Alpha-particles linked to recombinant antibodies targeting tumour cells have potential to effectively treat tumours while minimising normal tissue side effects. We will explore a novel alpha-particle therapy approach to solid tumours, by delivering 225Ac directly into tumour cells, or into cells that support the tumour (microenvironment). This approach will hopefully result in development of a new approach to treatment of cancers that are resistant to conventional therapies.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453521
Funder
Australian Research Council
Funding Amount
$508,374.00
Summary
National Heavy Ion Accelerator. The principal objectives are to develop a facility to provide energetic heavy ions for basic science, applications and research training. This will be accomplished through an enhancement of a superconducting linear accelerator using innovative technology, and extension of the available beam species through improvements to a large electrostatic tandem accelerator. The facility provides research resources for a broad range of national and international users.
Industrial Transformation Training Centres - Grant ID: IC230100036
Funder
Australian Research Council
Funding Amount
$4,999,600.00
Summary
ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical ....ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical production, more resilient spacecraft and robust regulatory frameworks. Industries and communities will benefit from a future workforce prepared for safe adoption, development and delivery of emerging techniques and advanced radiation technologies, enhancing Australia’s prosperity and security.Read moreRead less
ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100084
Funder
Australian Research Council
Funding Amount
$269,020.00
Summary
Flexible Flame Aerosol Synthesis Technology. Funding is requested to establish a world-leading fabrication facility for nanostructured materials via flame synthesis. This is a scalable fabrication route used for industrial production of most nanoparticle commodities. The aim is to advance current capabilities by providing control over the reaction environment and flame reaction sources. This will extend the range of feasible materials from the current metal oxides to a broad family of nitrides, ....Flexible Flame Aerosol Synthesis Technology. Funding is requested to establish a world-leading fabrication facility for nanostructured materials via flame synthesis. This is a scalable fabrication route used for industrial production of most nanoparticle commodities. The aim is to advance current capabilities by providing control over the reaction environment and flame reaction sources. This will extend the range of feasible materials from the current metal oxides to a broad family of nitrides, sulphides, and metal-organic frameworks, enabling the engineering of electrocatalysts, optoelectronic- and bio-materials. Benefits are expected in terms of fundamental and applied knowledge generation, with impact to the Australian industry sectors of Advanced Manufacturing, Energy and Health.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100016
Funder
Australian Research Council
Funding Amount
$3,123,492.00
Summary
ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therap ....ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therapeutics. The use of an individual patient’s cellular and molecular research findings will ultimately enable personalised diagnostic and therapeutic decisions.Read moreRead less
Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resou ....Transforming Microgrid to Virtual Power Plant –ICT Frameworks,Tools,Control. The project aims to enhance large scale renewable penetrations to national power grid by advancing control, optimization, and ancillary services of Virtual Power Plants (VPPs), considering different disruptive events including recent South Australian blackout. This project expects to create new control, frame communication architecture, develop plug and play type IoT enabled grid interfacing inverter, and optimize resource management for distributed VPPs. The anticipated benefits from this institutional level collaborations are that VPPs help in enhancing national power grid operations during normal and disruptive conditions when more renewables are connected and also secure benefits of consumers, prosumers, and grid operators.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100125
Funder
Australian Research Council
Funding Amount
$837,000.00
Summary
National Facility for Infrared Technologies. This project aims to establish a national facility for infrared (IR) technologies. The facility will include advanced imaging and spectroscopy facilities as well as unique tools for wafer-scale mapping of IR materials and devices. Combined, the facility will enable new diagnostic capabilities of supersonic combustion processes, aid establishment of wavelength agile integrated photonic chips and provide non-destructive quantitative electro-optical char ....National Facility for Infrared Technologies. This project aims to establish a national facility for infrared (IR) technologies. The facility will include advanced imaging and spectroscopy facilities as well as unique tools for wafer-scale mapping of IR materials and devices. Combined, the facility will enable new diagnostic capabilities of supersonic combustion processes, aid establishment of wavelength agile integrated photonic chips and provide non-destructive quantitative electro-optical characterisation of IR materials and devices. Establishment of these state-of-the-art capabilities across Australia will have clear benefits in fundamental sciences such as astronomy and quantum information as well as key industry branches in defence, aerospace, communications and security.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less