Does climatic thermal variability matter? This project aims to research how annual and daily variability in temperature effects the distribution of species, their tolerance to temperature, their dispersal ability and genetic structuring. Expected outcomes include more accurate assessment of the ecological risk of climate change, which is expected to result in altered average temperatures and temperature variability. Such assessments will result in better management of species and ecosystems faci ....Does climatic thermal variability matter? This project aims to research how annual and daily variability in temperature effects the distribution of species, their tolerance to temperature, their dispersal ability and genetic structuring. Expected outcomes include more accurate assessment of the ecological risk of climate change, which is expected to result in altered average temperatures and temperature variability. Such assessments will result in better management of species and ecosystems facing threats from climate change.Read moreRead less
Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be rea ....Assessing gene function in the developing brain using zebrafish as a model system. As the average life expectancy in western countries increases there is an increasing incidence of mental health problems in the general population. Therapeutic approaches to Alzhemier's and Parkinson's disease as well as to brain injury arising from stroke rely on a thorough understanding of the molecular and physiological mechanisms of normal growth of this tissue. These are the very processes that need to be reactivated in these diseases for recovery of function. This project seeks to understand normal development of the brain and in doing so it will expose novel targets for therapy in the aged. Read moreRead less
Making Australia internationally competitive: driving educational attainment by academic motivation, self-concept, engagement and aspirations. This project will extend and test predictions from motivation theory about educational choice and attainment, using multiple large national/international databases and new statistical models. This will result in better strategies to meet government targets of increasing tertiary enrolments, particularly for disadvantaged students.
Genome-level insight into the dynamics of a model coral microbiome. The aim of the project is to examine structural and functional microbiome dynamics in an ecologically important coral on the Great Barrier Reef along a natural temperature gradient. Microorganisms form an intimate symbiotic relationship with corals and are critical to their health. However, the microbiome can be disrupted by environmental perturbations, including higher-than-normal ocean temperatures, leaving the coral susceptib ....Genome-level insight into the dynamics of a model coral microbiome. The aim of the project is to examine structural and functional microbiome dynamics in an ecologically important coral on the Great Barrier Reef along a natural temperature gradient. Microorganisms form an intimate symbiotic relationship with corals and are critical to their health. However, the microbiome can be disrupted by environmental perturbations, including higher-than-normal ocean temperatures, leaving the coral susceptible to disease and bleaching. Currently, our understanding of how the microbiome composition and metabolic function change in response to seasonal temperature variation and disease is limited. This project is designed to provide insight into the role the microbiome plays in maintaining coral health and may aid in the long-term preservation of the reefs.Read moreRead less
Development of Advanced Wear Debris Analysis Techniques for Osteoarthritis Study. Wear and tear of joints is the common cause of osteoarthritis, costing $19.25 billion/year. With this cost on the increase, and no cure to date, comes a need to develop effective methods for its diagnosis. This study will provide new knowledge on osteoarthritis progression by allowing strategic use of national health resources. A fuzzy expert system, to be developed utilising the diagnostic/prognostic techniques of ....Development of Advanced Wear Debris Analysis Techniques for Osteoarthritis Study. Wear and tear of joints is the common cause of osteoarthritis, costing $19.25 billion/year. With this cost on the increase, and no cure to date, comes a need to develop effective methods for its diagnosis. This study will provide new knowledge on osteoarthritis progression by allowing strategic use of national health resources. A fuzzy expert system, to be developed utilising the diagnostic/prognostic techniques of this study will significantly reduce cost and time. The project will contribute to the National Strategy by helping older Australians; the major group of osteoarthritis sufferers, to retain their health, independence and productivity.Read moreRead less
Episodic foresight and ageing. Episodic foresight refers to the capacity to imagine future events, and consequently often involves the prediction of future needs based on hypothesised possible outcomes. It is therefore unsurprising that episodic foresight has been consistently linked to independent living and many functional behaviours. The aim of the project is to test the hypothesis that psychological changes brought about by ageing decrease the likelihood of acting prudently with the future i ....Episodic foresight and ageing. Episodic foresight refers to the capacity to imagine future events, and consequently often involves the prediction of future needs based on hypothesised possible outcomes. It is therefore unsurprising that episodic foresight has been consistently linked to independent living and many functional behaviours. The aim of the project is to test the hypothesis that psychological changes brought about by ageing decrease the likelihood of acting prudently with the future in mind. By advancing conceptual understanding of how, and under what circumstances, episodic foresight is affected in late adulthood, the proposed research has important implications for finding ways to help older adults maintain a productive and independent life. Read moreRead less
Ageing, trust, and financial exploitation: social, emotional and cognitive mechanisms. This project aims to understand how age-related differences in the processing of social and emotional information contribute to the exploitation of older adults' trust. This research will examine deception detection during financial negotiations and provide new strategies for ensuring the financial independence and well-being of older Australians.
Sociophysical Interactions: understanding the role of social and tangible technologies in maintaining good habits into old age. How can technology help us 'age well'? The project will study, design and evaluate novel information systems that integrate and support social engagement and physical activity in order to build foundational knowledge about these technologies and maintain the opportunities for social engagement and physical activity in our ageing population.
Genetics of longevity and the delay of post-reproductive senescence. Ageing of the population in the coming decades will cause an increasing health care burden. Diseases of ageing such as Alzheimer's, heart disease, Parkinson's and a range of cancers, as well as impairments of ageing such as reduced mobility and cognitive ability are all caused or exacerbated by oxidative stress. With some exceptions, current medical practices focus on surgical repair or drug therapy to alleviate symptoms of ag ....Genetics of longevity and the delay of post-reproductive senescence. Ageing of the population in the coming decades will cause an increasing health care burden. Diseases of ageing such as Alzheimer's, heart disease, Parkinson's and a range of cancers, as well as impairments of ageing such as reduced mobility and cognitive ability are all caused or exacerbated by oxidative stress. With some exceptions, current medical practices focus on surgical repair or drug therapy to alleviate symptoms of ageing rather than addressing the physiological causes of ageing itself. Our project will provide understanding of natural systems that prevent age-related senescence due to oxidative stress. The goal is to identify novel and natural ways to maximise the fitness, well-being and self-sufficiency of people as they age.Read moreRead less
Does physiological plasticity of individuals render populations resilient to climate change? Abrupt environmental changes can put natural populations at risk of extinction. The project will show to what extent individuals can compensate for temperature changes and thereby render populations resilient to climate change. This research will make theoretical advances and improve the power to predict impacts of future climate change.