A Randomised Trial Of Allowing Men Who Have Sex With Men To Have HIV And Syphilis Tests Between Clinic Consultations.
Funder
National Health and Medical Research Council
Funding Amount
$381,414.00
Summary
Rates of HIV and syphilis are rising in gay men in Australia. If these men have HIV and syphilis blood tests more frequently this is likely to reduce the spread of these infections. This trial tests the hypothesis that increased access to testing will increase the rate of testing. We are comparing the rate of testing in 420 gay men, half of whom are allowed to test whenever they choose, without having another clinical consultation.
Women Consider Retirement: A Critical Investigation of Attitudes Towards Work, Ageing and Retirement in Three Generations of Australian Women. The broad aim of this project is to investigate what work and retirement mean for women as they age and to consider the implications of these attitudes, intentions and experiences for government policy, especially given current concerns about workforce maintenance in view of population ageing.
The project will:
- develop a comprehensive understanding ....Women Consider Retirement: A Critical Investigation of Attitudes Towards Work, Ageing and Retirement in Three Generations of Australian Women. The broad aim of this project is to investigate what work and retirement mean for women as they age and to consider the implications of these attitudes, intentions and experiences for government policy, especially given current concerns about workforce maintenance in view of population ageing.
The project will:
- develop a comprehensive understanding of the characteristics, attitudes and experiences of three generations of women in relation to work, ageing and retirement
- examine the extent and consequences of generational and geographic differences in attitudes and choices
- explore the complex social and cultural factors shaping these attitudes, choices and consequences.
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Patterns Of Care And Quality Of Life In Patients With Pancreatic Cancer.
Funder
National Health and Medical Research Council
Funding Amount
$680,010.00
Summary
Available evidence suggests that care of patients with pancreatic cancer is variable and dependent on a variety of factors such as geographic location, socioeconomic status and hospital volume. Variability in care may influence survival and quality of life of patients. We propose to conduct a comprehensive study of the management of patients with pancreatic cancer in NSW and, in a substudy in QLD, to determine how variation in management affects patient quality of life.
Quantifying And Understanding Spatial Inequalities In Cancer Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$443,946.00
Summary
Outcomes for people with cancer depend on where they live; typically poorer in rural and socio-economically disadvantaged areas. However we know very little about why these inequalities exist. My proposed program of research develops and applies emerging statistical and spatial techniques to a unique set of registry and research data to examine the contribution of various individual- and area-level factors to cancer outcomes; increasing our capacity to intervene to reduce these inequalities.
Markers Of Androgen Action, Genetic Variation And Prostate Cancer Risk
Funder
National Health and Medical Research Council
Funding Amount
$798,907.00
Summary
This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic va ....This proposal aim to follow up evidence from a number of studies that genetic and non-genetic markers of hormonal action in different periods of a man's life are associated with prostate cancer risk using a collection of three large, independent epidemiologic studies on prostate cancer named the Prostate Cancer Program. A principal objective is to collect exposure data on acne and digit ratio, and genotype cases and controls across the studies of the Prostate Cancer Program for common genetic variants in 4 candidate genes in the hormonal pathway. The established risk factors for prostate cancer are only age, race and family history. We anticipate that this project will cast light on the role of hormones in prostate cancer and that we will identify new markers of risk of prostate cancer and markers of disease aggressiveness. These outcomes will help us identifying men who are at risk for prostate cancer to target screening and surveillance, and plan prevention strategies. Furthermore, they will also form the basis for research on treatment targets.Read moreRead less
Air pollution: do modern statistical model selection techniques make the silent killer speak too loud? Air pollution is estimated to cause 2400 deaths annually in Australia with an associated cost to the community of $17.2 billion. The outcomes of this project will enable an improved understanding of the association between air pollution and mortality in Australia, thereby allowing government, public health authorities, and regulatory agencies to implement better air pollution standards and pro ....Air pollution: do modern statistical model selection techniques make the silent killer speak too loud? Air pollution is estimated to cause 2400 deaths annually in Australia with an associated cost to the community of $17.2 billion. The outcomes of this project will enable an improved understanding of the association between air pollution and mortality in Australia, thereby allowing government, public health authorities, and regulatory agencies to implement better air pollution standards and provide more informed advice to the public on the necessity of avoiding exposure to air pollutants. These two outcomes are particularly important given Australia's ageing population and the fact that the elderly are among those most susceptible to harm from air pollution exposure.Read moreRead less
Travellers visiting friends and relatives: new approaches to understanding and reducing infectious disease risks. Travel is the single most important factor in the spread of infections globally and travellers who visit friends and relatives in their country of birth are at increased risk of infections. This project will provide necessary evidence to guide an effective response to reducing travel-associated infectious disease in this target at-risk group.
Drivers of ageing and adaptive ageing in middle-aged and older adults. This project aims to answer crucial questions about how our early years influence our health and wellbeing in middle and later life. Drawing on one of Australia’s longest running studies of social and emotional development, we link decades of developmental data collected since 1983 to social, emotional, cognitive and physical wellbeing in participants turning 40 (midlife) and 70 (later life). It will provide insight into impo ....Drivers of ageing and adaptive ageing in middle-aged and older adults. This project aims to answer crucial questions about how our early years influence our health and wellbeing in middle and later life. Drawing on one of Australia’s longest running studies of social and emotional development, we link decades of developmental data collected since 1983 to social, emotional, cognitive and physical wellbeing in participants turning 40 (midlife) and 70 (later life). It will provide insight into important and largely unanswered questions about the way social factors in the first half of life shape our later selves. This study will inform government and health policy targeting ageing populations.
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Healthy and working life expectancies in an ageing Australia. This project aims to identify social circumstances that optimise healthy and working life years in Australia. The project draws on international multidisciplinary expertise to critically evaluate social variation and inequalities in the years older adults live in good health and are engaged in work. Expected outcomes include the generation of new policy-relevant knowledge on older workers, active retirement, and healthy ageing which w ....Healthy and working life expectancies in an ageing Australia. This project aims to identify social circumstances that optimise healthy and working life years in Australia. The project draws on international multidisciplinary expertise to critically evaluate social variation and inequalities in the years older adults live in good health and are engaged in work. Expected outcomes include the generation of new policy-relevant knowledge on older workers, active retirement, and healthy ageing which will advance the field of life course epidemiology and inform the debate about Australia’s future ageing. This project should provide benefits for individual wellbeing, and provide evidence that can inform long-term public policy on health, work, welfare, and retirement.Read moreRead less
Environmental Risk Factors For Iron Overload-related Disease In A Cohort Study Of Hereditary Haemochromatosis
Funder
National Health and Medical Research Council
Funding Amount
$152,936.00
Summary
Results published last year from our Melbourne HealthIron study of hereditary haemochromatosis (iron overload disease) show that almost one third of the 50,000 men genetically at risk of iron overload in Australia will develop symptoms of disease including fatigue, arthritis and liver damage. We will use data from the recent follow-up of the Health2020 cohort, of which HealthIron is a sub-study, to determine environmental risk factors for progression to disease in people with iron overload.