Manipulation of Biological Particles Using Dielectrophoresis. Dielectrophoretic manipulation and separation of particles has numerous biological and medical applications, e.g. identification and characterisation of individual cells, purification of cell subpopulations from mixture suspensions, etc. This research project aims to develop a high-efficiency and low-cost DEP device for bio-particle manipulation. It will contribute significantly to the advancements in the field of biological Micro-Ele ....Manipulation of Biological Particles Using Dielectrophoresis. Dielectrophoretic manipulation and separation of particles has numerous biological and medical applications, e.g. identification and characterisation of individual cells, purification of cell subpopulations from mixture suspensions, etc. This research project aims to develop a high-efficiency and low-cost DEP device for bio-particle manipulation. It will contribute significantly to the advancements in the field of biological Micro-Electrical-Mechanical-Systems (MEMS) and nanotechnology. Industry will benefit from the expertise on micro/nano-structures and micro/nano-manufacturing achieved by this project.Read moreRead less
Transport phenomena in foam fractionation. Foam fractionation has a number of immediate applications in mineral and food processing but its most exciting potential is as low cost alternative for recovering and purifying high value biosurfactants. These are materials used to stabilise interfaces in living systems, and can be used as antibiotics and antiviral agents. The affinity for biosurfactants to collect at an interface suggests that foam fractionation is an ideal process to concentrate valua ....Transport phenomena in foam fractionation. Foam fractionation has a number of immediate applications in mineral and food processing but its most exciting potential is as low cost alternative for recovering and purifying high value biosurfactants. These are materials used to stabilise interfaces in living systems, and can be used as antibiotics and antiviral agents. The affinity for biosurfactants to collect at an interface suggests that foam fractionation is an ideal process to concentrate valuable products. Clearly, a cost-effective and reliable method of enriching streams of biosurfactants will make their use even more attractive and will engender the development of more novel biomaterials, such as pepfactants.Read moreRead less
Microfluidic device for microbial separation and concentration. This project will enhance Australia's capabilities and presence in the rapidly expanding field of chemical and biological analysis systems on a chip. We will develop and build handheld devices for microbial concentration that will facilitate earlier and easier detection of potentially pathogenic organisms in critical situations such as epidemiological crises or forensics. The portability and ease of operation of our integrated micro ....Microfluidic device for microbial separation and concentration. This project will enhance Australia's capabilities and presence in the rapidly expanding field of chemical and biological analysis systems on a chip. We will develop and build handheld devices for microbial concentration that will facilitate earlier and easier detection of potentially pathogenic organisms in critical situations such as epidemiological crises or forensics. The portability and ease of operation of our integrated microfluidic devices and their increased resilience to blockages make them ideal for use in remote areas and non-laboratory settings. Application areas will include disease detection, microbial contamination in food industries and water quality monitoring.Read moreRead less
Rapid CYBERNOSE ® detection of illicit drugs and precursor chemicals. Rapid CYBERNOSE ® detection of illicit drugs and precursor chemicals. This project aims to develop a novel biosensor prototype based on CYBERNOSE® technology to rapidly identify volatile traces of illicit drugs and precursor chemicals in concealed environments. The CYBERNOSE® technology employs sensors using the highly sophisticated and sensitive olfactory receptors of microscopic nematode worms linked to an optoelectronic det ....Rapid CYBERNOSE ® detection of illicit drugs and precursor chemicals. Rapid CYBERNOSE ® detection of illicit drugs and precursor chemicals. This project aims to develop a novel biosensor prototype based on CYBERNOSE® technology to rapidly identify volatile traces of illicit drugs and precursor chemicals in concealed environments. The CYBERNOSE® technology employs sensors using the highly sophisticated and sensitive olfactory receptors of microscopic nematode worms linked to an optoelectronic detector. The need for rapid, non-contact screening devices to detect and identify illicit drugs and precursors entering Australia has never been greater. Law enforcement agencies should directly benefit from the capability to more rapidly screen people and cargo, improving efficiency of illicit drug detection and protection of our borders.Read moreRead less
Underlying mechanisms of e-waste bioleaching and hydropyrolysis. The project will develop a reclamation technology with an ecologically sustainable solution to e-waste management. Focusing on printed circuit boards, we will use our novel bioleaching and hydropyrolysis methods to process e-wastes, recover base and precious metals and reclaim energy. This will create safe working methods, high recycling efficiencies and generation of products from e-wastes.
Miniaturised biosensors with high selectivity . This project aims to develop a technological platform for the fabrication of miniaturised and flexible sensors that enable the quantitative detection of important bioactive compounds such as fatty acids and biogenic amines. By utilising multi-enzymatic reactions in solid phase and engineering task-specific inks, chemiresistive sensors will be printed seamlessly as a whole. The sensors will respond to complex target biomolecules via a series of enzy ....Miniaturised biosensors with high selectivity . This project aims to develop a technological platform for the fabrication of miniaturised and flexible sensors that enable the quantitative detection of important bioactive compounds such as fatty acids and biogenic amines. By utilising multi-enzymatic reactions in solid phase and engineering task-specific inks, chemiresistive sensors will be printed seamlessly as a whole. The sensors will respond to complex target biomolecules via a series of enzymatic reactions through which the analyte will convert to much simpler, reactive and hence measurable molecules. This project will enable to design miniaturised sensors for point-of-care detection of biomolecules that cannot be yet evaluated by the end users.Read moreRead less
Special Research Initiatives - Grant ID: SR0354787
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 biorem ....Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 bioremediation and algal/bacterial systems for the bioremediation of contaminated soils. This will be achieved by applying research on photosynthetic light utilisation efficiency and carbon fixation, chlorophyll fluorescence, biochemistry of secondary metabolites, molecular biology and photobioreactor design and engineering, informed by an understanding of the ecology of these algae.Read moreRead less
Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at ....Efficient Operation of Bioreactors using Nonlinear Dynamical Systems Theory. Current methods of determining optimal operating conditions in bioreactors have recently been shown to be inefficient, resulting in serious omissions of crucial parameter regions. We will use mathematical techniques from dynamical systems theory to establish a general framework by which bioreactor systems can be efficiently and systematically investigated to improve reactor performance. By communicating these results at relevant fora, we will increase the awareness within the Australian and international engineering communities of the advantages of modern mathematical techniques. Although this proposal focuses on bioreactors, the techniques can be easily adapted to improve the performances of other chemical processes.
Read moreRead less
The microbiology and biotechnology of rum production. Rum is an alcoholic beverage produced by microbial fermentation of molasses waste from the sugar industry. The microbial species responsible for the process determine rum flavour and quality by production of specific aroma compounds. The rate and extent of fermentation determine process efficiency. Several yeast and bacterial species contribute to rum fermentation but this ecology is poorly defined. Through a combination of ecological stu ....The microbiology and biotechnology of rum production. Rum is an alcoholic beverage produced by microbial fermentation of molasses waste from the sugar industry. The microbial species responsible for the process determine rum flavour and quality by production of specific aroma compounds. The rate and extent of fermentation determine process efficiency. Several yeast and bacterial species contribute to rum fermentation but this ecology is poorly defined. Through a combination of ecological studies, controlled fermentations and distillation, chemical and sensory analyses, this project will determine the impact of particular microbial species on rum flavour and process efficiency. This information will be used by the industrial partner to enchance product quality and process efficiency.Read moreRead less
Development of mature and intense flavours in low-fat cheeses using micro-encapsulated enzyme technology. Obesity related diseases are escalating in Australia. Consumers, although encouraged to favour low-fat alternatives in their diet to combat obesity, find low-fat alternatives unpalatable and continue to select full-fat alternatives. There is a need to provide consumers with a full-fat flavoured low-fat cheese. The aim of this project is to develop low-fat cheese products with flavours compar ....Development of mature and intense flavours in low-fat cheeses using micro-encapsulated enzyme technology. Obesity related diseases are escalating in Australia. Consumers, although encouraged to favour low-fat alternatives in their diet to combat obesity, find low-fat alternatives unpalatable and continue to select full-fat alternatives. There is a need to provide consumers with a full-fat flavoured low-fat cheese. The aim of this project is to develop low-fat cheese products with flavours comparable to fully ripened, mature, full-fat cheeses using microencapsulation technology. The outcome will be a rise in demand for low-fat cheese products that will reduce dietary fat intake while maintaining the positive nutritional benefits associated with cheese.Read moreRead less