Periodic nano-ratchets: a new paradigm for biomolecule separation. This project proposes the theoretical and experimental study of a new separation principle. The platform technologies developed from this research will see wide ranging applications. They will reveal new insights into fundamental phenomena of membranes and separation processes underpinning development of new generation of separation technologies. New membranes and microchip separation devices which can be applied to genomic, prot ....Periodic nano-ratchets: a new paradigm for biomolecule separation. This project proposes the theoretical and experimental study of a new separation principle. The platform technologies developed from this research will see wide ranging applications. They will reveal new insights into fundamental phenomena of membranes and separation processes underpinning development of new generation of separation technologies. New membranes and microchip separation devices which can be applied to genomic, proteomic, forensic and a range medical, biotechnological and analytical applications will be readily achievable. This is an international and interdisciplinary research project and its outcomes will enhance Australia's ability in frontier technologies, advanced materials.Read moreRead less
Novel approach to study mechanisms of Na+ transport in plants using Lab on a Chip technology. A Lab on a Chip for sodium ion measurements in plants is proposed, offering a long overdue solution to the lack of appropriate techniques to study the mechanisms of sodium iron uptake, transport and compartmentation. Sodium ion transport is a key determinant of salt tolerance, but a good understanding of its transport mechanisms is lacking since no appropriate measurement tools are available. Using the ....Novel approach to study mechanisms of Na+ transport in plants using Lab on a Chip technology. A Lab on a Chip for sodium ion measurements in plants is proposed, offering a long overdue solution to the lack of appropriate techniques to study the mechanisms of sodium iron uptake, transport and compartmentation. Sodium ion transport is a key determinant of salt tolerance, but a good understanding of its transport mechanisms is lacking since no appropriate measurement tools are available. Using the system proposed here, sodium ion is separated from interfering ions, allowing fast and selective measurements. A series of ground breaking studies towards sodium ion uptake, transport and compartmentation in plants will be conducted using this Lab on a Chip.Read moreRead less
Disposable microdevices for fast ion analysis. The design and fabrication of a microdevice for ion chromatography will introduce Australia to the field of miniaturised total analytical systems (µTAS). The availability of infrastructure, technology and experience in the µTAS area will provide the foundation for specialised commercialisation of sophisticated, chip-based analytical instruments. These instruments have important applications in forensic, clinical and environmental chemistry.
Development of Advanced Detection Systems for Accelerator Mass Spectrometry. This project aims to expand significantly the range of isotopes available for accelerator mass spectrometry at the Australian National University to include the ability to detect manganese-53, nickel-59 and uranium-236 to ultra-sensitive concentrations. To achieve this, my extensive experience in fundamental nuclear physics will be exploited to develop a gas-filled magnet for the detection of mangnese-53 and nickel-59, ....Development of Advanced Detection Systems for Accelerator Mass Spectrometry. This project aims to expand significantly the range of isotopes available for accelerator mass spectrometry at the Australian National University to include the ability to detect manganese-53, nickel-59 and uranium-236 to ultra-sensitive concentrations. To achieve this, my extensive experience in fundamental nuclear physics will be exploited to develop a gas-filled magnet for the detection of mangnese-53 and nickel-59, and a time-of-flight detector to detect uranium-236. This project has applications in the topical areas of climate change and nuclear safeguards, as well as applications in the earth sciences and the management of nuclear waste.Read moreRead less
Indium arsenic antimony (InAsSb) Quantum Dots for Mid-Infrared Lasers. This proposal will open a new area of research for mid-infrared laser devices. Any achievement from this project will benefit various academic and industrial communities, such as national security, environmental monitoring and spectroscopy. The outcomes of this research could create a new generation of high-performance mid-infrared lasers and put Australian researchers in the forefront of the development in this field.
Marine oil seeps and airborne particulates characterisation for organic compositional fingerprinting by using novel gas chromatographic technologies. Comprehensive two-dimensional gas chromatography (GCxGC) is a powerful new tool for studying complex organic materials. The technique provides a highly sensitive method of fingerprinting not only the composition of the material but also its environmental history and behaviour. In this project the technique will be applied to a range of petroleum- ....Marine oil seeps and airborne particulates characterisation for organic compositional fingerprinting by using novel gas chromatographic technologies. Comprehensive two-dimensional gas chromatography (GCxGC) is a powerful new tool for studying complex organic materials. The technique provides a highly sensitive method of fingerprinting not only the composition of the material but also its environmental history and behaviour. In this project the technique will be applied to a range of petroleum-related organic samples, including oil seeps from the ocean floor, and airborne particulates contributing to air pollution. The research will lead to a better understanding of geochemistry of petroleum-related materials and their potential impact on the environment and on public health.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237784
Funder
Australian Research Council
Funding Amount
$707,000.00
Summary
Hyphenated Separations/Mass Spectrometry Technology for Protein and Natural Product Characterisation. This proposal consolidates the 3 institutions' collaboration on the ACROSS (Australian Centre for Research on Separation Science) initiative, providing fundamental technology for chemical structural analysis of complex samples involving high resolution protein and natural product characterisation. Requested equipment supports complete characterisation of important novel target molecules. GCxGC-T ....Hyphenated Separations/Mass Spectrometry Technology for Protein and Natural Product Characterisation. This proposal consolidates the 3 institutions' collaboration on the ACROSS (Australian Centre for Research on Separation Science) initiative, providing fundamental technology for chemical structural analysis of complex samples involving high resolution protein and natural product characterisation. Requested equipment supports complete characterisation of important novel target molecules. GCxGC-TOFMS technology will validate our newly patented multidimensional separation techniques. Q-TOF-TOFMS technology, novel patented protein prefractionation approaches, and sample handling with high resolution characterisation / identification of new target proteins allows advanced proteomics developments. Proteomics depends critically upon sophisticated MS techniques. These technologies will: ·enhance the capabilities and expertise in these sciences in the SE Australian area; ·ensure the ACROSS initiative achieves internationally competitive research capabilities; ·provide commercial endpoints in fields associated with analysis of proteins, essential oils and other natural (bio)substances.Read moreRead less
Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will signific ....Vibration Isolation Technology and Instrumentaion for Geophysical Surveys. Many geophysical exploration instruments are limited in sensitivity by vibration induced noise. New techniques of vibration isolation have been shown to eliminate vibration induced noise in a vibrating wire magnetic gradiometer. This project will create fully integrated sensor ?isolation packages for airborne and underwater applications, both for gradiometers and for ground penetrating radars. The project will significantly benefit the mineral exploration industry as well as underwater detection of cables and ship wrecks.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989492
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Dynamic Texture Measurement Facility. A texture goniometer is an advanced tool for texture characterisation of steels, light alloys, nanomaterials, superconductors and minerals. The ability to conduct dynamic texture measurements will significantly enhance the effectiveness of four material-based research institutes at the University of Wollongong and at Deakin University, as well as collaborative research with BlueScope Steel. The research is directly aligned to the National Research Priority o ....Dynamic Texture Measurement Facility. A texture goniometer is an advanced tool for texture characterisation of steels, light alloys, nanomaterials, superconductors and minerals. The ability to conduct dynamic texture measurements will significantly enhance the effectiveness of four material-based research institutes at the University of Wollongong and at Deakin University, as well as collaborative research with BlueScope Steel. The research is directly aligned to the National Research Priority of Frontier Technologies for Building and Transforming Australian Industry. The equipment will provide a valuable resource for industries in the Illawarra region of NSW and in regional South-West Victoria.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989541
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will c ....High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will contribute to the priority area 'Promoting and Maintaining Good Health'. In addition, the new equipment will extend capabilities and postgraduate training in chemistry, nanotechnology, and biomedicine (the priority area of 'Frontier Technologies for Building and Transforming Australian Industries').Read moreRead less