Investigations into and development of an intelligent decision support system for general practitioners in home-based sleep disorder diagnosis. Sleep disorders cost the Australian health system an estimated $40 million per year. General practitioner's surgeries are not well equipped to deal with diagnosis and the majority of the referrals to specialists are unnecessary. This research will investigate and develop an intelligent decision support system to provide a cost effective solution to thi ....Investigations into and development of an intelligent decision support system for general practitioners in home-based sleep disorder diagnosis. Sleep disorders cost the Australian health system an estimated $40 million per year. General practitioner's surgeries are not well equipped to deal with diagnosis and the majority of the referrals to specialists are unnecessary. This research will investigate and develop an intelligent decision support system to provide a cost effective solution to this problem. The developed software application will enable sleep study to be carried out at home, enabling general practitioners to conduct a preliminary diagnosis. Benefits include a reduction in the costs incurred in travel, time off work and at hospital sleep care centres for people in remote areas.Read moreRead less
Advanced Bayesian Networks for Epidemiology. We will demonstrate the potential of advanced Artificial Intelligence for medical informatics by extending the capabilities of Bayesian Networks. Bayesian Networks excel when researchers need to combine causal and diagnostic reasoning in areas characterised by uncertainty. But they have one flaw which hinders their use: they do not yet easily mix continuous and discrete variables. We will extend them to handle such mixes, then demonstrate how much the ....Advanced Bayesian Networks for Epidemiology. We will demonstrate the potential of advanced Artificial Intelligence for medical informatics by extending the capabilities of Bayesian Networks. Bayesian Networks excel when researchers need to combine causal and diagnostic reasoning in areas characterised by uncertainty. But they have one flaw which hinders their use: they do not yet easily mix continuous and discrete variables. We will extend them to handle such mixes, then demonstrate how much they can improve on current methods for predicting, among other things, coronary heart disease (CHD).Read moreRead less
Special Research Initiatives - Grant ID: SR0567493
Funder
Australian Research Council
Funding Amount
$99,146.00
Summary
E-Services for Comparative Studies in Molecular Biology. The central challenge of post-genomic biology is to exploit the range of sequence and microarray data to yield greater understanding of biological processes. Large comparative studies are hamstrung by the inaccessibility of specialist comparative tools and the problem of managing large-scale disparate data. This project will provide portal and web services facilities to remove these obstacles, relying on robust and scalable business techno ....E-Services for Comparative Studies in Molecular Biology. The central challenge of post-genomic biology is to exploit the range of sequence and microarray data to yield greater understanding of biological processes. Large comparative studies are hamstrung by the inaccessibility of specialist comparative tools and the problem of managing large-scale disparate data. This project will provide portal and web services facilities to remove these obstacles, relying on robust and scalable business technologies to be made freely available. Our work will be driven by specific applications in bacterial genomics and cancer research, and will support research into prostate cancer and the pathogens Chlamydia and Bacillus anthracis.Read moreRead less
Computational techniques for protease research. Protease research is an area of intensive research in Australia. Correctly assessing the mechanisms of protease function is crucial not only for improving our health through medical research and drug development, but also to multiple national areas of research and development, including biotechnology, agriculture, and industries such as the dairy industry. This project will develop innovative computational techniques to advance understanding of h ....Computational techniques for protease research. Protease research is an area of intensive research in Australia. Correctly assessing the mechanisms of protease function is crucial not only for improving our health through medical research and drug development, but also to multiple national areas of research and development, including biotechnology, agriculture, and industries such as the dairy industry. This project will develop innovative computational techniques to advance understanding of how proteases function by redressing a common research assumption that can significantly affect the accuracy of protease function prediction. The outcomes will improve fundamental research into proteases, and enable improved research and development in the many fields that rely on protease work.Read moreRead less
New approaches to functional and structural genomics. Genome sequencing has revealed complete sets of macromolecules that make up our cells. We now need to learn how these macromolecules work together in a coordinated fashion. The proposed research will lead to the discovery of new biological molecules, interactions and processes essential for the function of cells, identify new therapeutic targets and strategies to combat disease, identify new concepts in bio- and nanotechnology, and train new ....New approaches to functional and structural genomics. Genome sequencing has revealed complete sets of macromolecules that make up our cells. We now need to learn how these macromolecules work together in a coordinated fashion. The proposed research will lead to the discovery of new biological molecules, interactions and processes essential for the function of cells, identify new therapeutic targets and strategies to combat disease, identify new concepts in bio- and nanotechnology, and train new interdisciplinary researchers. It will underpin the National Research Priorities (Frontier Technologies for Building and Transforming Australian Industries, and Promoting and Maintaining Good Health) and help Australia capitalise on a plethora of opportunities for future economic and health benefits.Read moreRead less
Precision Pulsar Timing and its Applications. The rapidly rotating pulsars known as millisecond pulsars have period stabilities which rival that of the best terrestrial clocks. Observations of many millisecond pulsars spread across the sky should allow detection of the gravitational-wave background - likely to be the first direct detection of gravity waves. It will also enable establishment of a long-term time standard which is independent of and probably superior to that derived from terrestria ....Precision Pulsar Timing and its Applications. The rapidly rotating pulsars known as millisecond pulsars have period stabilities which rival that of the best terrestrial clocks. Observations of many millisecond pulsars spread across the sky should allow detection of the gravitational-wave background - likely to be the first direct detection of gravity waves. It will also enable establishment of a long-term time standard which is independent of and probably superior to that derived from terrestrial clocks. New analysis techniques and establishment of an international observing network will be required. Investigation and application of techniques for overcoming radio interference will be an important part of the project.Read moreRead less
Defeating Radio Frequency Interference. The radio spectrum is a valuable resource. Development of techniques which minimize the impact of various users on one another, allowing this resource to be shared, will benefit the entire community. For astronomy in particular, shared use is essential because of the very wide bandwidths needed to obtain sufficient sensitivity. Usage of the radio spectrum is increasing rapidly and radio telescopes are becoming more and more sensitive, compounding the probl ....Defeating Radio Frequency Interference. The radio spectrum is a valuable resource. Development of techniques which minimize the impact of various users on one another, allowing this resource to be shared, will benefit the entire community. For astronomy in particular, shared use is essential because of the very wide bandwidths needed to obtain sufficient sensitivity. Usage of the radio spectrum is increasing rapidly and radio telescopes are becoming more and more sensitive, compounding the problems. The digital signal processing techniques developed under this project will be widely applicable, not only to future radio astronomy facilities such as the Square Kilometer Array, but also to the communications industry generally.Read moreRead less
Domain-Driven Actionable Link Discovery. Driven by emergent data mining applications such as detecting terrorist and distributed fraudulent activities, this project will deliver effective techniques and algorithms for discovering isolated yet important links dispersed across related enterprise information systems. The outcomes will enable Australia to play a significant role in the new link discovery area. They will empower Australian organizations with powerful data mining capabilities to deal ....Domain-Driven Actionable Link Discovery. Driven by emergent data mining applications such as detecting terrorist and distributed fraudulent activities, this project will deliver effective techniques and algorithms for discovering isolated yet important links dispersed across related enterprise information systems. The outcomes will enable Australia to play a significant role in the new link discovery area. They will empower Australian organizations with powerful data mining capabilities to deal with critical cross-organization problems, for instance, counter-terrorism, cross-market surveillance, auditing surveillance and social network analysis. They will enhance Australian social security, compliance and life quality through smart information use.Read moreRead less
Pattern Discovery of Discriminating Behaviour Associated with Hidden Communities. A sound understanding of discriminating behaviour in hidden communities, e.g. market manipulation, is essential for effective intervention and prevention. This project will deliver novel and workable algorithms and tools for modelling and pattern discovery of such behaviour. This will safeguard Australia by tackling crucial business and social issues like abnormal trading, online crime and terrorism, thereby enhanc ....Pattern Discovery of Discriminating Behaviour Associated with Hidden Communities. A sound understanding of discriminating behaviour in hidden communities, e.g. market manipulation, is essential for effective intervention and prevention. This project will deliver novel and workable algorithms and tools for modelling and pattern discovery of such behaviour. This will safeguard Australia by tackling crucial business and social issues like abnormal trading, online crime and terrorism, thereby enhancing public confidence, compliance and security in both the economy and society, by preventing and reducing economic and social impact. It will create skills and outcomes to further Australia's leadership in managing emerging data mining challenges and applications, and will deepen collaboration with eminent researchers worldwide.Read moreRead less
Special Research Initiatives - Grant ID: SR0354895
Funder
Australian Research Council
Funding Amount
$40,000.00
Summary
Financial Integrity Research Network (FIRN). FIRN will be directed towards innovation in the integrity and efficiency of Australia's financial system. To address pressing problems and threats associated with this key component of Australia's infrastructure, FIRN will bring together a multi-disciplinary network featuring internationally renowned academics in a unique collaborative research effort which will cross conventional disciplinary boundaries including financial economics, applied statist ....Financial Integrity Research Network (FIRN). FIRN will be directed towards innovation in the integrity and efficiency of Australia's financial system. To address pressing problems and threats associated with this key component of Australia's infrastructure, FIRN will bring together a multi-disciplinary network featuring internationally renowned academics in a unique collaborative research effort which will cross conventional disciplinary boundaries including financial economics, applied statistics, actuarial science, financial mathematics, market micro-structure, accounting and information systems. FIRN will be supported by SIRCA's world-class financial research infrastructure and industry network. It will deliver a range of innovative research, educational, professional development and applied outcomes.Read moreRead less