Randomised Double-blind Controlled Trial Of Oxygen Versus Air To Palliate Intractable End-of-life Dyspnoea When Pa02 >55
Funder
National Health and Medical Research Council
Funding Amount
$463,318.00
Summary
Shortness of breath at the end-of-life is one of the most feared symptoms. Unlike most other symptoms, it worsens as death approaches. Despite the fact that more than 50,000 Australian will die an expected death in the next year, of whom the majority will have breathlessness toward the end-of-life, we know little about how best to treat this symptom. Oxygen is frequently introduced but we have not identified whether it is more effective than medical air, and, if it is more effective, which patie ....Shortness of breath at the end-of-life is one of the most feared symptoms. Unlike most other symptoms, it worsens as death approaches. Despite the fact that more than 50,000 Australian will die an expected death in the next year, of whom the majority will have breathlessness toward the end-of-life, we know little about how best to treat this symptom. Oxygen is frequently introduced but we have not identified whether it is more effective than medical air, and, if it is more effective, which patients would most benefit from it. Because of this lack of evidence, oxygen is only funded in Australia in community settings for people who have severely low oxygen levels in their blood. Palliative oxygen is provided on a compassionate basis at times but this is on an ad hoc basis and does not ensure equitable access for people at the end of life who experience shortness of breath. This multi-centre study will compare oxygen and air, with neither the participant nor caring clinicians knowing which treatment they will receive. After careful explanation, volunteers who agree to participate will be asked to use the oxygen machine for at least 15 hours each day for 7 days and fill out a diary twice each day. Five centres across Australia are planning to enroll 240 participants in this study. Outcomes will include whether the sensation of breathlessness has improved, the overall quality of life while being treated, the ability to perform activities of daily living and any side effects experienced. This study is eagerly awaited by clinicians and health planners not only in Australia but in North America and Europe. This study will provide data in a long-standing international debate about the role of oxygen in people with relatively normal levels of oxygen in their blood who suffer from shortness of breath at the end-of-life.Read moreRead less
Multi-centre RDBC Trial Of Oxygen Vs Air For Relief Of Breathlessness In Terminally-ill Patients With Intractable Dyspno
Funder
National Health and Medical Research Council
Funding Amount
$149,701.00
Summary
This study will compare the effects of oxygen and air in the relief of breathlessness in patients at the end of life who do not currently qualify for home oxygen. This landmark study will provide accurate information about any benefits that oxygen offers for breathlessness in this setting. This international multi-site study will ask 226 people to participate using either oxygen or air for 7 days while keeping a diary. We will measure breathlessness, quality of life, anxiety and side effects exp ....This study will compare the effects of oxygen and air in the relief of breathlessness in patients at the end of life who do not currently qualify for home oxygen. This landmark study will provide accurate information about any benefits that oxygen offers for breathlessness in this setting. This international multi-site study will ask 226 people to participate using either oxygen or air for 7 days while keeping a diary. We will measure breathlessness, quality of life, anxiety and side effects experienced.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560930
Funder
Australian Research Council
Funding Amount
$167,777.00
Summary
Airborne laser scanning for advanced environmental monitoring. This proposal seeks to enhance the national capability for airborne remote sensing of key environmental variables through the acquisition of an airborne laser scanner and inertial navigation system. Many environmental science studies, such as hydrology, soil moisture scaling and salinity, can be significantly enhanced by airborne laser scanning, through the creation of high precision, high resolution digital terrain models. Airborne ....Airborne laser scanning for advanced environmental monitoring. This proposal seeks to enhance the national capability for airborne remote sensing of key environmental variables through the acquisition of an airborne laser scanner and inertial navigation system. Many environmental science studies, such as hydrology, soil moisture scaling and salinity, can be significantly enhanced by airborne laser scanning, through the creation of high precision, high resolution digital terrain models. Airborne laser scanning can also measure three dimensional vegetation canopy structure, a useful indicator of biomass, carbon storage and vegetation health. This infrastructure will provide Australian researchers with a unique arsenal of remote sensing tools for advanced yet affordable environmental research studies.Read moreRead less
Unlocking the Grid: the future of the electricity distribution network. This project applies to the National Research Priority of an environmentally sustainable Australia. A critical challenge for the development of power systems will be to transform them from their current dependence on conventional centralised generation to a situation where more diversified, more volatile and less controllable generation sources contribute a significant percentage of the energy. Coupled with this is a change ....Unlocking the Grid: the future of the electricity distribution network. This project applies to the National Research Priority of an environmentally sustainable Australia. A critical challenge for the development of power systems will be to transform them from their current dependence on conventional centralised generation to a situation where more diversified, more volatile and less controllable generation sources contribute a significant percentage of the energy. Coupled with this is a change in demand patterns due to both demographic and socio-economic variables as well as climate change. Careful analysis is required in the design of the future grid architecture to ensure the security of supply.Read moreRead less
Spatial and temporal monitoring of soil erosion risk with satellite imagery. This project is directed towards Sustainable farm practices, one of the national priorities in the Caring for Our Country program. The satellite image-based monitoring system will provide new information about the changing distribution of erosion risk in seasonal cropping systems, and identify areas where agricultural practices significantly influence this risk. The research will allow landholders, regional, state and n ....Spatial and temporal monitoring of soil erosion risk with satellite imagery. This project is directed towards Sustainable farm practices, one of the national priorities in the Caring for Our Country program. The satellite image-based monitoring system will provide new information about the changing distribution of erosion risk in seasonal cropping systems, and identify areas where agricultural practices significantly influence this risk. The research will allow landholders, regional, state and national authorities to better target effort towards sustainable land management, and improve monitoring and reporting of land condition across broad agricultural regions. Dynamic monitoring of erosion risk will also track landscape conditions and farmer responses to changing climate.Read moreRead less
Airborne spatial tracking to save endangered species. Airborne spatial tracking to save endangered species. This project aims to develop an automated and distributed spatial tracking approach using low cost Unmanned Aerial Vehicles (UAVs) to locate and study endangered wildlife. Understanding animal behaviour and habits with granular spatial data is essential to develop effective monitoring and conservation strategies. Spatial tracking of radio collared wildlife using radio telemetry is a critic ....Airborne spatial tracking to save endangered species. Airborne spatial tracking to save endangered species. This project aims to develop an automated and distributed spatial tracking approach using low cost Unmanned Aerial Vehicles (UAVs) to locate and study endangered wildlife. Understanding animal behaviour and habits with granular spatial data is essential to develop effective monitoring and conservation strategies. Spatial tracking of radio collared wildlife using radio telemetry is a critical but costly tool for acquiring this data. This project anticipates that airborne spatial tracking using intelligent spatial tracking algorithms on board low cost UAV teams will allow more precise understanding of wildlife for evidence-based conservation and management in a changing global climate.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100118
Funder
Australian Research Council
Funding Amount
$159,450.00
Summary
Sensor calibration facility for spectral and thermal remote sensing. This project aims to establish a calibration facility for the radiometric and spectral correction of hyperspectral and thermal sensors for ultrahigh-resolution remote sensing. Sensor calibration and characterisation is critical to the accuracy of hyperspectral and thermal data products, however, there is no central facility in Australia for this purpose. This project will provide significant benefits, such as growing our capaci ....Sensor calibration facility for spectral and thermal remote sensing. This project aims to establish a calibration facility for the radiometric and spectral correction of hyperspectral and thermal sensors for ultrahigh-resolution remote sensing. Sensor calibration and characterisation is critical to the accuracy of hyperspectral and thermal data products, however, there is no central facility in Australia for this purpose. This project will provide significant benefits, such as growing our capacity in ultrahigh-resolution remote sensing for ecosystem science, biosecurity, and disaster response.Read moreRead less
Photogrammetric Reconstruction for Underwater Virtual Heritage Experiences. This project aims to enable significant underwater cultural heritage sites such as shipwrecks to be recreated in immersive underwater virtual heritage experiences. Photogrammetric 3D reconstruction techniques will be used to generate complex digital 3D models of shipwreck sites from hundreds of thousands of underwater images. This will allow vivid experiences to be created which explain the stories of these wrecks. The p ....Photogrammetric Reconstruction for Underwater Virtual Heritage Experiences. This project aims to enable significant underwater cultural heritage sites such as shipwrecks to be recreated in immersive underwater virtual heritage experiences. Photogrammetric 3D reconstruction techniques will be used to generate complex digital 3D models of shipwreck sites from hundreds of thousands of underwater images. This will allow vivid experiences to be created which explain the stories of these wrecks. The project will conduct audience engagement studies to recommend the most appropriate methods to implement underwater virtual heritage experiences for Australian audiences. The sites which will be used as test datasets are some of the most significant Australian shipwreck sites, including HMAS Sydney (II) and HMAS AE1.Read moreRead less