Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560705
Funder
Australian Research Council
Funding Amount
$825,000.00
Summary
Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast ....Advanced Deformation Simulation Laboratory. For Australia to maintain its position as a world leader in the science of metals processing it must have the capability for state-of-the-art physical simulation. The present proposal is for the purchase and installation of two leading edge simulation tools: a high rate/short inter-pass hot deformation simulator and a hot equal channel angular extrusion press. Advanced hot deformation simulation is required for the development and optimisation of "fast" industrial processes and for understanding the complex microstructural reactions associated with them. High temperature extrusion is required for the development of ultra-fine and nano-grained light metals.Read moreRead less
A Tough Resilin Based Hydrogel Platform for Repair and Regeneration. This project seeks to develop novel hydrogels that mimic the properties of the body. In the field of repair and regeneration, our challenge is to make hydrogels that retain the fatigue and resilience properties of the natural body part, but are comprised of nontoxic material. Resilin is a remarkable material exhibiting a broad range of stimuli-responsive behaviour and outstanding elasticity. The project aim is to create a tough ....A Tough Resilin Based Hydrogel Platform for Repair and Regeneration. This project seeks to develop novel hydrogels that mimic the properties of the body. In the field of repair and regeneration, our challenge is to make hydrogels that retain the fatigue and resilience properties of the natural body part, but are comprised of nontoxic material. Resilin is a remarkable material exhibiting a broad range of stimuli-responsive behaviour and outstanding elasticity. The project aim is to create a tough and responsive hydrogel platform from this disordered protein family through greater understanding of structure and mechanical function and incorporating adequate stiffness, strength and biocompatibility. Such tough hydrogels would be applicable to a range of biotechnological applications (eg intervertebral disc repair or artificial skin tissue engineering).Read moreRead less
Development of novel therapies for the treatment of cancer. Both aging and obesity are significant risk factors for cancer and are becoming a burden on the health care budget. The proposed novel cancer therapy will improve current cancer treatments by enhancing their efficacy, thereby reducing the required dose and minimizing side effects. Such an outcome would not only benefit the well being of the individual but would achieve significant health care cost savings.
Cluster hardening of metastable steel alloys produced by thin strip casting. The goal of this project is to generate sufficient knowledge to apply strip casting to a wider range of steel grades and reduce the global energy cost of steel sheet production. Over 1 billion tonnes of steel is produced every year. Direct strip casting is an emerging green technology that reduces the energy required to process liquid steel into thin sheet product by up to 90 per cent. This study plans to use advanced a ....Cluster hardening of metastable steel alloys produced by thin strip casting. The goal of this project is to generate sufficient knowledge to apply strip casting to a wider range of steel grades and reduce the global energy cost of steel sheet production. Over 1 billion tonnes of steel is produced every year. Direct strip casting is an emerging green technology that reduces the energy required to process liquid steel into thin sheet product by up to 90 per cent. This study plans to use advanced atomic-scale characterisation techniques such as atom probe tomography and high-resolution electron microscopy to understand the non-equilibrium microstructures that develop as a result of the extremely rapid cooling rates experienced during strip casting.Read moreRead less
Investigating the evolution of innate and adaptive cellular immunity. This proposal aims to assess the impact of geographical and genetic isolation of the Australian Indigenous population on adaptive and innate immune systems. The project will use novel DNA sequencing approaches to generate the high resolution sequences of two genetic loci that regulate innate and adaptive immune responses, the major histocompatibility complex locus and the killer cell immunoglobulin-like receptor locus. In an i ....Investigating the evolution of innate and adaptive cellular immunity. This proposal aims to assess the impact of geographical and genetic isolation of the Australian Indigenous population on adaptive and innate immune systems. The project will use novel DNA sequencing approaches to generate the high resolution sequences of two genetic loci that regulate innate and adaptive immune responses, the major histocompatibility complex locus and the killer cell immunoglobulin-like receptor locus. In an initial screen, distinct variants and combinations of these genes were identified. This project aims to interrogate how variation in these critical genes impacts on the function of cytotoxic lymphocytes, providing insights into the evolutionary drivers of immune recognition mechanisms.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668504
Funder
Australian Research Council
Funding Amount
$648,000.00
Summary
Real-time Observation of Thermal and Mechanical Response at the Nano Level. The requested facility is an electron microscope dedicated to observing, in real-time, the nano-scale mechanisms that control the response of materials to stress and temperature. The insight provided by this facility is needed for the development of the next generation of materials, particularly "nano" materials based on particles, fibres, whiskers, nano-tubes, thin films and other micro-formed parts. These materials wil ....Real-time Observation of Thermal and Mechanical Response at the Nano Level. The requested facility is an electron microscope dedicated to observing, in real-time, the nano-scale mechanisms that control the response of materials to stress and temperature. The insight provided by this facility is needed for the development of the next generation of materials, particularly "nano" materials based on particles, fibres, whiskers, nano-tubes, thin films and other micro-formed parts. These materials will underpin the next generation of technological advances and new applications such as nano-machines. The facility will also be used to train the future scientists who will develop these exciting new technologies.Read moreRead less
Scalable Graphene Enabled Smart Composites. The need for lightweight composite materials is increasing exponentially in the context of renewable energy, e-mobility and related emission reductions. This project aims to develop novel approaches to integrate graphene nanomaterials into structural composites, enabling damage sensing and structural health monitoring functionalities. The outcome of this project will be a new class of smart composites that will address the critical need for improving s ....Scalable Graphene Enabled Smart Composites. The need for lightweight composite materials is increasing exponentially in the context of renewable energy, e-mobility and related emission reductions. This project aims to develop novel approaches to integrate graphene nanomaterials into structural composites, enabling damage sensing and structural health monitoring functionalities. The outcome of this project will be a new class of smart composites that will address the critical need for improving structural integrity, safety and reliability, while significantly reducing lifecycle costs. This should provide significant benefits in creating confidence to increase investment in Australia for manufacturing graphene enabled smart materials and technologies with enormous export potential.Read moreRead less
Monitoring, Calibration and Control of a Micro Assembly Process with Machine Vision Systems. A machine vision system will be developed and applied to monitor, calibrate, and control a novel surgical product assembly process of microscale. The machine vision system will benchmark the volumetric information of the needles, calibrate the position of the components, and control the assembly procedures. The successful implementation of the system will assist the production of finer surgical product ....Monitoring, Calibration and Control of a Micro Assembly Process with Machine Vision Systems. A machine vision system will be developed and applied to monitor, calibrate, and control a novel surgical product assembly process of microscale. The machine vision system will benchmark the volumetric information of the needles, calibrate the position of the components, and control the assembly procedures. The successful implementation of the system will assist the production of finer surgical products.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100052
Funder
Australian Research Council
Funding Amount
$870,000.00
Summary
Hybrid testing facility for structures under extreme loads. This unique testing facility will provide a regional and national focus for large three dimensional static and dynamic testing of components, systems and infrastructure used in civil engineering, mining and railways as well as in the aerospace and automotive industries.