Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100079
Funder
Australian Research Council
Funding Amount
$320,000.00
Summary
A haptic-based immersive motion platform for human performance evaluation. A haptic-based immersive motion platform for human performance evaluation: This project aims to establish a motion platform capable of combining continuous centrifugal rotation and large linear displacement with an additional five degrees of motion. The system will house a human subject at the end of a large serial robot similar to a human arm, which can rotate continuously about its base. The robot arm will be installed ....A haptic-based immersive motion platform for human performance evaluation. A haptic-based immersive motion platform for human performance evaluation: This project aims to establish a motion platform capable of combining continuous centrifugal rotation and large linear displacement with an additional five degrees of motion. The system will house a human subject at the end of a large serial robot similar to a human arm, which can rotate continuously about its base. The robot arm will be installed on a large linear axis enabling the simulation of movements and accelerations along a straight path as well as rotation provided by other axes of the robot. The motion platform will comprise audio and visual devices, and haptic-based control mechanisms, for example a steering wheel and pedals or a helicopter cyclic, to provide a number of human immersed scenarios for driving/flying training and human perception evaluation.Read moreRead less
The Australian naturalistic driving study: innovation in road safety research and policy. A revolutionary new approach, the naturalistic driving study, will investigate what people actually do when they drive, in normal and safety-critical situations. It will provide Australia with answers to some intractable, high priority, road safety problems that cannot be answered using current methods, thereby saving hundreds of lives.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100050
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Integrated facility for recording driver and road user behaviour. The integrated facility will be used to record and analyse data on driver and road user behaviour, in normal and safety-critical situations, for thousands of Australian drivers. The data yielded will be used to develop new and improved countermeasures for reducing road deaths and serious injuries on Australian roads.
Determination Of Irradiation Dose Efficacy For Use In Impaction Grafting At Revision Joint Replacement
Funder
National Health and Medical Research Council
Funding Amount
$411,517.00
Summary
Primary hip replacement is a successful intervention for hip disease, but 10-15% of hip prostheses fail and require revision surgery within 10-15 years. At the time of revision, significant bone loss around the failed prosthesis is not uncommon. A bone reconstruction procedure, called impaction grafting, where donor bone is minced and placed in the areas of deficient bone before implanting the new prosthesis, has shown to give good results at more than ten years in some centres. A high incidence ....Primary hip replacement is a successful intervention for hip disease, but 10-15% of hip prostheses fail and require revision surgery within 10-15 years. At the time of revision, significant bone loss around the failed prosthesis is not uncommon. A bone reconstruction procedure, called impaction grafting, where donor bone is minced and placed in the areas of deficient bone before implanting the new prosthesis, has shown to give good results at more than ten years in some centres. A high incidence of early complications of this procedure have included loss of fixation within the bone. Fracture of the bone around prostheses has also reported in some centres. These events require more surgery, putting the patient at higher risk greater complications and longer rehabilitations. Recent improvements in surgical technique and donor bone preparation have improved results. A current debate questions whether the dose of irradiation can be reduced from 25 kGy, while maintaining sterility of allografts. The risk of bacterial contamination in allografts is low, and irradiation reduces the mechanical strength of the graft, contributing to complications when irradiated bone is used. The benefits of decontaminating the bone may be outweighed by the higher risk for failure due to poor bone quality and resulting prosthesis instability. We will use ISO standards to test the validity of radiation dose for sterilising bone ex vivo. In the absence of controlled human studies, our aim is also to compare the results of impaction grafting with non-irradiated bone versus bone irradiated at current doses used by Australian bone banks, and lower doses indicated by ex vivo testing. We will use a large animal model of revision hip replacement, with precise measures of prosthesis stability. The results of this study will guide clinical decisions regarding the efficacy of current bone graft preparation procedures and the use of irradiated bone in human hip replacement surgery.Read moreRead less
Special Research Initiatives - Grant ID: SR0354739
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Network on eRAM: Environmental Risk Assessment and Management. The proposed network seeks to provide an understanding of the relationship between environmental agents/factors and public health. It provides Australia's first, unified effort to undertand the processes involved at a whole-of-environment level. By virtue of its operation, the network will co-ordinate and expand upon the largely scattered and matrix-specific research in this field that currently takes place. It will permit evaluat ....Network on eRAM: Environmental Risk Assessment and Management. The proposed network seeks to provide an understanding of the relationship between environmental agents/factors and public health. It provides Australia's first, unified effort to undertand the processes involved at a whole-of-environment level. By virtue of its operation, the network will co-ordinate and expand upon the largely scattered and matrix-specific research in this field that currently takes place. It will permit evaluation of environmental agents/factors, as they relate to public health under prevailing environmental conditions. Thus, the major outcome of the network will be effective risk assessment of the expected real-time effects of environmental agents/factors on public health.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100175
Funder
Australian Research Council
Funding Amount
$475,000.00
Summary
A high-payload, high-fidelity haptically-enabled motion simulation facility. An Australian-first motion simulation facility consisting of a high-payload, high-fidelity Stewart platform mounted on a dual-axis linear track is proposed. The facility will allow high acceleration and high vibration manoeuvres, and large displacements through an eight-degrees-of-freedom range of motion. It can carry the entire control compartment of a heavy vehicle, a truck, an ambulance, a train, or a multi-operator ....A high-payload, high-fidelity haptically-enabled motion simulation facility. An Australian-first motion simulation facility consisting of a high-payload, high-fidelity Stewart platform mounted on a dual-axis linear track is proposed. The facility will allow high acceleration and high vibration manoeuvres, and large displacements through an eight-degrees-of-freedom range of motion. It can carry the entire control compartment of a heavy vehicle, a truck, an ambulance, a train, or a multi-operator cockpit of a mining vehicle for simulation. The outcome will provide significant benefits for virtual vehicle prototyping and testing, driver training and behaviour modelling, motion perception and motion sickness research; therefore advancing Australia as the global leader in motion simulation and vehicular technologies.Read moreRead less
The Risks And Benefits Of Contemporary Total Hip Replacement
Funder
National Health and Medical Research Council
Funding Amount
$493,530.00
Summary
The number of hip replacements undertaken in Australia is steadily increasing. The most common complications of hip replacements are dislocation and loosening due to bone loss around the implant, requiring complex and expensive revision surgery. This study will investigate the incidence of dislocation and, using a new diagnostic imaging technique, the incidence and amount of bone loss around a relatively new prosthetic material, the outcomes of which are not known despite its increasing use.
Visual tracking of multiple objects: A stochastic geometrical approach. Reliable real-time visual multiple-object tracking techniques will open up new applications that enhance the quality of life such as driving safety, traffic monitoring, home security, security and surveillance of public facilities. These new applications have huge commercial potentials, and the technology developed from this project will provide the catalyst for vibrant new industries to grow. In addition, the expertise deve ....Visual tracking of multiple objects: A stochastic geometrical approach. Reliable real-time visual multiple-object tracking techniques will open up new applications that enhance the quality of life such as driving safety, traffic monitoring, home security, security and surveillance of public facilities. These new applications have huge commercial potentials, and the technology developed from this project will provide the catalyst for vibrant new industries to grow. In addition, the expertise developed from the project will provide a competitive edge for Australian industries in aerospace, oceanography, robotics, remote sensing, and biomedical engineering. Read moreRead less
Legal risk management of adverse health outcomes and injury in the fitness industry: developing evidence-informed regulation that improves safety. This project analyses Australian laws, policies and practices designed to manage legal risks and liabilities in the fitness industry, and assesses their effectiveness in preventing adverse health outcomes, injuries, and the legal liability associated with those risks.