Protecting Australia’s food future: shared responsibility for biosecurity. This project aims to investigate whether Australia’s ‘shared responsibility’ approach to biosecurity is capable of facing the growing threat from exotic pests and diseases. Through the analysis of policy documents and the use of semi-structured interviews, this project intends to contribute to a deeper understanding of the inter- and intra-organisational characteristics that influence implementation of biosecurity. Expect ....Protecting Australia’s food future: shared responsibility for biosecurity. This project aims to investigate whether Australia’s ‘shared responsibility’ approach to biosecurity is capable of facing the growing threat from exotic pests and diseases. Through the analysis of policy documents and the use of semi-structured interviews, this project intends to contribute to a deeper understanding of the inter- and intra-organisational characteristics that influence implementation of biosecurity. Expected outcomes include crucial insights into the capacity of a shared responsibility approach to protect agri-food production against biological threats, and the forms of institutional change that may be needed to enhance responsiveness to those threats. This in turn will benefit Australia's biosecurity system.Read moreRead less
Manipulating plant root exudation for soil-borne disease control. This project expects to fundamentally advance analysis and manipulation of root exudation, determine influence of rhizosphere microbiota on exudation, molecular responses to resting spore stimulation and to develop novel disease controls. Expected outcomes of this project include the demonstrated potential of novel disease mitigation and student training in innovative approaches to plant pathology and analytical chemistry. This sh ....Manipulating plant root exudation for soil-borne disease control. This project expects to fundamentally advance analysis and manipulation of root exudation, determine influence of rhizosphere microbiota on exudation, molecular responses to resting spore stimulation and to develop novel disease controls. Expected outcomes of this project include the demonstrated potential of novel disease mitigation and student training in innovative approaches to plant pathology and analytical chemistry. This should provide significant benefits, such as effective disease management tools.Read moreRead less
Investigating the genetic basis for heterogeneous susceptibility of Tasmanian devils to a novel infectious cancer. This project will use genetics and modelling to reveal why Tasmanian devils in northwest Tasmania are not dying from facial tumour disease, a new, unusual infectious cancer threatening this iconic carnivore with extinction. This project will predict extinction risk, develop management options, and provide a new template for managing emerging wildlife diseases.
Understanding fish-killing mechanisms by harmful algal blooms: towards the design of effective mitigation strategies. Fish-killing microalgal blooms cause multi-million dollar losses to global aquaculture and wild fisheries. This project brings together leading Australian and Canadian research teams, applying sophisticated cell line and biologically active molecule technologies, to elucidate precise fish-kill mechanisms and design effective mitigation strategies.
Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the hos ....Contact Networks, Immunity, and Evolution in Competing Cancer Epidemics. The project aims to evaluate evolutionary interactions between two transmissible cancer epidemics affecting Tasmanian devils and quantify their feedback on infection risk and epidemic behaviour. Using contact tracing and a phylogenetic framework we aim to quantify how tumour lineages evolve with each generation of infection and their effects on susceptibility to infection and disease progression. We expect to reveal the host immuno-genetic basis underpinning cancer suppression and the adaptive capacity of populations in response to infectious diseases. This should significantly improve our ability to understand and manage this and other epidemic outbreaks in wildlife, as well as advancing our knowledge in cancer ecology and evolution.Read moreRead less
Effects of invasive macrofauna on marine biodiversity and ecosystem function. The project will identify environmental and biological factors that help prevent invasion of native marine communities by introduced pests, and describe thresholds in marine systems where further loss of macrofaunal species results in declines in ecosystem health.
Conserving wildlife at landscape-scales. The project aims to conserve threatened wildlife at large scales in unfenced landscapes. Using empirical field experiments in Australia and New Zealand, the project will test how suppressing populations of invasive prey – rabbits – could reduce the effect of invasive predators – cats – on native wildlife. Feral cats threaten biodiversity globally, including Australia and New Zealand. Effective control of cats is difficult at large-scales but rabbit contro ....Conserving wildlife at landscape-scales. The project aims to conserve threatened wildlife at large scales in unfenced landscapes. Using empirical field experiments in Australia and New Zealand, the project will test how suppressing populations of invasive prey – rabbits – could reduce the effect of invasive predators – cats – on native wildlife. Feral cats threaten biodiversity globally, including Australia and New Zealand. Effective control of cats is difficult at large-scales but rabbit control is feasible. The project aims to provide a conceptual approach for biodiversity conservation that can be scaled up to mitigate the effects of invasive predators at large scales globally and allow restoration of ecosystems.Read moreRead less
Disease in endangered species: The importance of multiple-host infection and spatial structure. Pathogens are increasingly recognised as threats to endangered species. Managing such threats requires models to assess alternative strategies. Most current models deal with a single host and single pathogen, without spatial structure, although multiple-host pathogens pose the greatest conservation threats. This project develops a new generation of spatially-structured multiple-host models, and applie ....Disease in endangered species: The importance of multiple-host infection and spatial structure. Pathogens are increasingly recognised as threats to endangered species. Managing such threats requires models to assess alternative strategies. Most current models deal with a single host and single pathogen, without spatial structure, although multiple-host pathogens pose the greatest conservation threats. This project develops a new generation of spatially-structured multiple-host models, and applies them to two case studies. The first is the chytrid fungus that is thought to have lead to widespread declines and extinctions of frogs in Australia and overseas. The second is birdpox and malaria that have led to the extinction and endangerment of much of Hawaii's endemic avifauna.Read moreRead less
Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimi ....Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimilate these metals is critical to the generation and aggressiveness of the toxins produced. These processes will be investigated in this study and conceptual and mathematical models will be developed which will assist in assessing management options for estuarine and coastal environments.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.