Industrial Transformation Training Centres - Grant ID: IC180100021
Funder
Australian Research Council
Funding Amount
$4,163,359.00
Summary
ARC Training Centre for the Development of Tools for Fragment Based Design. The ARC Training Centre for the Development of Tools for Fragment Based Design aims to inspire the next generation of drug discovery research leaders. It plans to provide direct experience with industry partners, training and master classes in early stage drug-discovery from industry experts. The Centre is expected to accelerate research translation and industry engagement by providing an efficient strategy for the scree ....ARC Training Centre for the Development of Tools for Fragment Based Design. The ARC Training Centre for the Development of Tools for Fragment Based Design aims to inspire the next generation of drug discovery research leaders. It plans to provide direct experience with industry partners, training and master classes in early stage drug-discovery from industry experts. The Centre is expected to accelerate research translation and industry engagement by providing an efficient strategy for the screening of a biological target and early medicinal chemistry for optimisation. The expected outcome of the Centre is to equip the trainees with the skills to make key contributions to the sustainability and growth of the sector and to provide significant capacity to address global challenges for 21st century pharmaceutical innovation.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH220100017
Funder
Australian Research Council
Funding Amount
$4,808,669.00
Summary
ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals. Radiopharmaceuticals are emerging as next generation medical technologies for addressing complex health challenges, and their manufacture offers significant economic benefit to Australia. The ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals (AMTAR) aims to establish a manufacturing platform for new medical technologies combining innovations in biotechnology and pharmaceutical science. The progra ....ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals. Radiopharmaceuticals are emerging as next generation medical technologies for addressing complex health challenges, and their manufacture offers significant economic benefit to Australia. The ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals (AMTAR) aims to establish a manufacturing platform for new medical technologies combining innovations in biotechnology and pharmaceutical science. The program addresses industry-led challenges for translation of biologics as molecular radiopharmaceuticals, building capacity in biomanufacturing, radiobiology and radiochemistry. The program establishes a dedicated manufacturing pipeline, future-proofing production and securing supply chain of next generation medical technologies.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100016
Funder
Australian Research Council
Funding Amount
$3,123,492.00
Summary
ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therap ....ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therapeutics. The use of an individual patient’s cellular and molecular research findings will ultimately enable personalised diagnostic and therapeutic decisions.Read moreRead less
Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliance ....Confronting everyday harms: preventing abuse of people with disability. The findings of the Disability Royal Commission necessitate new approaches to prevent violence, abuse, neglect and exploitation. Framed by recognition theory, this project proposes empirical research with young people with cognitive disability, using a new concept of ‘everyday harms’ in their paid relationships. The results will inform early responses to poor quality interactions in disability support. The strategic alliances with the government, industry and community partners will develop a practice framework to prevent everyday harms and the escalation to abuse, and to promote safety and wellbeing. The research has policy benefits for capacity-building in the sector to act on the rights and voices of people with disability. Read moreRead less
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revol ....ARC Centre of Excellence in Convergent Bio-Nano Science and Technology. The CoE in Convergent Bio-Nano Science &Technology comprises a multi-disciplinary team focused on research aiming to understand and control the interface of materials with biological systems. The Centre will exploit knowledge of the bio-nano interface to design materials that transport and deliver vaccines, drugs and gene therapy agents, and to design new diagnostic agents and devices. Nanomedicines are on the cusp of revolutionizing diagnosis and therapy in many diseases. The CoE will be the focus of bio-nano research activity in Australia, uniting universities, research agencies, institutes and companies. The expected outcomes are better diagnostic and therapeutic tools designed via an enhanced understanding of the bio-nano-interface.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100009
Funder
Australian Research Council
Funding Amount
$3,317,500.00
Summary
ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste ....ARC Research Hub for Microrecycling of battery and consumer wastes . This project aims to transform Australia’s waste and resource recovery industry by equipping it with scientifically developed advanced manufacturing capability, focusing on small-scale processing of materials produced from battery and consumer wastes which would otherwise mostly end up in landfill. The project will deliver new knowledge in high-temperature reactions of waste and selective synthesis techniques to transform waste into valuable materials and products, including metallic alloys, oxides and carbon. Expected outcomes include industry adoption of commercially viable technology and processes where low value or complex waste is reformed into higher value materials, creating jobs and significant environmental and social benefits.Read moreRead less
Synthesis of Activated Carbon Supported Zero Valent Iron Nanoparticles and Application to Contaminant Degradation in Benthic Sediments. Sediment contamination is a major problem in harbours and estuaries around Australia. For example, in Sydney Harbour, a total fishing ban has been implemented as a result of excessive levels of dioxins and benzofurans in fish tissues. There is also concern at the possibility of large scale contamination of Botany Bay as a result of historic industrial activity a ....Synthesis of Activated Carbon Supported Zero Valent Iron Nanoparticles and Application to Contaminant Degradation in Benthic Sediments. Sediment contamination is a major problem in harbours and estuaries around Australia. For example, in Sydney Harbour, a total fishing ban has been implemented as a result of excessive levels of dioxins and benzofurans in fish tissues. There is also concern at the possibility of large scale contamination of Botany Bay as a result of historic industrial activity around the Bay. While dredging and on-land treatment of sediments is being adopted at the most severely contaminated sites, the cost of this approach is exorbitant. For sites where removal of contaminated sediments cannot be justified, the approach proposed in this study of a technology that entraps contaminants and enhances their in situ biodegradation is potentially a way forward.Read moreRead less
Transforming charity to reduce persistent poverty. This project aims to produce empirical knowledge to assist charities to reduce persistent poverty in Australia. In Australia people in poverty use charity to subsidise limited incomes and survive on a day-to-day basis. Recently charities are expected to assist in disrupting poverty in addition to poverty relief. However there is limited knowledge about how charities work with people who are poor and how they can change to work better. This proje ....Transforming charity to reduce persistent poverty. This project aims to produce empirical knowledge to assist charities to reduce persistent poverty in Australia. In Australia people in poverty use charity to subsidise limited incomes and survive on a day-to-day basis. Recently charities are expected to assist in disrupting poverty in addition to poverty relief. However there is limited knowledge about how charities work with people who are poor and how they can change to work better. This project expects to provide knowledge that governments, social service providers, and charities can use to transform their work with people in poverty. Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100048
Funder
Australian Research Council
Funding Amount
$466,097.00
Summary
Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway ....Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway and reduced energy for both ammonia production and removal. Recovered ammonia expects to produce valuable products, supporting agriculture industry and hydrogen economy. The developed membranes should enable water industry's shift into circular economy, providing significant economic and environmental benefits to Australia.Read moreRead less
Autotransporter assembly: new insights and biotechnological potential. The objective of this project is to improve our understanding of a fundamental biological problem: how autotransporters are assembled into cellular membranes. Autotransporters are a large family of bacterial proteins that play key roles in the pathogenesis of several infectious diseases. Currently, the precise mechanism by which disease-causing molecules are assembled into the outer membranes of bacteria and mitochondria is p ....Autotransporter assembly: new insights and biotechnological potential. The objective of this project is to improve our understanding of a fundamental biological problem: how autotransporters are assembled into cellular membranes. Autotransporters are a large family of bacterial proteins that play key roles in the pathogenesis of several infectious diseases. Currently, the precise mechanism by which disease-causing molecules are assembled into the outer membranes of bacteria and mitochondria is poorly understood. The knowledge that the project develops may inform future strategies aimed at the rational treatment of bacterial and mitochondrial diseases.Read moreRead less