The Fish Oil Youth Depression Study: A Randomised, Double Blind, Placebo-controlled Treatment Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,193,322.00
Summary
Long-chain omega-3 fatty acids (‘fish oil’) can reduce symptoms of depression. This, and the fact that they do not cause major side effects and are considered health beneficial, makes them an ideal candidate for early and preventive treatment. Through a controlled trial in tandem with a comprehensive basic research program, we aim to establish long-chain omega-3 fatty acids as first-line treatment for indicated prevention of severe mood disorders and as an alternative to antidepressant medicatio ....Long-chain omega-3 fatty acids (‘fish oil’) can reduce symptoms of depression. This, and the fact that they do not cause major side effects and are considered health beneficial, makes them an ideal candidate for early and preventive treatment. Through a controlled trial in tandem with a comprehensive basic research program, we aim to establish long-chain omega-3 fatty acids as first-line treatment for indicated prevention of severe mood disorders and as an alternative to antidepressant medication in adolescents.Read moreRead less
A Multi-faceted Intervention To Enhance Cognition In Older People At Risk Of Cognitive Decline
Funder
National Health and Medical Research Council
Funding Amount
$600,224.00
Summary
There is an urgent need to investigate interventions which could reduce the number of people living with dementia in the future. This research aims to improve cognition in older people, experiencing early signs of memory decline, using a multi-modal exercise program combined with dietary supplements. Findings from this research will contribute to primary and secondary dementia prevention approaches.
Neuroprotective Functions Of Autophagy Regulators In Alzheimer's Disease
Funder
National Health and Medical Research Council
Funding Amount
$434,644.00
Summary
The accumulation of the beta amyloid protein has a central role in AD and enhancing its removal improves memory loss in animal AD models. This project builds on my recent finding of regulators of a cell housekeeping system, “autophagy” which accelerate removal of beta amyloid in cells. This study will advance knowledge into the protective functions of the autophagy regulators in reducing AD symptoms. Findings from this work might provide the basis for developing effective anti-AD therapeutics.