Elucidating The In Vivo Role Of The Pro-survival Gene Mcl-1 In Mammary Gland Development And Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$664,691.00
Summary
Breast cancer strikes one in 8 women by age 85 and is a major cause of morbidity and mortality. Despite recent improvements, the immense breast cancer burden demands new strategies that will radically improve patient outcomes. This project will address a hallmark of cancer: evasion of apoptosis. Understanding the molecular events that promote tumour survival and resistance to therapy represents a key area in cancer biology that has yet to be properly applied to breast cancer.