Reduction Of Chronic Post-surgical Pain With Ketamine - ROCKet Study
Funder
National Health and Medical Research Council
Funding Amount
$4,823,395.00
Summary
Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.
Physical, Lifestyle And Psychosocial Determinants Of Spinal Pain Development In Adolescents
Funder
National Health and Medical Research Council
Funding Amount
$682,800.00
Summary
This project aims to understand the development of back and neck pain in adolescence. By the age of 16 around half of all adolescents have suffered back pain and one third have suffered neck pain. For many adolescents this pain is disabling and over a third of sufferers miss school, miss recreation and seek medical help. The current understanding of back and neck pain in adolescence is quite limited - restricting the effectiveness of initiatives to prevent adolescents having to suffer spinal pai ....This project aims to understand the development of back and neck pain in adolescence. By the age of 16 around half of all adolescents have suffered back pain and one third have suffered neck pain. For many adolescents this pain is disabling and over a third of sufferers miss school, miss recreation and seek medical help. The current understanding of back and neck pain in adolescence is quite limited - restricting the effectiveness of initiatives to prevent adolescents having to suffer spinal pain and of treatment of those adolescents unlucky enough to have an episode. Better understanding and interventions for adolescent spinal pain will also have longer term implications by reducing adult spinal pain. Four out of 5 adults will experience spinal pain. In the USA treating adult back pain is the 4th largest health care cost. Many adults with chronic back pain had their first episode during adolescence. A better understanding of spinal pain in adolescence may help prevent it developing into a lifelong disability. We will collect information from 2,000 adolescents on their experience of back and neck pain and on potential physical, lifestyle and psychosocial risk factors. We believe factors such as their posture, muscle capacity, TV and computer use, mental health and social situation all combine to influence whether a person develops back or neck pain. The project is unique as it will not only collect a broad range of information during adolescence, but will also make use of a large database of health, developmental and psychosocial information already collected from these children since birth. With a better understanding of the development of spinal pain we will be able to develop guidelines to help prevent these problems. We will also be able to develop better treatment plans for sub-groups of adolescents with a particular combination of risk factors. Together these initiatives will assist in understanding and breaking the pathway to chronic spinal pain.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100206
Funder
Australian Research Council
Funding Amount
$423,154.00
Summary
Pain: Open to interpretation? This project aims to determine how pain interpretation drives pain experience, using rigorous state-of-the-art lab research. This project expects to generate new knowledge about the psychological mechanisms maintaining pain experience and avoidance behaviour, using novel techniques to measure interpretation of pain sensations. Expected outcomes include the development of an evidence-based psychological model of pain interpretation, enhanced capacity to build interna ....Pain: Open to interpretation? This project aims to determine how pain interpretation drives pain experience, using rigorous state-of-the-art lab research. This project expects to generate new knowledge about the psychological mechanisms maintaining pain experience and avoidance behaviour, using novel techniques to measure interpretation of pain sensations. Expected outcomes include the development of an evidence-based psychological model of pain interpretation, enhanced capacity to build international collaborations, and ecologically valid methods for measuring pain interpretation. This research forms a solid platform for further translational research, to build novel, scalable interventions to improve outcomes for the one in five Australians living with chronic pain.Read moreRead less
Technology is changing the lives of Australians. We need to understand the impact on health to gain the benefits with minimal harm. This fellowship will support a program of internationally leading research drawing together ergonomics, physiotherapy and physical activity expertise. Example projects include the impact of electronic games on children’s activity, walking workstations to increase physical activity of office workers and a family-based program for overweight adolescents.
I am a physiotherapist with special expertise in ergonomics. My research aims to improve health outcomes through an understanding the physical impact of new technology use.
Learning Mechanisms and the Development of Dynamic Capabilities within Firms. The project has the following national/community benefits: (1) a more comprehensive study of the specific and unique features of the structure and innovative process operating within a major Australian producer of commodities, (2) a greater understanding of how knowledge can be created and captured in the form of firm-level dynamic capabilities, contributing towards the creation of an effective knowledge and innovation ....Learning Mechanisms and the Development of Dynamic Capabilities within Firms. The project has the following national/community benefits: (1) a more comprehensive study of the specific and unique features of the structure and innovative process operating within a major Australian producer of commodities, (2) a greater understanding of how knowledge can be created and captured in the form of firm-level dynamic capabilities, contributing towards the creation of an effective knowledge and innovation economy, and (3) assisting regional communities by providing specific recommendations for generating learning mechanisms and more importantly, capturing value from learning in terms of process improvement and innovation.Read moreRead less
The link between corporate governance and sustainability: A contingency approach. Australian businesses will experience decreased economic growth, more health issues and fewer international opportunities if sustainability is not addressed. Sustainability is business approach seeking long-term value by embracing opportunities and managing risk from economic, environmental and social developments. This study will provide insight into optimal board structures to oversee performance across economic, ....The link between corporate governance and sustainability: A contingency approach. Australian businesses will experience decreased economic growth, more health issues and fewer international opportunities if sustainability is not addressed. Sustainability is business approach seeking long-term value by embracing opportunities and managing risk from economic, environmental and social developments. This study will provide insight into optimal board structures to oversee performance across economic, environmental and social dimensions. It will also identify the conditions whereby firms can adapt to market transformation, and determine resource reconfigurations that respond to sustainability challenges.Read moreRead less
Innovative approaches to managing and understanding taste and odour in drinking water systems. Taste and odour (T/O) problems resulting from Cyanobacteria can change consumers' perception of product safety, resulting in many complaints, soaring management and treatment costs, and large financial losses, yet little is known about how they arise.
This project will provide the Australian Water Industry with cost-effective, sensitive, specific, rapid and practical tools for managing and understandi ....Innovative approaches to managing and understanding taste and odour in drinking water systems. Taste and odour (T/O) problems resulting from Cyanobacteria can change consumers' perception of product safety, resulting in many complaints, soaring management and treatment costs, and large financial losses, yet little is known about how they arise.
This project will provide the Australian Water Industry with cost-effective, sensitive, specific, rapid and practical tools for managing and understanding T/O episodes, and will also benefit the aquaculture and food sectors, and the research community. An improved ability to manage geosmin in drinking water, will also have positive repercussions on the Australian environment, by eliminating the need to use environmentally controversial control methods such as copper sulphate dosing.
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A multilevel approach to leadership and dynamic capabilities in organisations. The quality of leadership in Australian organisations has an impact on business productivity, international competitiveness, and employee health and well-being. This research will support the development of leadership skills at different organisational levels. For senior leaders, these skills include developing strategy, allocating resources, and supporting innovation. For team leaders, skills include team coordinatio ....A multilevel approach to leadership and dynamic capabilities in organisations. The quality of leadership in Australian organisations has an impact on business productivity, international competitiveness, and employee health and well-being. This research will support the development of leadership skills at different organisational levels. For senior leaders, these skills include developing strategy, allocating resources, and supporting innovation. For team leaders, skills include team coordination, employee support, and creating flexibility. By supporting interventions that build adaptivity and flexibility in organisations, the research will provide resources to support dynamic organisations to be better equipped to compete in demanding international markets.Read moreRead less