It has become increasingly evident that damage to the genetic material in cells (DNA) is a fundamental initiating cause of cancer and accelerated ageing. Furthermore it has been shown recently that moderate deficiencies of certain vitamins and minerals can cause damage to DNA at a level that is observed for carcinogenic doses of radiation and toxic chemicals. In addition studies have shown that supplementation with certain vitamins resulted in a reduction of damage to DNA. The aims of this resea ....It has become increasingly evident that damage to the genetic material in cells (DNA) is a fundamental initiating cause of cancer and accelerated ageing. Furthermore it has been shown recently that moderate deficiencies of certain vitamins and minerals can cause damage to DNA at a level that is observed for carcinogenic doses of radiation and toxic chemicals. In addition studies have shown that supplementation with certain vitamins resulted in a reduction of damage to DNA. The aims of this research is to determine whether daily intake of a pill containing certain vitamins and minerals causes a reduction in DNA damage in blood cells. The expected ultimate outcome is a cancer prevention strategy based on reducing the risk of damage to DNA.Read moreRead less
Improving Evidence-based Treatment Of Latent Tuberculosis Infection In Public-hospital Based Chest Clinics
Funder
National Health and Medical Research Council
Funding Amount
$176,250.00
Summary
The aim of this project is to implement an electronic decision support (EDS) tool for preventive tuberculosis treatment into clinical practice. Information needs of patients and physicians as well as practical concerns regarding the use of the EDS will be evaluated before performing pilot testing and evaluating the impact of the EDS tool on simulated doctor-patient interactions and clinical workflow.
Understanding Tendon Response to Sport and Exercise: Implications for Optimising Training, Injury Prevention and Accelerated Rehabilitation. This research will use frontier technologies to establish the effect of physical activity on tendon adaptation and injury. It will address National Research Priorities and lead to contemporary evidence-based physical activity practices to optimise health and fitness, prevent injury, and expedite rehabilitation after injury. Given the significant national in ....Understanding Tendon Response to Sport and Exercise: Implications for Optimising Training, Injury Prevention and Accelerated Rehabilitation. This research will use frontier technologies to establish the effect of physical activity on tendon adaptation and injury. It will address National Research Priorities and lead to contemporary evidence-based physical activity practices to optimise health and fitness, prevent injury, and expedite rehabilitation after injury. Given the significant national investment in sport, the rise in obesity, and the immense cost of sedentary behaviour and sport-related injuries, this research will have applications for enhancing physical activity recommendations that maintain health for all Australians. It will enhance Australia's leading position in international sport and sport science research and have beneficial applications for occupational health.Read moreRead less
Citizen engagement: Listening to citizens' views about Australia's health system and prevention. This project will yield new and important perspectives from citizens on preventive health and health promotion, which can be used to develop better targeted and more effective prevention and promotion policies and strategies. Citizens views will be investigated in relation to vexed issues such as: new approaches to financing and program delivery, reorienting the health insurance sector, reorienting ....Citizen engagement: Listening to citizens' views about Australia's health system and prevention. This project will yield new and important perspectives from citizens on preventive health and health promotion, which can be used to develop better targeted and more effective prevention and promotion policies and strategies. Citizens views will be investigated in relation to vexed issues such as: new approaches to financing and program delivery, reorienting the health insurance sector, reorienting the health system to focus more on prevention and health promotion, improving current approaches of consumer participation in prevention and chronic disease management, tackling broader issues in public policy trade-offs between health and non-health, diversifying workforce roles and involving health professionals in prevention and promotion.Read moreRead less
The effect of physical activity and a structured exercise program on the psychological and physical development of Australian primary school children. This study will explore the effects of early childhood physical activity on development. Our study will assess quantitatively the beneficial effects of exercise on personal and physical growth in young children in a non-intimidating way using a specifically designed exercise program.
A prospective investigation of self-injury, suicidal ideation and psychological distress in Australian secondary school students. Suicide prevention has been a national priority for the past 10 years. Self-injury is a predictor of suicide, results in considerable distress for family and friends and is associated with significant health care expenditure. In addition the known correlates of self-injury, such as depression and substance use, also pose significant burden to society and are themselve ....A prospective investigation of self-injury, suicidal ideation and psychological distress in Australian secondary school students. Suicide prevention has been a national priority for the past 10 years. Self-injury is a predictor of suicide, results in considerable distress for family and friends and is associated with significant health care expenditure. In addition the known correlates of self-injury, such as depression and substance use, also pose significant burden to society and are themselves predictors of suicide. Understanding the nature and extent of self-injury in Australian adolescents, and the causal relationships between self-injury, suicidal ideation and psychological distress, will improve the care given to those who self-injure, improve their well-being, decrease their chances of further self-injury, and decrease the chance they will die by suicide.Read moreRead less
Do perceptions of morality of alcohol, tobacco & cannabis use influence uptake in high school? In Australia, the cost of drug use was estimated at $34.4 billion in 1998-89. Preventing or delaying alcohol, tobacco and illicit drug use among adolescents is a way of reducing substance use among adults, and therefore, reduces the health, social and economic costs associated with substance use. This study will assess the protective/vulnerability effect of a range of variables on youth substance use i ....Do perceptions of morality of alcohol, tobacco & cannabis use influence uptake in high school? In Australia, the cost of drug use was estimated at $34.4 billion in 1998-89. Preventing or delaying alcohol, tobacco and illicit drug use among adolescents is a way of reducing substance use among adults, and therefore, reduces the health, social and economic costs associated with substance use. This study will assess the protective/vulnerability effect of a range of variables on youth substance use including morality and legitimacy concepts. These data will guide the development of curriculum components to enhance the effect of school-based interventions with respect to substance use, and provide practical recommendations for community interventions targeted at substance use.Read moreRead less
What works best for youth smoking prevention messages? In Australia, tobacco smoking is the leading cause of preventable death and disease, resulting in over 19,000 deaths annually. The morbidity and mortality associated with smoking costs the community over $21 billion a year. People who start smoking when they are young are more likely to smoke heavily as adults, to become more dependent on nicotine and to be at increased risk of smoking-related illness or death. This research study will provi ....What works best for youth smoking prevention messages? In Australia, tobacco smoking is the leading cause of preventable death and disease, resulting in over 19,000 deaths annually. The morbidity and mortality associated with smoking costs the community over $21 billion a year. People who start smoking when they are young are more likely to smoke heavily as adults, to become more dependent on nicotine and to be at increased risk of smoking-related illness or death. This research study will provide practical recommendations for future tobacco control television advertising targeted at youth in terms of the elements featured in tobacco control advertisements that increase advertising effectiveness. Read moreRead less
Long term economic impacts of disease on older workers to 2030: Costs to government and individuals and opportunities for intervention. This project will fill substantial gaps in Australian evidence about the health conditions of the future that will keep older workers out of the labour market and diminish their own immediate and long-term livings standards, thereby reducing funds available to government. We will address one of the most significant issues resulting from the fundamental changes t ....Long term economic impacts of disease on older workers to 2030: Costs to government and individuals and opportunities for intervention. This project will fill substantial gaps in Australian evidence about the health conditions of the future that will keep older workers out of the labour market and diminish their own immediate and long-term livings standards, thereby reducing funds available to government. We will address one of the most significant issues resulting from the fundamental changes to the demography of the Australian labour market and one that is regularly raised by the government following the release of the 2002 and 2007 Intergenerational Reports. This project will also examine the interventions that would improve the health of older workers and increase labour force participation over the long term.Read moreRead less