involving t ....Improved Nanoscale and Molecular Models for Nanostructured Carbons, and their Applications in Simulation of Confined Fluids. This project has a multitude of benefits for Australia, a key one of which is the promotion of cross-disciplinary interaction and collaboration to conduct leading edge research in a technologically important area. In addition the project will utilize two PhD students who will be trained in research, and gain a broad range of skills in this multifaceted project involving theory, simulation and experiment. The research, grounded in molecular fundamentals, will also lead to the development of advanced tools for adsorption process modelling, useful in process design and scale-up, and contribute to Goal 1 of National Priority Area 3: Frontier Technologies for Building and Transforming Australian Industries.Read moreRead less
High throughput engineering of genetically encodable fluorescent sensors of intracellular signalling networks. Understanding of biochemical processes in living organisms is central to biological research and drug discovery. At present, the field suffers from a chronic paucity of adequate observation methods. The proposed project represents an interdisciplinary effort to create approaches for real-time monitoring of complex cellular chemistries. This work will deliver novel technologies for use i ....High throughput engineering of genetically encodable fluorescent sensors of intracellular signalling networks. Understanding of biochemical processes in living organisms is central to biological research and drug discovery. At present, the field suffers from a chronic paucity of adequate observation methods. The proposed project represents an interdisciplinary effort to create approaches for real-time monitoring of complex cellular chemistries. This work will deliver novel technologies for use in diagnostics and drug development. It will provide vital information on the changes in cellular processes induced by malignant transformation, viral infection and aging. This work will generate both health and economic benefits for the community and have a positive impact on the international visibility of Australian biomedical research.Read moreRead less
Generation of peptidomimetic surfaces for biomaterials applications. Biomedical implants are increasingly being used for the treatment of a variety of ailments. This project will significantly contribute to the development of these bioengineered constructs, by introducing an innovative method for tailoring the nature of the surface of these materials with structures that mimic the response of biological surfaces. This technology has the potential to promote favourable interactions of cells with ....Generation of peptidomimetic surfaces for biomaterials applications. Biomedical implants are increasingly being used for the treatment of a variety of ailments. This project will significantly contribute to the development of these bioengineered constructs, by introducing an innovative method for tailoring the nature of the surface of these materials with structures that mimic the response of biological surfaces. This technology has the potential to promote favourable interactions of cells with biomedical implants, and an initial targeted application will be to use these bioengineered constructs in the treatment of preventable blindness and severe visual impairment, afflictions which affect over 180 million individuals worldwide.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347662
Funder
Australian Research Council
Funding Amount
$195,000.00
Summary
Laser Ablation System for Elemental Analysis and Tropical Environmental Research. This application seeks funding for a Laser Ablation system as a sample introduction system for the current Inductively Coupled Plasma Mass Spectrometer (LA-ICPMS). The proposed LA-ICPMS facility will provide a trace element analytical facility that will be used for research in northern Australia which will enhance and develop strong and sustainable collaborative partnerships in the areas of conservation biology, ....Laser Ablation System for Elemental Analysis and Tropical Environmental Research. This application seeks funding for a Laser Ablation system as a sample introduction system for the current Inductively Coupled Plasma Mass Spectrometer (LA-ICPMS). The proposed LA-ICPMS facility will provide a trace element analytical facility that will be used for research in northern Australia which will enhance and develop strong and sustainable collaborative partnerships in the areas of conservation biology, living resource management, tropical environmental science and resource development. The facility will not be simply providing a routine analytical service. It will be used to develop innovative approaches to environmental management and sustainable development and ensure a continued high level of research and research training which will contribute to regional development.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453524
Funder
Australian Research Council
Funding Amount
$321,456.00
Summary
The Centre for Advanced Light Microscopy: Equipment for in-vivo multiphoton microscopy and high-throughput confocal microscopy. The Centre for Advanced Light Microscopy was established with ARC RIEF funding and is currently experiencing overwhelming demand as the sole confocal provider for 260 researchers at multiple institutions in south-east Queensland. The present joint application of the Universities of Queensland and Southern Queensland seeks to build on the resounding success of the origi ....The Centre for Advanced Light Microscopy: Equipment for in-vivo multiphoton microscopy and high-throughput confocal microscopy. The Centre for Advanced Light Microscopy was established with ARC RIEF funding and is currently experiencing overwhelming demand as the sole confocal provider for 260 researchers at multiple institutions in south-east Queensland. The present joint application of the Universities of Queensland and Southern Queensland seeks to build on the resounding success of the original initiative by introducing state-of-the-art confocal and multiphoton applications. This powerful platform technology will allow structural and functional information to be obtained from sensitive live samples with unprecedented spatial and temporal resolution, augmenting and accelerating vital research in the biosciences.
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From structures to systems: A hierachical approach to understanding sub-cellular components. This program will dramatically extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Au ....From structures to systems: A hierachical approach to understanding sub-cellular components. This program will dramatically extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation techniques in biomolecular systems, which are widely used within the chemical and pharmaceutical industries for modelling processes ranging from protein-drug interactions to the phase behaviour of lipids and surfactants. Read moreRead less
Increasing the Efficiency of Biomolecular Simulations. This program will extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation t ....Increasing the Efficiency of Biomolecular Simulations. This program will extend the range of biomolecular systems that can be modelled with near atomistic precision. It will provide a better understanding of the structure and function of proteins involved in the regulation of membrane fusion and fission as well as shedding light on the assembly of large-scale protein-protein and protein-membrane complexes in general. The work will help place Australia at the forefront of developing simulation techniques in biomolecular systems, which are widely used within the chemical and pharmaceutical industries. It will also provide opportunities for the training and development of young Australian researchers with top European laboratories. Read moreRead less
Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these w ....Patterned assemblies of molecules on surfaces. Because of their redox and photophysical properties, artificial porphyrin systems have been designed for applications such as light-harvesting antennae, catalysts and sensors. Control of molecular orientation is required in order to construct practical devices, and in this project methods of assembling porphyrins on surfaces in well-defined patterns will be developed. Sophisticated methods will be used to characterise the films produced in these ways, in order to provide the information necessary to refine procedures and design new molecules suitable for advanced applications. Expected outcomes are new methods and architectures that can ultimately yield devices that act at the molecular level.Read moreRead less
Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be disc ....Tailoring the microwave dielectric properties of promising electroceramics for use in wireless telecommunication components and devices. This project aims to develop and tailor the microwave dielectric properties of promising electroceramic materials specifically targeting next generation wireless telecommunications applications. The partnership between the ANU and the Australian company Microwave and Materials Designs has the potential to enable new microwave electroceramic materials to be discovered and then incorporated into new microwave components and/or devices developed in response to the requirements of the international wireless telecommunications market. The requested PhD student will gain experience in both the industrial and academic worlds and the skills needed to be part of Australia's high-tech workforce. Read moreRead less