Natriuretic peptide hormones and the stress response of fish. There are two main benefits of our research to Australia. Firstly, the team that we have assembled have international reputations, and include scientists from overseas. This team will be led by Australian Institutions and will put Australian science in the forefront of a competitive field, internationally. Secondly, our research examines questions that are critical in our understanding of how animals respond to stressful events. T ....Natriuretic peptide hormones and the stress response of fish. There are two main benefits of our research to Australia. Firstly, the team that we have assembled have international reputations, and include scientists from overseas. This team will be led by Australian Institutions and will put Australian science in the forefront of a competitive field, internationally. Secondly, our research examines questions that are critical in our understanding of how animals respond to stressful events. The response to stress, if excessive, leads to ill-health in both humans and other animals. Our research examines new connections between stress and fish biology, which could lead to discoveries that are valuable in managing stress and health in wild and farmed fishes.Read moreRead less
Mechanisms of zinc transport and homeostasis in plants. Zinc deficiency is a widespread factor limiting crop production and affects many soils of southern Australia and around the world. Genetic techniques can be used to identify zinc-efficient crop breeds able to grow well under zinc deficient conditions and able to efficiently deliver zinc to cereal grains to alleviate nutritional zinc-deficiency in humans. This project will identify new genes important in zinc transport and homeostasis in pla ....Mechanisms of zinc transport and homeostasis in plants. Zinc deficiency is a widespread factor limiting crop production and affects many soils of southern Australia and around the world. Genetic techniques can be used to identify zinc-efficient crop breeds able to grow well under zinc deficient conditions and able to efficiently deliver zinc to cereal grains to alleviate nutritional zinc-deficiency in humans. This project will identify new genes important in zinc transport and homeostasis in plants and will ultimately allow their role in zinc efficient crops to be assessed. This will contribute to more rapid and directed strategies in breeding zinc efficient crops.Read moreRead less
Lost at sea? Understanding adaptation and dispersal in spiny lobsters. Continual recruitment of young is fundamental to the replenishment of populations, especially when a stock is fished. Existing theory suggests that species with very long planktonic larval stages disperse widely, ensuring their genes are well mixed. However, recently identified genetic differences between populations of rock lobster challenge this paradigm and demonstrate that despite larvae mixing in the ocean for years, loc ....Lost at sea? Understanding adaptation and dispersal in spiny lobsters. Continual recruitment of young is fundamental to the replenishment of populations, especially when a stock is fished. Existing theory suggests that species with very long planktonic larval stages disperse widely, ensuring their genes are well mixed. However, recently identified genetic differences between populations of rock lobster challenge this paradigm and demonstrate that despite larvae mixing in the ocean for years, local recruitment and/or adaptation are at play. Recent developments in genomics and bioinformatics should allow this project to understand the ecological processes underpinning these genetic signatures and determine their evolutionary implications. Such findings could direct targeted rebuilding of depleted fisheries stocks.Read moreRead less
Striking Gold - Determining the genetics of gold skin colour in barramundi. Barramundi is one of Australia’s finest eating table fish and the species is gaining global prominence. However, fillet flesh colour of Australian farmed barramundi exhibit greyish tones which lowers consumer acceptance compared to other white flesh fish and imported product. Barramundi with rare golden skin tones do not exhibit this flesh "greyness" and are therefore a valuable niche product to farm if they can be produ ....Striking Gold - Determining the genetics of gold skin colour in barramundi. Barramundi is one of Australia’s finest eating table fish and the species is gaining global prominence. However, fillet flesh colour of Australian farmed barramundi exhibit greyish tones which lowers consumer acceptance compared to other white flesh fish and imported product. Barramundi with rare golden skin tones do not exhibit this flesh "greyness" and are therefore a valuable niche product to farm if they can be produced in larger numbers. This project will elucidate the genetic basis and mechanism of expression behind the golden barramundi phenotype. In doing so, it will enable barramundi farmers to produce them at commercially relevant scales, providing them with a substantial competitive advantage in both domestic and global markets.Read moreRead less
Mechanistic characterisation of genotype x environment interactions in sorghum and arabidopsis. Sorghum is an economically important cereal crop for Australia. In Australia, sorghum is used as a staple animal feed and it is very important for the live stock industry. With the predicted changes of temperature and rainfall patterns due to climate change, negative effects on sorghum yield are expected, which can have adverse effects on Australian economy. Our studies will identify and mark genes th ....Mechanistic characterisation of genotype x environment interactions in sorghum and arabidopsis. Sorghum is an economically important cereal crop for Australia. In Australia, sorghum is used as a staple animal feed and it is very important for the live stock industry. With the predicted changes of temperature and rainfall patterns due to climate change, negative effects on sorghum yield are expected, which can have adverse effects on Australian economy. Our studies will identify and mark genes that regulate flowering and seed production in sorghum in response to changes in temperature and light interactions. These studies will help to develop novel sorghum varieties with desirable characters through plant-breeding programmes.Read moreRead less
A novel regulator of growth signalling in Drosophila. This project aims to increase understanding of how growth is regulated by growth factor hormones. In animals, growth is controlled by signalling pathways that are activated by secreted peptide hormones. A new regulator of growth in the fruitfly Drosophila, the membrane attack complex/perforin-like (MACPF) protein Torso-like, has been identified. The project aims to unravel how Torso-like functions to regulate growth, thus throwing light on th ....A novel regulator of growth signalling in Drosophila. This project aims to increase understanding of how growth is regulated by growth factor hormones. In animals, growth is controlled by signalling pathways that are activated by secreted peptide hormones. A new regulator of growth in the fruitfly Drosophila, the membrane attack complex/perforin-like (MACPF) protein Torso-like, has been identified. The project aims to unravel how Torso-like functions to regulate growth, thus throwing light on the role this protein family may play in all animals. The findings are expected to provide key insights into the modification of growth factor activity, which is often dysregulated in human cancers and growth disorders, and may enable the design of new strategies for interfering with insect development for pest control.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775503
Funder
Australian Research Council
Funding Amount
$255,000.00
Summary
Robotics for plant genomics: Increasing throughput in plant genetic analyses. Plant genomics has direct benefit to crop improvement, especially as focussed in the applicants' laboratories. Thus, the Australian agri-food sector will benefit substantially from the acceleration in plant functional genomics that will arise from the installation of the robotics equipment described in the current application, by both underpinning more applied research and also being used directly in crop improvement p ....Robotics for plant genomics: Increasing throughput in plant genetic analyses. Plant genomics has direct benefit to crop improvement, especially as focussed in the applicants' laboratories. Thus, the Australian agri-food sector will benefit substantially from the acceleration in plant functional genomics that will arise from the installation of the robotics equipment described in the current application, by both underpinning more applied research and also being used directly in crop improvement programs such as are based at the Waite Campus. The outputs will include crops with increased tolerance to biotic and abiotic stresses, a reduced dependence on chemical inputs such as fertilisers and improved food quality, with consequent benefits to the environment and human health and nutrition.Read moreRead less
Design and Development of DNA Oligonucleotide Microarrays (Biochips) for Fish Species Identification From Processed Food Products. Australia's seafood industry (valued at A$2 billion/annum) imports and exports a wide variety of fish and shellfish products. This industry is open to exploitation, specifically in respect of product labelling. A rapid and reliable method for identifying commercial and endangered fish species in seafood products is urgently needed for effective management and regulat ....Design and Development of DNA Oligonucleotide Microarrays (Biochips) for Fish Species Identification From Processed Food Products. Australia's seafood industry (valued at A$2 billion/annum) imports and exports a wide variety of fish and shellfish products. This industry is open to exploitation, specifically in respect of product labelling. A rapid and reliable method for identifying commercial and endangered fish species in seafood products is urgently needed for effective management and regulation of the industry. New genetic biochip technology enables any species or strains of an organism to be rapidly, and accurately, identified by non-experts. In collaboration with GeneScan Australia, this project applies this new technology to develop a diagnostic tool for checking the labelling of Australian seafood products.Read moreRead less
Glutathione, a major antioxidant in plants: translocation between tissues and transport within cells. Plants are continually exposed to environmental stress. In agriculture this may include high and low temperature, pathogens, soil toxicity and excess light. The ways in which plants deal with environmental stress influence their productivity. Understanding these mechanisms is an important goal that can contribute to better strategies to manage plant responses to environmental stress in agricultu ....Glutathione, a major antioxidant in plants: translocation between tissues and transport within cells. Plants are continually exposed to environmental stress. In agriculture this may include high and low temperature, pathogens, soil toxicity and excess light. The ways in which plants deal with environmental stress influence their productivity. Understanding these mechanisms is an important goal that can contribute to better strategies to manage plant responses to environmental stress in agricultural species.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100648
Funder
Australian Research Council
Funding Amount
$472,027.00
Summary
Novel reproductive approaches to de-risk and transform barramundi breeding. Demand for Australian seafood outstrips supply. Farming of the iconic Australian barramundi is poised to play a major role addressing this shortfall; but innovative methods are needed to de-risk breeding processes and to provide precise control of maturation, spawning and genetic contribution of broodstock. This project, in partnership with the world’s largest barramundi breeding company, will develop, test and apply nov ....Novel reproductive approaches to de-risk and transform barramundi breeding. Demand for Australian seafood outstrips supply. Farming of the iconic Australian barramundi is poised to play a major role addressing this shortfall; but innovative methods are needed to de-risk breeding processes and to provide precise control of maturation, spawning and genetic contribution of broodstock. This project, in partnership with the world’s largest barramundi breeding company, will develop, test and apply novel breeding methods to obtain tight control over barramundi reproductive development and spawning. By combining cutting-edge genetic and applied breeding techniques, selective breeding programs will be more efficient and the genetic gains from breeding programs will be maximised.Read moreRead less