New Methods in Theory and Cosmic Applications of Spherical Random Fields. This project aims to investigate and model spherical random fields which are described as solutions of stochastic differential equations on a sphere or a ball. The project plans to study properties and develop spectral analysis of these solutions. It then plans to use the obtained theoretical results to construct new methods for numerical approximation and statistical estimation of these random fields. In particular, it pl ....New Methods in Theory and Cosmic Applications of Spherical Random Fields. This project aims to investigate and model spherical random fields which are described as solutions of stochastic differential equations on a sphere or a ball. The project plans to study properties and develop spectral analysis of these solutions. It then plans to use the obtained theoretical results to construct new methods for numerical approximation and statistical estimation of these random fields. In particular, it plans to develop novel asymptotic and statistical methodology for tensor random fields. The project will apply the results to model and analyse cosmic microwave background data. Expected outcomes will improve the accuracy in determining cosmological parameters and provide novel tools for better understanding of the universe during its early stages.Read moreRead less
The mathematics of novel magnetic memory materials. Magnetic memories are the world’s principal device for storing information. The next generation will have greatly increased access speed and data-storage capacity. This project will develop the mathematical theory of these new magnetic memory materials, a crucial first step in understanding and being able to fine-tune their properties.
ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this ....ARC Centre of Excellence for Mathematical and Statistical Frontiers of Big Data, Big Models, New Insights. In today's world, massive amounts of data in a variety of forms are collected daily from a multitude of sources. Many of the resulting data sets have the potential to make vital contributions to society, business and government, as well as impact on international developments, but are so large or complex that they are difficult to process and analyse using traditional tools. The aim of this Centre is to create innovative mathematical and statistical models that can uncover the knowledge concealed within the size and complexity of these big data sets, with a focus on using the models to deliver insight into problems vital to the Centre's Collaborative Domains: Healthy People, Sustainable Environments and Prosperous Societies.Read moreRead less
Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of ....Classification of Microarray Gene-Expression Data. The broad aim is to provide statistical methodology for the classification of microarray gene-expression data. Microarrays are part of a new biotechnology that allows the monitoring of expression levels for thousands of genes simultaneously. The explosion in microarrays has produced massive quantities of data that require new statistical techniques for analysis in order to exploit their enormous scientific potential. One of the main uses of the methodology to be developed is to expedite the discovery of new subclasses of diseases. Another is to provide prediction rules for the diagnosis and treatment of diseases.Read moreRead less
New Directions in Bayesian Statistics: formulation, computation and application to exemplar challenges. Bayesian statistics is a fundamental statistical and machine learning approach for density estimation, data analysis and inference. However, there remain open questions regarding the formulation of the model, the likelihood and priors, and efficient computation. This project proposes new approaches that address these issues, and applies them to two exemplar challenges: the impact of climate ch ....New Directions in Bayesian Statistics: formulation, computation and application to exemplar challenges. Bayesian statistics is a fundamental statistical and machine learning approach for density estimation, data analysis and inference. However, there remain open questions regarding the formulation of the model, the likelihood and priors, and efficient computation. This project proposes new approaches that address these issues, and applies them to two exemplar challenges: the impact of climate change on the Great Barrier Reef and better understanding neurological diseases related aging, in particular Parkinson's Disease. Read moreRead less
Robust inferences for analysis of longitudinal data. This project will develop novel statistical tools. Outcomes of this project will enable more reliable data analysis and more cost effective designs in environmental and biological studies.
Cross-Entropy Methods in Complex Biological Systems. The Cross-Entropy method provides a powerful new way to find superior solutions to complicated optimisation problems in biology, ranging from better design and implementation of medical treatments to an increased understanding of complex ecosystems.
Applications of Bayesian methods in Genomics and Comparative Genomics. Bayesian statistics provides a unified and versatile approach to problems of data analysis, inference and hypothesis testing. This project will involve the application of Bayesian methods to four topics of commercial and scientific importance in the fields of Genomics and Comparative Genomics. The four topics are: data analysis for a novel DNA sequencing technology, investigating genomic structure using multiple change-point ....Applications of Bayesian methods in Genomics and Comparative Genomics. Bayesian statistics provides a unified and versatile approach to problems of data analysis, inference and hypothesis testing. This project will involve the application of Bayesian methods to four topics of commercial and scientific importance in the fields of Genomics and Comparative Genomics. The four topics are: data analysis for a novel DNA sequencing technology, investigating genomic structure using multiple change-point analysis, phlogenetic inference with multiple genes and detection of incongruent phylogenies. The overall goal of the project is to advance understanding of the structure, function and evolution of genomes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100741
Funder
Australian Research Council
Funding Amount
$382,274.00
Summary
Tractable Bayesian algorithms for intractable Bayesian problems. This project seeks to develop computationally efficient and scalable Bayesian algorithms to estimate the parameters of complex models and ensure inferences drawn from the models can be trusted. Bayesian parameter estimation and model validation procedures are currently computationally intractable for many complex models of interest in science and technology. These include biological processes such as the efficacy of heart disease, ....Tractable Bayesian algorithms for intractable Bayesian problems. This project seeks to develop computationally efficient and scalable Bayesian algorithms to estimate the parameters of complex models and ensure inferences drawn from the models can be trusted. Bayesian parameter estimation and model validation procedures are currently computationally intractable for many complex models of interest in science and technology. These include biological processes such as the efficacy of heart disease, wound healing and skin cancer treatments. Potential outcomes of the project include new algorithms to significantly economise computations and improved understanding of the mechanisms of experimental data generation. Improved models of wound healing, skin cancer growth and heart physiology supported by these algorithms could improve population health.Read moreRead less
Random Discrete Structures: Approximations and Applications. The behaviour of many real world systems can be modelled by random discrete structures evolving over time. For example, the sizes of populations of frogs in some close patches of forests can be modelled as interacting random processes. The aim of the project is to investigate large discrete random structures that arise from real world application in areas such as biology, complex networks and insurance. The proposed project is at the i ....Random Discrete Structures: Approximations and Applications. The behaviour of many real world systems can be modelled by random discrete structures evolving over time. For example, the sizes of populations of frogs in some close patches of forests can be modelled as interacting random processes. The aim of the project is to investigate large discrete random structures that arise from real world application in areas such as biology, complex networks and insurance. The proposed project is at the interface of mathematics and 'big data' applications and so the work of the project aims to provide theoretical and heuristic underpinnings useful in the algorithms and techniques of practitioners. Understanding the applications in the project requires new, broadly applicable methods and developing such is a complementary aim.Read moreRead less