Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883080
Funder
Australian Research Council
Funding Amount
$490,000.00
Summary
Detection of Trace Concentrations of Chemical Contaminants in Urban Water Systems. Water is a critical resource in Australia and as pressures on water resources increase, water recycling is becoming more prevalent. The presence of chemical contaminants such as low concentrations (ng/L) of pharmaceutically active compounds (PhACs), endocrine disrupters (EDCs) and other organic micropollutants in the aquatic environment has received much attention around the world including Australia due to their ....Detection of Trace Concentrations of Chemical Contaminants in Urban Water Systems. Water is a critical resource in Australia and as pressures on water resources increase, water recycling is becoming more prevalent. The presence of chemical contaminants such as low concentrations (ng/L) of pharmaceutically active compounds (PhACs), endocrine disrupters (EDCs) and other organic micropollutants in the aquatic environment has received much attention around the world including Australia due to their potential biological impact in urban water systems. The proposed equipment aims to establish analytical techniques and instrumental capacity for the selective analysis of chemical contaminants in order to improve our understanding of the fate of these compounds through different urban water systems.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102503
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Circulating tumor cell isolation and detection: an integrated microfluidic capture device based on alternating current (AC) electrohydrodynamics. The detection of circulating tumor cells in clinical samples plays a critical role in cancer diagnosis and management. This project aims to develop microfluidic technology by incorporating AC electric field-induced vortices with three-dimensional microstructured electrodes that will advance our ability to analyse rare cells and proteins in clinical sam ....Circulating tumor cell isolation and detection: an integrated microfluidic capture device based on alternating current (AC) electrohydrodynamics. The detection of circulating tumor cells in clinical samples plays a critical role in cancer diagnosis and management. This project aims to develop microfluidic technology by incorporating AC electric field-induced vortices with three-dimensional microstructured electrodes that will advance our ability to analyse rare cells and proteins in clinical samples.Read moreRead less
Tuneable “Nano-Shearing”: An Innovative Mechanism for the Accurate and Specific Capture of Cells and Molecules. Recent investigations have discovered a tuneable electro-hydrodynamic force which drives lateral fluid motion within a few nanometers of an electrode surface. Because the magnitude of this fluid shear force can be tuned externally (for example, via the application of an AC electric field), it provides a new capability to physically displace weakly (non-specifically) bound cellular and ....Tuneable “Nano-Shearing”: An Innovative Mechanism for the Accurate and Specific Capture of Cells and Molecules. Recent investigations have discovered a tuneable electro-hydrodynamic force which drives lateral fluid motion within a few nanometers of an electrode surface. Because the magnitude of this fluid shear force can be tuned externally (for example, via the application of an AC electric field), it provides a new capability to physically displace weakly (non-specifically) bound cellular and molecular analytes. By performing research to further understand and develop this tuneable effect, this project aims to build and test a new platform technology to enable highly efficient capture and specific detection of low concentration pathogenic molecules and circulating tumour cells (CTCs).Read moreRead less
Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. ....Microchip Impedance Biosensor for Biomedical Diagnostics. This research proposal uses an innovative engineering approach based on novel nanomaterials with the aim of developing a new and generic biosensing technology with the potential to be widely applied in many areas including medical diagnostics, environmental control, industry and biosecurity. The outcomes from this project will benefit Australia by contributing through the development of novel materials, new technologies and new devices. The development of technological innovations based on fabricated nanomaterials, will also enhance capacity in frontier technology such as nanotechnology, and build Australia’s strength in using new biosensing technologies.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100035
Funder
Australian Research Council
Funding Amount
$4,958,927.00
Summary
ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, ....ARC Training Centre for Hyphenated Analytical Separation Technologies . The toughest analytical science challenges typically require advanced analytical technologies to acquire the desired solutions. In the field of separation science this inevitably involves hyphenated separation technologies, specifically the combination of chromatography and mass spectrometry. Advancing this technology to its full capability requires the collaborative strength of academic, industry and end-user partnerships, providing the materials and inspiration for young researchers to apply novel hyphenated methods to complex environmental and industrial systems. This Centre will deliver fundamental developments in hyphenated technologies, new analytical capability, and applied outcomes across multiple end-user groups and interests. Read moreRead less
Imaging the world of miniature venomous arthropods. Venomous arthropods produce a myriad of biologically active peptides, with many having potential as pharmacological tools, bioinsecticides and pharmaceuticals. Most studies to date have focussed on large arthropods; smaller species remain neglected due to the difficulties of venom collection. This project seeks to further advance the pioneering imaging mass spectrometry approaches the project team developed for imaging toxins in the venom gland ....Imaging the world of miniature venomous arthropods. Venomous arthropods produce a myriad of biologically active peptides, with many having potential as pharmacological tools, bioinsecticides and pharmaceuticals. Most studies to date have focussed on large arthropods; smaller species remain neglected due to the difficulties of venom collection. This project seeks to further advance the pioneering imaging mass spectrometry approaches the project team developed for imaging toxins in the venom glands of spiders and centipedes. By combining high-resolution matrix-assisted laser desorption ionisation imaging data with histological and transcriptomic information the project aims to provide the first detailed insights into the neglected world of miniature arthropod venoms. The approaches developed by this project aim to have wide application in the field of biology.Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less
Incorporating Design Management Culture within the Total Project Management Process: a Socio-technical Approach. New project delivery methods (e.g. design & construct; alliance contracting) in major commercial and infrastructure projects have the potential to dramatically increase the value added to clients and the wider community.
However to realise this potential, we need to better understand those socio-technical factors that foster an effective design management culture within tradition ....Incorporating Design Management Culture within the Total Project Management Process: a Socio-technical Approach. New project delivery methods (e.g. design & construct; alliance contracting) in major commercial and infrastructure projects have the potential to dramatically increase the value added to clients and the wider community.
However to realise this potential, we need to better understand those socio-technical factors that foster an effective design management culture within traditional construction companies, especially their knowledge sharing culture.
This project will develop and test an innovative research methodology that blends approaches from the social sciences and engineering. The findings regarding design management will have wide applicability to industry and cover civil, building, mining and process engineering projects, each of which has its own culture.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100115
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploi ....High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploit interfacial phenomena and to tailor processing-microstructure-composition correlations, so as to design new materials with the best performance possible. Probes with unique capabilities will measure surface morphology, optical properties, elemental composition and crystallographic phase.The facility will be the first in Australia to offer a comprehensive study of structure and properties at high temperature.Read moreRead less
Mining venture risk: novel econometric methods to integrate joint financial and geological uncertainty into dynamic risk forecasting measures. The mining industry is nationally important: it contributed $33,927M to Australia's GDP in 2002-3. This project's outcomes - sophisticated statistical and econometric tools - will significantly improve capability for forecasting overall risk to mining projects requiring vast upfront, irreversible investments, and contribute to its efficiency and internati ....Mining venture risk: novel econometric methods to integrate joint financial and geological uncertainty into dynamic risk forecasting measures. The mining industry is nationally important: it contributed $33,927M to Australia's GDP in 2002-3. This project's outcomes - sophisticated statistical and econometric tools - will significantly improve capability for forecasting overall risk to mining projects requiring vast upfront, irreversible investments, and contribute to its efficiency and international competitiveness. Innovative methods driven by data from complex financial and geological systems will integrate price volatility risk and orebody uncertainty in a real options framework, providing holistic, rigorous measurement of mining venture risk. Xstrata Queensland Ltd will strongly support and participate in research training of an identified candidate to deliver discoveries to the wider industry.Read moreRead less